SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000091831
Gene: ESR1 Gene type: protein_coding
Strand: + External links:
Genomic region: chr6:151656691-152129619 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_108800024 chr6:151602523-151717085 Sample_02_1088 Mammary gland T47D_shCtrl_45min 24 40 3200 150 78 184 589 CCDC170,ESR1
SE_02_108700040 chr6:151602694-151717234 Sample_02_1087 Mammary gland T47D_shCtrl_shRING1B_0 40 40 3195 149 78 184 589 CCDC170,ESR1
SE_02_039400017 chr6:151603298-151707269 Sample_02_0394 Mammary gland T-47D_2 17 25 2900 144 76 182 589 C6ORF97,ESR1
SE_02_108600050 chr6:151603533-151717110 Sample_02_1086 Mammary gland T47D_shCtrl_0hr 50 36 3165 143 77 183 589 CCDC170,ESR1
SE_02_108900039 chr6:151603668-151703557 Sample_02_1089 Mammary gland T47D_shCtrl_shRING1B_45min 39 24 2779 141 73 171 589 CCDC170,ESR1
SE_02_109300019 chr6:151603723-151717099 Sample_02_1093 Mammary gland T47D_shCtrl_shRING1B_24hr 19 32 3160 142 77 183 589 CCDC170,ESR1
SE_02_000200001 chr6:151605043-151724557 Sample_02_0002 Mammary gland MCF-7_10Gygamma_2.5h 1 4 3324 134 79 193 589 C6ORF97,ESR1
SE_02_062500010 chr6:151605110-151707119 Sample_02_0625 Mammary gland WS8_4OHT 10 17 2838 133 76 181 589 CCDC170,ESR1
SE_02_062700008 chr6:151605397-151716507 Sample_02_0627 Mammary gland WS8_VEH 8 21 3089 134 77 182 589 CCDC170,ESR1
SE_02_011500028 chr6:151605959-151638190 Sample_02_0115 Mammary gland MCF-7 28 2 907 65 34 40 370 C6ORF97,ESR1,CCDC170
SE_02_062600010 chr6:151606007-151716741 Sample_02_0626 Mammary gland WS8_E2 10 17 3074 133 77 182 589 CCDC170,ESR1
SE_02_157500009 chr6:151606900-151717010 Sample_02_1575 Mammary gland MCF7_Mock 9 34 3066 133 76 182 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_080900018 chr6:151606935-151717084 Sample_02_0809 Mammary gland T47D Serum 18 21 3066 133 76 182 589 CCDC170,ESR1
SE_02_109000022 chr6:151607523-151703779 Sample_02_1090 Mammary gland T47D_shCtrl_8hr 22 31 2677 129 72 171 589 CCDC170,ESR1
SE_02_009600003 chr6:151608200-151730857 Sample_02_0096 Mammary gland ZR-75-1_1 3 10 3415 131 80 199 589 C6ORF97,ESR1
SE_01_011300005 chr6:151608359-151724845 Sample_01_0113 Mammary gland MCF-7 5 42 3246 130 78 193 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_081000101 chr6:151608606-151682041 Sample_02_0810 Mammary gland T47D noSerum 101 42 2083 119 53 104 505 CCDC170,ESR1
SE_02_115100046 chr6:151608617-151730306 Sample_02_1151 Mammary gland MCF-7_UNTR 46 63 3385 129 79 198 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_052700009 chr6:151608902-151722480 Sample_02_0527 Mammary gland MCF7_WT 9 39 3145 127 77 193 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_109100021 chr6:151609564-151703454 Sample_02_1091 Mammary gland T47D_shCtrl_shRING1B_8hr 21 32 2610 126 71 167 589 CCDC170,ESR1
SE_02_157800037 chr6:151612415-151716614 Sample_02_1578 Mammary gland MCF7_DAC+455 37 42 2905 125 73 170 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_123400021 chr6:151612472-151717150 Sample_02_1234 Mammary gland T47D_Full 21 37 2922 125 73 170 589 CCDC170,ESR1
SE_02_157600206 chr6:151612544-151636747 Sample_02_1576 Mammary gland MCF7_CPI-455 206 11 705 52 29 28 370 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_040300018 chr6:151612674-151717289 Sample_02_0403 Mammary gland T-47D_untreat 18 14 2920 125 73 170 589 C6ORF97,ESR1
SE_02_056800013 chr6:151613228-151717198 Sample_02_0568 Mammary gland MCF7L_E2_4h 13 40 2904 125 73 170 589 CCDC170,ESR1
SE_02_109200026 chr6:151613407-151717035 Sample_02_1092 Mammary gland T47D_shCtrl_24hr 26 32 2897 125 73 170 589 CCDC170,ESR1
SE_02_053200016 chr6:151613486-151716397 Sample_02_0532 Mammary gland T47D 16 38 2873 124 73 170 589 CCDC170,ESR1
SE_02_146400080 chr6:151613989-151682098 Sample_02_1464 Ovary CAOV4 80 20 1951 114 50 92 505 CCDC170,ESR1
SE_02_052600007 chr6:151614223-151717118 Sample_02_0526 Mammary gland MCF7 TRPS1 KO 7 35 2880 124 73 170 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_056400033 chr6:151614404-151716738 Sample_02_0564 Mammary gland MCF7L-P_E2_1h 33 45 2860 124 73 170 589 CCDC170,ESR1
SE_02_024600006 chr6:151614526-151717441 Sample_02_0246 Mammary gland MCF-7_estradiol 6 6 2878 124 73 170 589 C6ORF97,ESR1
SE_02_157700026 chr6:151614599-151717119 Sample_02_1577 Mammary gland MCF7_DAC 26 44 2871 124 73 170 589 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_032600361 chr6:151615075-151683764 Sample_02_0326 Liver hepatocytes_d3 361 11 1961 113 50 93 505 C6ORF97,ESR1
SE_02_032500487 chr6:151615144-151683709 Sample_02_0325 Liver hepatocytes_d1 487 10 1955 112 50 93 505 C6ORF97,ESR1
SE_02_032700333 chr6:151615458-151683773 Sample_02_0327 Liver hepatocytes_d6 333 10 1952 112 50 92 495 C6ORF97,ESR1
SE_02_067700450 chr6:151615478-151630220 Sample_02_0677 Embryo H1 hESC-derived neural progenitor cells_Smad_6hr 450 8 443 34 22 20 359 CCDC170,ESR1
SE_02_067100057 chr6:151615934-151722333 Sample_02_0671 Mammary gland breast cancer_DSG 57 41 2968 121 74 179 550 CCDC170,ESR1
SE_02_085200107 chr6:151616343-151717102 Sample_02_0852 Mammary gland MCF7L-P 107 24 2821 121 72 166 531 CCDC170,ESR1
SE_02_115900106 chr6:151616343-151717102 Sample_02_1159 Mammary gland MCF7 106 25 2821 121 72 166 531 CCDC170,ESR1,C6orf211,AKAP12,RMND1,ZBTB2
SE_02_125300106 chr6:151626355-151717281 Sample_02_1253 Mammary gland CAMA1 ER+/FGFR1-amplified 106 30 2527 98 56 155 219 ESR1
SE_02_085000024 chr6:151626597-151716901 Sample_02_0850 Mammary gland MCF7L-P_FOXA1-Dox 24 29 2504 97 56 155 219 ESR1
SE_02_077700009 chr6:151627006-151719041 Sample_02_0777 Mammary gland MCF7_TAMR 9 24 2550 96 56 158 219 ESR1,ZBTB2,AKAP12
SE_02_115800021 chr6:151627152-151716689 Sample_02_1158 Mammary gland MCF7_siYTHDC1_E2 21 16 2479 95 55 150 219 ESR1,ZBTB2,AKAP12
SE_02_056500034 chr6:151629761-151716528 Sample_02_0565 Mammary gland MCF7L-P_E2_16h 34 38 2398 89 51 149 219 ESR1
SE_02_007900038 chr6:151632980-151703881 Sample_02_0079 Mammary gland T-47D_1 38 29 1963 82 45 131 219 ESR1
SE_02_146500309 chr6:151647086-151677667 Sample_02_1465 Ovary CAOV4cis 309 6 860 49 18 51 135 ESR1
SE_02_085300026 chr6:151648352-151717284 Sample_02_0853 Mammary gland MCF7L-TamR 26 19 1899 62 42 142 219 ESR1
SE_02_056600086 chr6:151649819-151716792 Sample_02_0566 Mammary gland MCF7L-P_E2_24h 86 34 1842 60 42 142 219 ESR1
SE_02_157600022 chr6:151650599-151716580 Sample_02_1576 Mammary gland MCF7_CPI-455 22 27 1817 59 41 142 219 ESR1,ZBTB2,AKAP12
SE_02_011500009 chr6:151650696-151707512 Sample_02_0115 Mammary gland MCF-7 9 6 1573 58 40 141 219 ESR1,CCDC170
SE_02_056300089 chr6:151650934-151717200 Sample_02_0563 Mammary gland MCF7L-P_0h 89 35 1830 59 41 142 219 ESR1
SE_01_004600196 chr6:151651289-151716917 Sample_01_0046 Mammary gland MCF-7 196 7 1815 59 41 142 219 ESR1
SE_02_062300286 chr6:151651417-151688496 Sample_02_0623 Mammary gland TAMR_E2 286 14 1075 54 22 71 135 ESR1
SE_02_066700042 chr6:151651676-151716566 Sample_02_0667 Mammary gland MCF7_FA 42 24 1789 59 41 142 219 ESR1,ZBTB2,AKAP12
SE_02_005200131 chr6:151652033-151682142 Sample_02_0052 Mammary gland MCF-7_E2 131 8 866 49 18 64 135 ESR1
SE_02_062400283 chr6:151652048-151688169 Sample_02_0624 Mammary gland TAMR_VEH 283 10 1043 54 22 71 135 ESR1
SE_02_107700100 chr6:151652126-151704623 Sample_02_1077 Mammary gland MCF7_TET2KO-E2 100 10 1450 58 38 132 219 ESR1,ZBTB2,AKAP12
SE_02_107600265 chr6:151656570-151688592 Sample_02_1076 Mammary gland MCF7_TET2WT-E2 265 6 934 52 19 71 133 ESR1,ZBTB2,AKAP12
SE_02_056700153 chr6:151657388-151688540 Sample_02_0567 Mammary gland MCF7L-P_TAMR 153 16 911 51 18 71 103 ESR1
SE_02_049600206 chr6:151658857-151704689 Sample_02_0496 Mammary gland C49R 206 8 1278 51 32 131 187 ESR1
SE_02_067200113 chr6:151659458-151717085 Sample_02_0672 Endometrium endometrium cancer_DSG 113 16 1601 52 35 141 187 ESR1
SE_02_067000089 chr6:151659609-151703969 Sample_02_0670 Mammary gland breast cancer FA 89 9 1228 49 31 130 187 ESR1
SE_02_025700366 chr6:151661492-151704725 Sample_02_0257 Endometrioid endometrioid_adenocarcinoma_TumorA 366 6 1209 44 30 129 187 ESR1
SE_02_067400146 chr6:151662289-151693357 Sample_02_0674 Endometrium E1_FA 146 9 890 43 21 92 97 ESR1
SE_02_076600780 chr6:151663646-151682486 Sample_02_0766 Ovary PEO1 780 9 567 34 7 47 51 ESR1
SE_02_061400609 chr6:151665130-151703772 Sample_02_0614 Liposarcoma MLPS_T2 609 13 1087 40 26 106 135 ESR1
SE_02_073900297 chr6:151675325-151701239 Sample_02_0739 Blood Nalm6 297 7 702 22 18 89 46 ESR1,C6orf211
SE_02_115600417 chr6:151675976-151704021 Sample_02_1156 Peripheral blood Day6 Plasmablast CD23- memory B cell 417 7 758 22 21 90 84 ESR1
SE_01_009100726 chr6:151679009-151733228 Sample_01_0091 Uterus uterus 726 9 1470 13 30 119 84 ESR1
SE_02_036200652 chr6:151679234-151692934 Sample_02_0362 Haematopoietic and lymphoid tissue REH 652 2 385 11 14 38 46 ESR1
SE_02_078400866 chr6:151681415-151705481 Sample_02_0784 Blood OSU-CLL 866 7 627 9 20 80 84 ESR1
SE_01_004000091 chr6:151689239-151765644 Sample_01_0040 Haematopoietic and lymphoid tissue Karpas-422 91 6 1987 8 63 144 123 ESR1
SE_02_011700075 chr6:151689650-151765341 Sample_02_0117 Haematopoietic and lymphoid tissue KARPAS-422 75 13 1966 6 61 140 123 ESR1
SE_02_106500212 chr6:151690473-151764558 Sample_02_1065 Lymphoma KARPAS-422_DMSO_8d 212 21 1931 6 61 133 104 ESR1
SE_02_122401005 chr6:151696868-151730236 Sample_02_1224 Bone marrow normal plasma cell 1005 9 913 1 10 58 38 ESR1
SE_01_009200722 chr6:151796610-151827293 Sample_01_0092 Vagina vagina 722 9 783 24 17 139 399 ESR1
SE_02_000200051 chr6:151802463-151845009 Sample_02_0002 Mammary gland MCF-7_10Gygamma_2.5h 51 6 1128 44 26 154 461 ESR1
SE_01_009100313 chr6:151802922-151823126 Sample_01_0091 Uterus uterus 313 3 513 15 13 111 399 ESR1
SE_02_067200118 chr6:151803247-151831507 Sample_02_0672 Endometrium endometrium cancer_DSG 118 11 737 28 18 124 399 ESR1
SE_02_067400089 chr6:151803451-151822596 Sample_02_0674 Endometrium E1_FA 89 5 494 15 13 109 399 ESR1
SE_02_076600322 chr6:151806577-151830352 Sample_02_0766 Ovary PEO1 322 4 618 23 17 105 330 ESR1
SE_02_067100342 chr6:151806582-151817456 Sample_02_0671 Mammary gland breast cancer_DSG 342 3 271 5 8 83 330 ESR1
SE_02_108600805 chr6:151806795-151815870 Sample_02_1086 Mammary gland T47D_shCtrl_0hr 805 3 227 4 7 72 330 ESR1
SE_02_109000424 chr6:151806900-151816073 Sample_02_1090 Mammary gland T47D_shCtrl_8hr 424 3 230 4 7 72 330 ESR1
SE_02_067000162 chr6:151807250-151815475 Sample_02_0670 Mammary gland breast cancer FA 162 5 207 4 7 63 300 ESR1
SE_02_109100490 chr6:151807369-151815533 Sample_02_1091 Mammary gland T47D_shCtrl_shRING1B_8hr 490 2 209 4 7 63 284 ESR1
SE_02_076600166 chr6:151876464-151919601 Sample_02_0766 Ovary PEO1 166 26 1100 2 5 101 75 ESR1
SE_02_074900634 chr6:151885518-151903712 Sample_02_0749 Mammary gland HCC1599_GSI 634 5 454 0 1 5 0 ESR1
SE_02_074800649 chr6:151885584-151903545 Sample_02_0748 Mammary gland HCC1599_WO 649 4 449 0 1 5 0 ESR1
SE_01_005900489 chr6:151899420-151917665 Sample_01_0059 Lung PC-9 489 3 464 1 2 62 0 ESR1
SE_02_135800771 chr6:151899628-151918477 Sample_02_1358 Other IC8-deltaEGF-L1596H_GSI_2h 771 5 478 1 2 65 0 ESR1
SE_02_135900748 chr6:151899699-151918589 Sample_02_1359 Other IC8-deltaEGF-L1596H_GSI_4h 748 4 475 1 2 65 0 ESR1
SE_02_123100327 chr6:151899723-151916850 Sample_02_1231 Lung PC9_siMED13L-1 327 5 425 1 2 46 0 ESR1
SE_02_048001221 chr6:151899725-151918637 Sample_02_0480 Gingival epithelial HGEP 1221 7 475 1 2 65 0 ESR1
SE_02_123000759 chr6:151899788-151917408 Sample_02_1230 Lung PC9 759 5 437 1 2 59 0 ESR1
SE_02_123200309 chr6:151899796-151916665 Sample_02_1232 Lung PC9_siMED13L-2 309 5 419 1 2 46 0 ESR1
SE_02_123300501 chr6:151899846-151914584 Sample_02_1233 Lung PC9_miR-4497 mimic 501 3 367 1 1 41 0 ESR1
SE_02_103700650 chr6:151899925-151918366 Sample_02_1037 Pharynx FaDu Control 650 4 461 1 2 65 0 ESR1
SE_02_135700672 chr6:151899925-151918378 Sample_02_1357 Other IC8-deltaEGF-L1596H_GSI_0h 672 5 461 1 2 65 0 ESR1
SE_02_071300813 chr6:151899941-151918396 Sample_02_0713 Pancreas BxPC3_sgTP63 813 3 462 1 2 65 0 ESR1
SE_02_060400428 chr6:151899958-151919085 Sample_02_0604 Mammary gland MCF10A_scrshRNA_DMSO 428 6 479 1 2 65 0 ESR1
SE_02_071200702 chr6:151899988-151918762 Sample_02_0712 Pancreas BxPC3_sgNEG 702 3 468 1 2 65 0 ESR1
SE_02_112100631 chr6:151900097-151918393 Sample_02_1121 Neonatal foreskin keratinocytes_Mi2KD 631 9 453 1 2 65 0 ESR1
SE_02_070700906 chr6:151900111-151917576 Sample_02_0707 Pancreas BxPC3 WT 906 6 429 1 2 62 0 ESR1
SE_02_060000516 chr6:151900425-151919380 Sample_02_0600 Mammary gland MCF10A_p53shRNA_DMSO 516 5 476 1 2 65 0 ESR1
SE_02_076601230 chr6:151948418-151969535 Sample_02_0766 Ovary PEO1 1230 7 642 15 2 9 0 ESR1
Genomic distribution of SEs associated with ESR1
Genome Browser

The strength of the tissue affected by the gene

Expression of ESR1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)