SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: overlap Ensembl ID: ENSG00000153956
Gene: CACNA2D1 Gene type: protein_coding
Strand: - External links:
Genomic region: chr7:81946444-82443777 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_146200011 chr7:81921997-82022289 Sample_02_1462 Ovary A2780_shMBD3.26 11 25 2609 2 2 400 1005 CACNA2D1,LOC101927356
SE_02_146100011 chr7:81922662-82021918 Sample_02_1461 Ovary A2780_shRen 11 27 2588 2 2 395 1005 CACNA2D1,LOC101927356
SE_02_146300011 chr7:81923411-82020318 Sample_02_1463 Ovary A2780_shMBD3.232 11 30 2520 2 2 371 965 CACNA2D1,LOC101927356
SE_02_014600178 chr7:81924422-81961194 Sample_02_0146 Bone marrow LP-1_SGC-CBP30 178 6 1006 0 2 99 310 CACNA2D1,HGF
SE_02_031100230 chr7:81945341-81989367 Sample_02_0311 Neuroblastoma SK-N-AS 230 4 1119 2 0 227 704 CACNA2D1,HGF
SE_02_055400208 chr7:81952459-81972840 Sample_02_0554 Other Aska shSSX 208 5 546 0 0 79 341 CACNA2D1,LOC101927356
SE_02_031600032 chr7:81955971-81990423 Sample_02_0316 Neuroblastoma CHP212 32 2 886 2 0 152 445 CACNA2D1,HGF
SE_02_054900102 chr7:81956270-81965316 Sample_02_0549 Other Aska shCt 102 6 230 0 0 37 167 CACNA2D1,LOC101927356
SE_02_055100105 chr7:81956396-81966890 Sample_02_0551 Other Aska-BAF47KO1 shSSX 105 1 260 0 0 40 195 CACNA2D1,LOC101927356
SE_02_031600123 chr7:82003528-82022958 Sample_02_0316 Neuroblastoma CHP212 123 1 473 0 0 106 230 CACNA2D1,HGF
SE_02_031100402 chr7:82003539-82023786 Sample_02_0311 Neuroblastoma SK-N-AS 402 1 491 0 0 117 237 CACNA2D1,HGF
SE_02_021001062 chr7:82015570-82052365 Sample_02_0210 Lung MRC-5_N_1DPT 1062 5 906 0 1 95 292 CACNA2D1,HGF
SE_02_024400594 chr7:82015596-82051981 Sample_02_0244 Foreskin foreskin_D11 594 5 894 0 1 95 292 CACNA2D1,HGF
SE_02_094900640 chr7:82019413-82050234 Sample_02_0949 Umbilical artery HUAEC_WT 640 18 766 0 1 66 292 CACNA2D1,LOC101927356
SE_02_156900705 chr7:82029022-82050550 Sample_02_1569 Endothelial Endothelial cells 705 8 535 0 0 29 119 CACNA2D1,LOC101927356
SE_02_130901279 chr7:82029873-82040625 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 1279 3 259 0 0 16 70 CACNA2D1,LOC101927356
SE_02_020901273 chr7:82031008-82054973 Sample_02_0209 Lung MRC-5_MRC5_1DPT 1273 8 596 0 0 43 58 CACNA2D1,HGF
SE_02_143800842 chr7:82032969-82054838 Sample_02_1438 Liver LSEC 842 7 554 0 0 39 36 CACNA2D1,LOC101927356
SE_02_143600788 chr7:82033039-82054135 Sample_02_1436 Liver LSEC-Ctrl 788 10 531 0 0 38 33 CACNA2D1,LOC101927356
SE_02_143701120 chr7:82033592-82054387 Sample_02_1437 Liver LSEC-TNF 1120 7 527 0 0 36 23 CACNA2D1,LOC101927356
SE_02_049901564 chr7:82033603-82054187 Sample_02_0499 Fetal lung IMR90 IR Senescence 1564 10 522 0 0 36 23 CACNA2D1,LOC101927356,HGF
SE_02_077600172 chr7:82034169-82055019 Sample_02_0776 Pancreas EndoC-BH1 172 3 539 0 0 31 23 CACNA2D1,LOC101927356
SE_02_041100208 chr7:82039644-82055192 Sample_02_0411 Liver TTC549_untreated 208 2 404 0 0 28 0 CACNA2D1,HGF
SE_02_041200193 chr7:82041725-82055204 Sample_02_0412 Liver TTC549_Doxycycline 193 1 332 0 0 24 0 CACNA2D1,HGF
SE_02_049500997 chr7:82045246-82052255 Sample_02_0495 Islets differentiated hESCs Early LSD1 inhibition PP2 997 4 163 0 0 15 0 CACNA2D1,LOC101927356
SE_02_062000972 chr7:82105739-82110702 Sample_02_0620 Aortic Aortic Endothelial Cells_DF 972 3 163 1 3 13 0 CACNA2D1,LOC101927356
SE_02_069300131 chr7:82148204-82215434 Sample_02_0693 Lung NCI-H69_no infection 131 44 1888 56 11 146 22 CACNA2D1,LOC101927356
SE_02_041200220 chr7:82149777-82175298 Sample_02_0412 Liver TTC549_Doxycycline 220 2 755 19 5 70 22 CACNA2D1
SE_02_068701061 chr7:82149973-82176680 Sample_02_0687 Lung NCI-H146_no infection 1061 13 784 20 6 72 22 CACNA2D1,LOC101927356
SE_02_129000283 chr7:82150286-82179078 Sample_02_1290 Lung NCI-H69_p8-15 283 11 833 22 6 74 22 CACNA2D1,LOC101927356
SE_02_075400825 chr7:82154691-82160207 Sample_02_0754 Embryo ES-derived progenitors Pancreatic Progenitors 1 WT 825 1 166 2 2 12 0 CACNA2D1,LOC101927356
SE_02_006400605 chr7:82164887-82181516 Sample_02_0064 Embryo DN-Early_G1 605 3 485 15 2 52 22 CACNA2D1
SE_02_006500466 chr7:82165335-82182186 Sample_02_0065 Embryo KO2-Late_G1 466 2 480 15 2 51 22 CACNA2D1
SE_02_068700061 chr7:82190925-82297495 Sample_02_0687 Lung NCI-H146_no infection 61 41 2787 95 9 264 36 CACNA2D1
SE_02_000600110 chr7:82192327-82192602 Sample_02_0006 Cervical cervical-cancer_parental 110 1 4 0 0 0 0 CACNA2D1
SE_02_052300195 chr7:82198747-82290929 Sample_02_0523 Lung NCIH810 195 29 2398 75 6 235 36 CACNA2D1
SE_02_129000022 chr7:82229374-82300435 Sample_02_1290 Lung NCI-H69_p8-15 22 23 1835 46 1 201 36 CACNA2D1
SE_02_069300087 chr7:82229420-82293544 Sample_02_0693 Lung NCI-H69_no infection 87 44 1659 37 0 191 36 CACNA2D1
SE_02_123700553 chr7:82230060-82290101 Sample_02_1237 Skin MKL2_virus_positive 553 20 1561 34 0 189 13 CACNA2D1
SE_02_123600190 chr7:82230151-82290264 Sample_02_1236 Skin MKL1_virus_positive 190 28 1560 33 0 189 25 CACNA2D1
SE_02_031200017 chr7:82230563-82446115 Sample_02_0312 Neuroblastoma SK-N-BE_2-C 17 17 5767 193 15 611 302 CACNA2D1
SE_02_142900912 chr7:82231587-82314711 Sample_02_1429 Blood GM12878_WT 912 20 2153 64 1 205 36 CACNA2D1
SE_02_029700641 chr7:82234567-82289454 Sample_02_0297 Neuroblastoma CLB-CAR 641 6 1429 30 0 168 0 CACNA2D1
SE_01_005000206 chr7:82240829-82272285 Sample_01_0050 Embryo neural-cell 206 6 805 17 0 96 0 CACNA2D1
SE_02_033900385 chr7:82252905-82271687 Sample_02_0339 Neuroblastoma NGP 385 5 464 12 0 61 0 CACNA2D1
SE_02_129100176 chr7:82256472-82275494 Sample_02_1291 Lung NCI-H889_p8-15 176 5 486 11 0 67 0 CACNA2D1
SE_02_022000384 chr7:82256838-82271298 Sample_02_0220 Brain BE2C_1 384 4 364 9 0 57 0 CACNA2D1
SE_02_106400385 chr7:82262265-82271386 Sample_02_1064 Brain CLB-GA-Dinaciclib_8h 385 4 239 7 0 38 0 CACNA2D1
SE_02_030600153 chr7:82312436-82390403 Sample_02_0306 Autonomic ganglia SH-SY5Y 153 8 2152 77 10 215 65 CACNA2D1
SE_02_003301133 chr7:82312699-82377873 Sample_02_0033 Pancreas pancreatic-islets-F 1133 8 1743 68 9 171 65 CACNA2D1
SE_02_068900126 chr7:82312950-82393875 Sample_02_0689 Lung NCI-H446_no infection 126 34 2255 75 10 219 65 CACNA2D1
SE_01_009400150 chr7:82313687-82455757 Sample_01_0094 Gastrocnemius medialis gastrocnemius medialis_54y 150 49 3837 142 15 430 266 CACNA2D1
SE_02_150800120 chr7:82313908-82389819 Sample_02_1508 Brain NGPz_untreat 120 26 2101 70 10 212 65 CACNA2D1
SE_02_021100725 chr7:82317129-82361355 Sample_02_0211 Lung MRC-5_NFD_1DPT 725 7 1161 41 5 104 65 CACNA2D1
SE_02_148600382 chr7:82317608-82349992 Sample_02_1486 Bone SK-N-MC 382 8 836 33 3 65 65 CACNA2D1
SE_02_148500035 chr7:82317674-82405496 Sample_02_1485 Bone SK-ES-1 35 24 2487 78 9 196 65 CACNA2D1
SE_02_106100071 chr7:82318299-82398320 Sample_02_1061 Bone TC71_WT 71 22 2256 68 9 191 65 CACNA2D1
SE_02_148800071 chr7:82318299-82398320 Sample_02_1488 Bone TC-71 71 22 2256 68 9 191 65 CACNA2D1
SE_02_147600185 chr7:82318689-82398272 Sample_02_1476 Bone EW-1 185 24 2248 68 9 191 65 CACNA2D1
SE_02_142900069 chr7:82327419-82447947 Sample_02_1429 Blood GM12878_WT 69 35 3324 119 12 370 266 CACNA2D1
SE_01_002100769 chr7:82334936-82377212 Sample_01_0021 Skin bipolar-neuron 769 5 1182 33 5 103 65 CACNA2D1
SE_02_034100449 chr7:82334956-82388600 Sample_02_0341 Autonomic ganglia SH-SY5Y_untreat 449 10 1533 41 6 146 62 CACNA2D1
SE_02_147800123 chr7:82335474-82398791 Sample_02_1478 Bone EW-3 123 10 1835 45 6 153 34 CACNA2D1
SE_02_022000164 chr7:82336185-82377197 Sample_02_0220 Brain BE2C_1 164 7 1145 33 5 89 34 CACNA2D1
SE_02_033900190 chr7:82342953-82385754 Sample_02_0339 Neuroblastoma NGP 190 5 1229 38 5 119 34 CACNA2D1
SE_01_007600568 chr7:82347080-82455875 Sample_01_0076 Gastrocnemius medialis gastrocnemius-medialis 568 19 2989 106 11 343 235 CACNA2D1
SE_02_070200115 chr7:82348279-82398043 Sample_02_0702 Bone David_TC71 115 21 1479 38 6 128 34 CACNA2D1
SE_02_029700130 chr7:82357819-82447111 Sample_02_0297 Neuroblastoma CLB-CAR 130 9 2502 90 9 310 201 CACNA2D1
SE_02_128300210 chr7:82360556-82384337 Sample_02_1283 Lung NCI-H2107_p8-15 210 10 713 24 4 88 0 CACNA2D1
SE_02_148700104 chr7:82367274-82394815 Sample_02_1487 Bone TC-32 104 9 850 20 4 85 0 CACNA2D1
SE_02_068400060 chr7:82367535-82385479 Sample_02_0684 Lung DMS79 60 9 539 19 3 70 0 CACNA2D1
SE_02_147900448 chr7:82367589-82398620 Sample_02_1479 Bone EW-7 448 13 949 24 4 88 0 CACNA2D1
SE_02_128000713 chr7:82368347-82398470 Sample_02_1280 Bone Mesenchymal stem cells_SPC_mutation_ EF1 713 9 927 22 4 88 0 CACNA2D1
SE_02_106000161 chr7:82368604-82398380 Sample_02_1060 Bone TC71_SA2 KO 161 13 922 21 3 87 0 CACNA2D1
SE_02_147500294 chr7:82371216-82398170 Sample_02_1475 Bone CHLA-25 294 5 846 20 3 87 0 CACNA2D1
SE_02_148000886 chr7:82375601-82399170 Sample_02_1480 Bone MHH-ES-1 886 12 729 16 2 69 0 CACNA2D1
SE_01_006400417 chr7:82375796-82398828 Sample_01_0064 Brain: derived from metastatic site: supra-orbital area SK-N-MC 417 9 709 16 2 67 0 CACNA2D1
SE_02_148600360 chr7:82376172-82398288 Sample_02_1486 Bone SK-N-MC 360 10 685 15 1 63 0 CACNA2D1
SE_02_148100498 chr7:82376544-82398759 Sample_02_1481 Bone MIC 498 9 682 14 1 62 0 CACNA2D1
SE_02_070100507 chr7:82384325-82398053 Sample_02_0701 Bone David_TC32 507 10 430 5 1 18 0 CACNA2D1
SE_02_148300767 chr7:82384382-82397948 Sample_02_1483 Bone RD-ES 767 7 426 5 1 18 0 CACNA2D1
SE_02_038200846 chr7:82406608-82420448 Sample_02_0382 Heart purified cardiomyocyte G296S mutants 846 1 345 4 3 35 0 CACNA2D1
SE_02_052300198 chr7:82407801-82453125 Sample_02_0523 Lung NCIH810 198 12 1134 55 5 199 201 CACNA2D1
SE_02_077600047 chr7:82408804-82455276 Sample_02_0776 Pancreas EndoC-BH1 47 14 1150 59 5 196 201 CACNA2D1
SE_02_069300148 chr7:82409053-82451602 Sample_02_0693 Lung NCI-H69_no infection 148 17 1077 54 4 187 201 CACNA2D1
SE_02_033900135 chr7:82412478-82444860 Sample_02_0339 Neuroblastoma NGP 135 6 826 45 3 150 201 CACNA2D1
SE_02_031800268 chr7:82412898-82447807 Sample_02_0318 Neuroblastoma NB69 268 4 890 50 3 168 201 CACNA2D1
SE_02_034100458 chr7:82412946-82450912 Sample_02_0341 Autonomic ganglia SH-SY5Y_untreat 458 8 977 53 3 173 201 CACNA2D1
SE_02_030300218 chr7:82413016-82446397 Sample_02_0303 Neuroblastoma LAN1 218 5 856 48 3 163 201 CACNA2D1
SE_02_029800261 chr7:82413117-82446412 Sample_02_0298 Neuroblastoma CLB-GA 261 5 852 49 3 163 201 CACNA2D1
SE_02_030000351 chr7:82413178-82446651 Sample_02_0300 Neuroblastoma CLB-PE 351 5 854 49 3 163 201 CACNA2D1
SE_02_077500248 chr7:82431867-82453791 Sample_02_0775 Pancreas EndoC-BH1_SE 248 6 502 34 1 139 201 CACNA2D1
SE_02_031300514 chr7:82434454-82445746 Sample_02_0313 Neuroblastoma SK-N-DZ 514 1 246 16 0 117 201 CACNA2D1
SE_02_029900208 chr7:82434953-82451580 Sample_02_0299 Neuroblastoma CLB-MA 208 3 381 23 0 130 201 CACNA2D1
SE_02_106400764 chr7:82435258-82446525 Sample_02_1064 Brain CLB-GA-Dinaciclib_8h 764 5 244 18 0 120 201 CACNA2D1
SE_02_030600479 chr7:82435494-82452191 Sample_02_0306 Autonomic ganglia SH-SY5Y 479 2 390 22 0 130 201 CACNA2D1
SE_02_030800438 chr7:82436416-82445918 Sample_02_0308 Neuroblastoma SJNB1 438 2 196 14 0 112 201 CACNA2D1
SE_02_068400306 chr7:82436967-82446941 Sample_02_0684 Lung DMS79 306 6 214 17 0 103 201 CACNA2D1
SE_02_141700227 chr7:82438439-82444774 Sample_02_1417 Brain SF7761 227 2 137 9 0 79 201 CACNA2D1
SE_02_069400082 chr7:82439934-82451799 Sample_02_0694 Lung NCI-H82_no infection 82 3 280 13 0 102 201 CACNA2D1
SE_02_096200745 chr7:82440318-82445282 Sample_02_0962 Brain H3.3K27M_Tumor-derived cell-line_DIPGXIIIp11_cells 745 2 107 4 0 76 201 CACNA2D1
SE_02_068600507 chr7:82440440-82445371 Sample_02_0686 Lung NCI-H128_no infection 507 3 106 4 0 78 201 CACNA2D1
SE_02_025100430 chr7:82440846-82446684 Sample_02_0251 Autonomic ganglia SH-SY5Y-MYCN-OFF 430 1 124 7 0 88 201 CACNA2D1
SE_02_097400263 chr7:82441359-82444610 Sample_02_0974 Brain H3.3K27M-KO_DIPGXIII-C14-nKO-Rx_PARENTAL_cells 263 1 70 3 0 59 201 CACNA2D1
Genomic distribution of SEs associated with CACNA2D1
Genome Browser

The strength of the tissue affected by the gene

Expression of CACNA2D1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)