SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: lasso Ensembl ID: ENSG00000130513
Gene: GDF15 Gene type: protein_coding
Strand: + External links:
Genomic region: chr19:18374731-18389176 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_059300016 chr19:18278075-18319283 Sample_02_0593 Fetal spleenocytes fetal naive T cells 16 8 1243 112 6 133 1364 LSM4,MIR3188,JUND,PDE4C,PGPEP1,LOC729966,KIAA1683,IL12RB1,GDF15,MAST3,ARRDC2,SSBP4,MPV17L2,LRRC25
SE_00_003100029 chr19:18278352-18343875 Sample_00_0031 Placenta placenta 29 10 1881 159 12 139 1706 MIR3188,PGPEP1,JUND,LSM4,PDE4C,LOC729966,GDF15,KIAA1683,MIR3189,IFI30,ISYNA1,LRRC25,LS4,RAB3A,SSBP4
SE_02_113900790 chr19:18278539-18305704 Sample_02_1139 Retinal Pigmented Epithelial RPE1-anaphase/telophase 790 7 768 84 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_093700303 chr19:18278572-18306016 Sample_02_0937 Retinal Pigmented Epithelial RPE190_Con 303 7 777 84 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_113800903 chr19:18278681-18318444 Sample_02_1138 Retinal Pigmented Epithelial RPE1-prometaphase 903 6 1191 107 5 133 1364 LSM4,MIR3188,JUND,PDE4C,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_158200376 chr19:18278728-18305756 Sample_02_1582 Renal OS-RC-2 376 5 759 83 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,ISYNA1,GDF15
SE_02_059100005 chr19:18278868-18320509 Sample_02_0591 PBMCs adult CD4+CD25-CD45RA+CD27+ naive T cells 5 11 1247 110 5 133 1364 LSM4,MIR3188,JUND,PDE4C,PGPEP1,LOC729966,KIAA1683,ARRDC2,C19orf60,ISYNA1,GDF15,MPV17L2
SE_02_093600642 chr19:18279058-18305853 Sample_02_0936 Retinal Pigmented Epithelial RPE188_TnT 642 6 753 82 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_108500927 chr19:18279085-18305832 Sample_02_1085 Retinal Pigmented Epithelial hTERT-RPE1 927 7 750 82 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_093500077 chr19:18279104-18306125 Sample_02_0935 Retinal Pigmented Epithelial RPE188_Con 77 9 757 83 2 112 722 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_087801263 chr19:18279152-18318959 Sample_02_0878 Ovary SVOG3e cells_noDox_control 1263 5 1185 105 5 133 1364 LSM4,MIR3188,JUND,PDE4C,PGPEP1,LOC729966,KIAA1683,ISYNA1,GDF15,ELL,MPV17L2
SE_02_113701124 chr19:18279199-18305745 Sample_02_1137 Retinal Pigmented Epithelial RPE1-interphase 1124 6 741 81 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_071901025 chr19:18279291-18305420 Sample_02_0719 Pancreas SUIT2_TP63dN_DOX 1025 8 728 80 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,GDF15,MPV17L2
SE_02_093800640 chr19:18279361-18305753 Sample_02_0938 Retinal Pigmented Epithelial RPE190_TnT 640 6 737 81 1 112 707 MIR3188,JUND,PDE4C,LSM4,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,FKBP8,SSBP4
SE_02_066600268 chr19:18279373-18318541 Sample_02_0666 Prostate RWPE1 Lacz rep1 268 5 1170 105 5 133 1364 LSM4,MIR3188,JUND,PDE4C,PGPEP1,LOC729966,KIAA1683,RAB3A,GDF15,PIK3R2,ELL,SSBP4,MPV17L2
SE_02_062200176 chr19:18284048-18321487 Sample_02_0622 Blood EOL1_Naive 176 25 1139 95 4 41 657 LSM4,PDE4C,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,C19orf60,ISYNA1,KXD1,RAB3A,GDF15,PIK3R2,ELL,SSBP4,MPV17L2,LRRC25
SE_01_010500416 chr19:18287834-18334493 Sample_01_0105 Thyroid gland thyroid gland_54y 416 12 1372 97 8 37 786 LSM4,PDE4C,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,ISYNA1,RAB3A,GDF15,PIK3R2,SSBP4,MPV17L2,LRRC25
SE_02_093001083 chr19:18290846-18295013 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 1083 1 129 10 0 7 0 PDE4C,LSM4,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,GDF15,ELL,MPV17L2
SE_02_092901247 chr19:18290893-18294581 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 1247 1 113 9 0 0 0 PDE4C,LSM4,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,GDF15,ELL,MPV17L2
SE_02_062000441 chr19:18291573-18320999 Sample_02_0620 Aortic Aortic Endothelial Cells_DF 441 8 928 59 4 34 657 LSM4,PDE4C,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,GDF15
SE_02_100500295 chr19:18291641-18305231 Sample_02_1005 Brain Lateral temporal lobe_11T_Old 295 4 400 29 0 13 0 PDE4C,LSM4,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,ISYNA1,GDF15,PIK3R2,MAST3,MPV17L2,LRRC25
SE_02_100300128 chr19:18291664-18305094 Sample_02_1003 Brain Lateral temporal lobe_19T_Young 128 4 394 29 0 13 0 PDE4C,LSM4,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,ISYNA1,GDF15,PIK3R2,MAST3,MPV17L2,LRRC25
SE_02_100400168 chr19:18291880-18305177 Sample_02_1004 Brain Lateral temporal lobe_10T_Old 168 5 393 29 0 13 0 PDE4C,LSM4,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,ISYNA1,GDF15,PIK3R2,MAST3,MPV17L2,LRRC25
SE_02_100600185 chr19:18291965-18307427 Sample_02_1006 Brain Lateral temporal lobe_13T_Old 185 7 474 36 2 13 258 LSM4,PDE4C,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,ISYNA1,RAB3A,GDF15,PIK3R2,MAST3,MPV17L2,LRRC25
SE_00_005501262 chr19:18302816-18306249 Sample_00_0055 Spleen spleen 34y 1262 1 112 8 2 0 33 LSM4,JUND,PGPEP1,LOC729966,MIR3188,KIAA1683,PDE4C,IL12RB1,GDF15,MAST3,ARRDC2,MPV17L2,LRRC25
SE_02_093000435 chr19:18315564-18323107 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 435 1 216 19 4 5 142 LSM4,MIR3188,JUND,KIAA1683,PGPEP1,PDE4C,GDF15,SSBP4,MPV17L2
SE_02_092900752 chr19:18316766-18323069 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 752 1 181 17 3 2 62 LSM4,MIR3188,JUND,KIAA1683,PGPEP1,PDE4C,GDF15,SSBP4,MPV17L2
SE_02_087500721 chr19:18361079-18376721 Sample_02_0875 Peripheral blood Peripheral blood-derived mast cells 721 1 486 38 2 5 1247 PGPEP1,MIR3189,LRRC25,LSM4,SSBP4,GDF15,KIAA1683,ISYNA1,JUND,MPV17L2,SLC27A1
SE_02_098900300 chr19:18361687-18390924 Sample_02_0989 Kidney kidney cortex_WT 300 1 833 79 3 26 1693 PGPEP1,MIR3189,GDF15,ISYNA1,LRRC25,LSM4,SSBP4,KIAA1683,JUND
SE_02_088301368 chr19:18362568-18380852 Sample_02_0883 Ovary SVOG3e_cells_Dox_12h_transduced with V5-FOXL2 C134W 1368 6 556 46 3 10 1247 PGPEP1,MIR3189,LRRC25,LSM4,SSBP4,GDF15,KIAA1683,ISYNA1,JUND,ELL
SE_04_000500255 chr19:18363247-18388980 Sample_04_0005 Lung A549 FOXA2 overexpressed 255 7 745 69 3 24 1614 PGPEP1,MIR3189,GDF15,ISYNA1,LRRC25,LSM4,SSBP4,JUND
SE_02_088201237 chr19:18363610-18380920 Sample_02_0882 Ovary SVOG3e_cells_noDox_transduced with V5-FOXL2 C134W 1237 5 520 43 3 7 1170 PGPEP1,MIR3189,LRRC25,LSM4,SSBP4,GDF15,KIAA1683,ISYNA1,JUND,ELL
SE_02_056100244 chr19:18363827-18389104 Sample_02_0561 Lung A549_1 244 10 725 69 3 23 1524 PGPEP1,MIR3189,GDF15,ISYNA1,LRRC25,LSM4,SSBP4,JUND
SE_02_088001534 chr19:18363920-18378865 Sample_02_0880 Ovary SVOG3e cells_noDox_transduced_V5-FOXL2_WT 1534 3 453 33 3 2 1106 PGPEP1,MIR3189,LRRC25,LSM4,SSBP4,GDF15,KIAA1683,ISYNA1,JUND,ELL
SE_01_011200521 chr19:18364204-18380759 Sample_01_0112 Embryonic kidney HEK293_encode 521 5 487 40 3 6 1076 PGPEP1,MIR3189,LRRC25,LSM4,SSBP4,GDF15,C19orf60,ISYNA1,JUND
SE_02_092700441 chr19:18388081-18418500 Sample_02_0927 Peripheral blood neutrophils_US 441 10 810 79 3 50 868 LRRC25,GDF15,MIR3189,ISYNA1,SSBP4,PGPEP1
SE_02_152900947 chr19:18390051-18430498 Sample_02_1529 Peripheral blood neutrophils_0BC75 947 13 1105 95 5 64 1128 SSBP4,LRRC25,GDF15,MIR3189,ISYNA1,PGPEP1
SE_01_003900294 chr19:18401423-18442822 Sample_01_0039 Haematopoietic and lymphoid tissue bone marrow K562 294 5 1144 91 5 192 2690 SSBP4,ELL,ISYNA1,GDF15,MIR3189,LRRC25,JUND,KIAA1683,LS4,PGPEP1
SE_02_046100110 chr19:18401459-18429400 Sample_02_0461 Blood MV-4-11-B cells 110 8 761 59 4 53 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C
SE_04_000100180 chr19:18401979-18443383 Sample_04_0001 Blood heat shocked K562 180 8 1138 91 5 197 2790 ISYNA1,SSBP4,ELL,GDF15,MIR3189,LRRC25,PGPEP1,KIAA1683,LSM4,JUND,PDE4C
SE_02_062200466 chr19:18402097-18430647 Sample_02_0622 Blood EOL1_Naive 466 11 782 63 4 53 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,KXD1,PGPEP1,LSM4,KLHL26
SE_02_098800531 chr19:18402693-18429917 Sample_02_0988 Blood K562_EPZ 531 8 749 59 3 53 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PGPEP1,KIAA1683,LSM4,JUND,PDE4C
SE_02_111600037 chr19:18407730-18440503 Sample_02_1116 Haematopoietic and lymphoid tissue bone marrow K562_native 37 7 943 68 3 192 2657 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PGPEP1,KIAA1683,LSM4,JUND,PDE4C
SE_02_054500243 chr19:18407894-18434469 Sample_02_0545 Bone marrow K562 WT 243 5 769 53 2 139 1624 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PGPEP1,KIAA1683,LSM4,JUND,PDE4C
SE_02_122900735 chr19:18413065-18424620 Sample_02_1229 Haematopoietic and lymphoid tissue bone marrow K562_Control 735 1 298 17 1 40 212 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_04_000200288 chr19:18413509-18422182 Sample_04_0002 Blood cold shocked K562 288 1 208 14 0 40 212 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_109900413 chr19:18413557-18420886 Sample_02_1099 Haematopoietic and lymphoid tissue bone marrow K562_DMSO_noIFNG 413 1 176 14 0 40 212 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_054600080 chr19:18413840-18434180 Sample_02_0546 Bone marrow K562_MYO1D Non-hub KO 80 3 584 40 2 137 1559 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_103300440 chr19:18413845-18421190 Sample_02_1033 Haematopoietic and lymphoid tissue bone marrow K562 440 1 174 13 0 40 212 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_113000242 chr19:18413917-18421967 Sample_02_1130 Haematopoietic and lymphoid tissue bone marrow K562_??Np63?? expressing 242 1 190 13 0 40 212 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_094100282 chr19:18414089-18434268 Sample_02_0941 Brain T98G 282 3 578 40 2 138 1582 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,JUND
SE_02_095000678 chr19:18414498-18434563 Sample_02_0950 Umbilical vein HUVEC_WT 678 6 576 40 3 139 1654 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PDE4C,KXD1,PGPEP1,JUND,LSM4
SE_02_146900199 chr19:18414515-18434366 Sample_02_1469 Umbilical Vein HUVEC 199 4 570 38 2 139 1609 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,KXD1,PGPEP1,JUND,LSM4
SE_02_148600466 chr19:18414590-18434288 Sample_02_1486 Bone SK-N-MC 466 5 567 38 2 138 1589 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,TMEM59L
SE_02_054700121 chr19:18414637-18433990 Sample_02_0547 Bone marrow K562_MYO1D_Hub_KO 121 3 551 38 2 137 1480 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_083100835 chr19:18414641-18433980 Sample_02_0831 Umblical vein HUVECs_TNF0min 835 6 551 38 2 137 1477 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,KXD1,PGPEP1,JUND,LSM4
SE_02_142400180 chr19:18414654-18433708 Sample_02_1424 Haematopoietic and lymphoid tissue bone marrow K562_Triptolide_4h 180 4 551 38 2 96 1386 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,LSM4
SE_02_151800256 chr19:18414678-18430117 Sample_02_1518 Umbilical vein HUVEC_Scr 256 3 421 27 2 53 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,KXD1,PGPEP1,JUND,LSM4
SE_02_152000731 chr19:18414707-18417696 Sample_02_1520 Umbilical vein HUVEC_Notch1kd_IL1beta 731 4 70 6 0 16 0 GDF15,MIR3189,ISYNA1,LRRC25,SSBP4,PDE4C,KXD1,PGPEP1,JUND,LSM4
SE_02_062800015 chr19:18414717-18435785 Sample_02_0628 Brain CHP-134 15 8 613 44 3 149 1945 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PDE4C,KXD1,JUND,FKBP8,LSM4
SE_02_062000602 chr19:18415161-18429585 Sample_02_0620 Aortic Aortic Endothelial Cells_DF 602 3 395 23 2 47 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,C19orf60,KXD1,PGPEP1,JUND,LSM4
SE_01_011700504 chr19:18415167-18430059 Sample_01_0117 Lung fibroblast of lung 504 4 410 25 2 46 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PGPEP1,JUND,ELL,FKBP8,LSM4,KLHL26
SE_02_069400124 chr19:18415914-18430047 Sample_02_0694 Lung NCI-H82_no infection 124 3 390 25 2 45 502 SSBP4,GDF15,MIR3189,ISYNA1,LRRC25,PDE4C,PGPEP1,UBA52,LSM4
SE_02_116300138 chr19:18416530-18434391 Sample_02_1163 Embryonic kidney HEK293 no dox 138 5 522 34 2 131 1615 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PDE4C,KXD1,PGPEP1,CRLF1,JUND,TMEM59L,LSM4
SE_02_111400198 chr19:18416535-18435204 Sample_02_1114 Embryonic kidney HEK293 198 3 554 38 3 138 1812 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PDE4C,KXD1,PGPEP1,CRLF1,JUND,TMEM59L,LSM4
SE_01_011200404 chr19:18416565-18434737 Sample_01_0112 Embryonic kidney HEK293_encode 404 5 534 37 3 131 1700 ISYNA1,SSBP4,GDF15,MIR3189,LRRC25,PDE4C,KXD1,PGPEP1,CRLF1,JUND,TMEM59L,LSM4
SE_02_092900064 chr19:18475362-18530764 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 64 28 1595 164 15 39 226 ELL,KXD1,ISYNA1,UBA52,FKBP8,C19orf60,PGPEP1,GDF15,JUND,COPE,TMEM59L,LSM4,KLHL26,SSBP4,CRLF1,CRTC1
SE_00_003100252 chr19:18476809-18523069 Sample_00_0031 Placenta placenta 252 6 1347 138 13 38 135 ELL,UBA52,ISYNA1,C19ORF50,FKBP8,C19orf60,CRLF1,CRTC1,GDF15,KXD1,SSBP4,TE59L
SE_02_093000207 chr19:18476877-18551780 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 207 34 2187 203 13 113 1466 FKBP8,ELL,KXD1,ISYNA1,C19ORF60,UBA52,C19orf60,PGPEP1,GDF15,JUND,COPE,TMEM59L,LSM4,KLHL26,SSBP4,CRLF1,CRTC1
Genomic distribution of SEs associated with GDF15
Genome Browser

The strength of the tissue affected by the gene

Expression of GDF15

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)