SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: proximal Ensembl ID: ENSG00000130775
Gene: THEMIS2 Gene type: protein_coding
Strand: + External links:
Genomic region: chr1:27872543-27886685 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_075300524 chr1:27815907-27831950 Sample_02_0753 Embryo ES-derived progenitors_FG type 524 2 394 20 0 62 474 STX12,PPP1R8,SCARNA1,THEMIS2
SE_02_075700423 chr1:27815945-27832261 Sample_02_0757 Embryo ES-derived progenitors_FOXA2 -/- 423 4 399 20 0 62 474 STX12,PPP1R8,SCARNA1,THEMIS2
SE_02_081700063 chr1:27851255-27893488 Sample_02_0817 Ovary Epithelial ovarian cancer 63 13 1104 114 2 57 1160 RPA2,THEMIS2,PPP1R8,SCARNA1,SMPDL3B
SE_02_103602061 chr1:27852288-27854663 Sample_02_1036 Mammary gland HCC70_XY018 2061 1 14 1 0 0 0 PPP1R8,SCARNA1,THEMIS2
SE_02_081600132 chr1:27852381-27905129 Sample_02_0816 Ovary Clear cell ovarian cancer 132 17 1422 164 5 61 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_048900249 chr1:27852418-27891979 Sample_02_0489 Bone marrow HSCe_23y_F_CD34+,CD38-,Lineage- 249 8 1051 109 2 53 1051 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_133200121 chr1:27852825-27915296 Sample_02_1332 Blood Monomac6_CTRL 121 13 1703 195 7 86 1483 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_048400228 chr1:27853512-27892394 Sample_02_0484 Bone marrow HSCe_23y_CD34+,CD38-,Lineage- 228 10 1051 108 2 54 1091 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_084100394 chr1:27854029-27892745 Sample_02_0841 Blood THP-1_untr 394 10 1059 109 2 54 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_119600569 chr1:27854376-27893078 Sample_02_1196 Brain GBM32 569 20 1063 110 2 54 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_153000034 chr1:27857851-27918506 Sample_02_1530 Peripheral blood neutrophils_0BA0X 34 15 1697 206 7 86 1483 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B,FAM76A,EYA3,STX12
SE_02_092700058 chr1:27858103-27917431 Sample_02_0927 Peripheral blood neutrophils_US 58 14 1659 200 7 85 1483 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B,FAM76A,EYA3,STX12
SE_02_119700378 chr1:27858108-27895357 Sample_02_1197 Brain GBM33 378 19 1034 113 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_061200101 chr1:27858142-27894541 Sample_02_0612 Liposarcoma DDLPS_T2 101 12 1017 107 2 55 1171 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_092800098 chr1:27858149-27917426 Sample_02_0928 Peripheral blood neutrophils_Ecoli 98 13 1657 200 7 85 1483 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B,FAM76A,EYA3,STX12
SE_02_155301161 chr1:27858157-27890326 Sample_02_1553 Gastrointestinal Stromal GIST-2_KIT e11 1161 10 906 92 2 52 1000 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_120000550 chr1:27858187-27893020 Sample_02_1200 Brain GBM36 550 14 974 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_119100139 chr1:27858225-27893317 Sample_02_1191 Brain GBM25 139 12 984 103 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_119500195 chr1:27858228-27895486 Sample_02_1195 Brain GBM29 195 16 1035 114 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_078300238 chr1:27858233-27893000 Sample_02_0783 Blood MEC2 238 7 972 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_157300036 chr1:27858255-27905425 Sample_02_1573 Endothelial Undifferentiated Pleomorphic Sarcoma 36 14 1326 155 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_00_005600481 chr1:27858257-27893109 Sample_00_0056 Sigmoid colon sigmoid colon 3y 481 27 976 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_131300148 chr1:27858257-27893797 Sample_02_1313 Brain hMGLs_CD33_SNP 148 12 997 104 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_115600074 chr1:27858262-27893189 Sample_02_1156 Peripheral blood Day6 Plasmablast CD23- memory B cell 74 18 978 103 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_119200464 chr1:27858263-27892935 Sample_02_1192 Brain GBM26 464 14 971 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_152900043 chr1:27858265-27896000 Sample_02_1529 Peripheral blood neutrophils_0BC75 43 1 1051 114 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B,FAM76A,EYA3,XKR8,STX12
SE_02_061700555 chr1:27858268-27892705 Sample_02_0617 HSPC FL CD34+CD38-/lowCD90+ HSPC 555 8 967 101 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_078200138 chr1:27858272-27895095 Sample_02_0782 Blood MEC1 138 9 1024 112 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_118700462 chr1:27858275-27893570 Sample_02_1187 Brain GBM16 462 14 993 104 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_134000360 chr1:27858276-27913150 Sample_02_1340 Blood acute myeloid leukemia 360 25 1532 182 7 74 1298 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_118600646 chr1:27858277-27893139 Sample_02_1186 Brain GBM15 646 15 975 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_131800118 chr1:27858280-27892871 Sample_02_1318 Brain hMGLs_SORL1-A528T 118 7 967 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_118500383 chr1:27858281-27894541 Sample_02_1185 Brain GBM14 383 14 1013 107 2 55 1171 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_153100029 chr1:27858283-27913061 Sample_02_1531 Peripheral blood neutrophils_0B9ZK 29 12 1530 182 7 74 1298 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B,FAM76A,EYA3,STX12
SE_02_120400834 chr1:27858290-27893012 Sample_02_1204 Brain NB2 834 12 971 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_046500712 chr1:27858293-27875321 Sample_02_0465 Adipose subcutaneous adipocytes 712 6 450 31 0 16 145 THEMIS2,PPP1R8,SCARNA1,RPA2,FGR,EYA3,XKR8,STX12
SE_02_106900394 chr1:27858296-27892438 Sample_02_1069 Bone marrow Bone marrow aspirate 394 10 958 101 2 53 1094 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_138700248 chr1:27858296-27914685 Sample_02_1387 Peripheral blood Mac-1_ALK- 248 15 1588 187 7 77 1450 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_109500264 chr1:27858301-27877717 Sample_02_1095 Blood CD34 Erythroid cells_Don002 264 4 557 48 0 24 261 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_045400361 chr1:27858302-27905408 Sample_02_0454 Th17 lymphocytes Th17-IL-10+ Day 0 361 13 1324 155 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_00_005500101 chr1:27858304-27904986 Sample_00_0055 Spleen spleen 34y 101 14 1318 155 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B,FGR,STX12
SE_02_115700092 chr1:27858307-27892729 Sample_02_1157 Peripheral blood Day6 Plasmablast CD23- memory B cell_G9A-Inhibited 92 18 964 101 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_096600596 chr1:27858319-27892830 Sample_02_0966 Brain H3.3K27M_JN29-BS3 596 12 965 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_075100639 chr1:27858331-27894473 Sample_02_0751 Lymphoma Rec-1_WO 639 14 1011 107 2 55 1167 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_093000579 chr1:27858332-27906578 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 579 26 1351 158 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_139400339 chr1:27858333-27877154 Sample_02_1394 Lymph node anaplastic large cell lymphoma cells_ALK+#208 339 6 520 39 0 24 261 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_155600325 chr1:27858333-27893143 Sample_02_1556 Gastrointestinal Stromal GIST-5_KIT e9 325 15 972 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_057500737 chr1:27858338-27904489 Sample_02_0575 Blood MOLM13_sgLKB1e2 737 10 1301 152 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_131500133 chr1:27858343-27894110 Sample_02_1315 Brain hMGLs_INPP5D SNP 133 12 1005 107 2 53 1130 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_061100445 chr1:27858348-27909707 Sample_02_0611 Liposarcoma DDLPS_T1 445 23 1440 170 6 74 1298 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_135000059 chr1:27858351-27912943 Sample_02_1350 Leukophereses leukophereses_p456 59 20 1526 182 7 74 1298 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_131400080 chr1:27858354-27894740 Sample_02_1314 Brain hMGLs_TREM2-KO 80 15 1014 109 2 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_121800825 chr1:27858358-27892760 Sample_02_1218 Bone marrow Daudi 825 14 964 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_131700105 chr1:27858362-27893019 Sample_02_1317 Brain hMGLs_SORL1-KO 105 14 969 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_01_010400413 chr1:27858375-27905020 Sample_01_0104 Lung upper lobe of left lung 413 10 1317 155 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B,FGR,EYA3,XKR8
SE_02_109600271 chr1:27858383-27876677 Sample_02_1096 Blood CD34 Erythroid cells_Don003 271 3 503 36 0 23 197 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_117500137 chr1:27858386-27895157 Sample_02_1175 Brain GBM03 137 12 1021 112 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_117400264 chr1:27858391-27904979 Sample_02_1174 Brain GBM02 264 19 1316 155 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_136300399 chr1:27858392-27875959 Sample_02_1363 Blood Hudep2 399 6 473 34 0 18 145 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_061300810 chr1:27858392-27885621 Sample_02_0613 Liposarcoma MLPS_T1 810 11 778 63 1 52 826 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_112900594 chr1:27858395-27892754 Sample_02_1129 Adipose visceral adipose_CTL_HCTR13 594 16 963 101 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B,FGR,EYA3,XKR8,STX12
SE_02_145800270 chr1:27858403-27892354 Sample_02_1458 Pancreas THP1+PANC1_shNC 270 12 954 99 2 53 1088 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_057600953 chr1:27858404-27887994 Sample_02_0576 Blood HEL_sgLKB1e2 953 6 841 79 2 52 1000 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_133000502 chr1:27858417-27893162 Sample_02_1330 Blood AMU-AML1 502 18 973 102 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_117300959 chr1:27858496-27892791 Sample_02_1173 Brain GBM01 959 13 961 101 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_057800740 chr1:27858565-27892198 Sample_02_0578 Blood MOLM-13_sgSIK3e4 740 11 948 99 2 53 1074 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_082600488 chr1:27858578-27893565 Sample_02_0826 Stomach gastric tumor 488 31 985 103 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_146000052 chr1:27858615-27916870 Sample_02_1460 Blood Mutz-3 52 18 1636 197 7 85 1483 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_068200374 chr1:27858624-27888903 Sample_02_0682 Blood Kasumi-1 374 7 856 81 2 52 1000 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_075000769 chr1:27858697-27893947 Sample_02_0750 Lymphoma Rec-1_GSI 769 14 993 104 2 53 1114 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_044700646 chr1:27858951-27892663 Sample_02_0447 Lung lung metastasis from primary osteosarcoma tumor M2 646 18 949 99 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_104800703 chr1:27859147-27895449 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 703 14 1008 111 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_134500081 chr1:27859482-27913089 Sample_02_1345 Leukophereses leukophereses_p358 81 22 1500 179 7 74 1298 RPA2,THEMIS2,SCARNA1,PPP1R8,XKR8,SMPDL3B
SE_02_082700594 chr1:27861698-27879439 Sample_02_0827 Stomach normal gastric 594 5 504 39 0 24 261 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_134800050 chr1:27862075-27893093 Sample_02_1348 Leukophereses leukophereses_p408 50 10 877 90 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_078400333 chr1:27862209-27895162 Sample_02_0784 Blood OSU-CLL 333 13 925 100 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_134700137 chr1:27862226-27904967 Sample_02_1347 Leukophereses leukophereses_p401 137 7 1218 143 5 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_046000629 chr1:27862262-27888327 Sample_02_0460 Blood ME-1_I-10-49_6h 629 5 750 68 2 52 1000 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_092900621 chr1:27862390-27892034 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 621 18 845 88 2 52 1056 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_121100829 chr1:27862453-27892671 Sample_02_1211 Brain GBM21 829 14 857 88 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_137501069 chr1:27862489-27876485 Sample_02_1375 Pancreas Pancreatic_tumor_associated_fibroblasts_B0010A_untreated 1069 4 390 23 0 18 158 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_126800830 chr1:27862541-27876317 Sample_02_1268 Bone Im-GCT-4072_G34W unedited_U3 830 2 386 23 0 18 145 THEMIS2,PPP1R8,SCARNA1,RPA2
SE_02_134900274 chr1:27862766-27893048 Sample_02_1349 Leukophereses leukophereses_p411 274 11 856 89 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_139300167 chr1:27862773-27892225 Sample_02_1393 Lymph node anaplastic large cell lymphoma cells_ALK+#54 167 11 839 87 2 53 1075 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_142900229 chr1:27862811-27895287 Sample_02_1429 Blood GM12878_WT 229 9 910 99 3 55 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B,FAM76A,STX12
SE_02_058001026 chr1:27862857-27870664 Sample_02_0580 Blood HEL_sgSIK3e4 1026 2 224 11 0 3 0 PPP1R8,SCARNA1,THEMIS2,RPA2
SE_02_149400248 chr1:27862857-27892406 Sample_02_1494 Other monocyte-derived dendritic cells_0h 248 13 840 87 2 53 1093 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_122400098 chr1:27862867-27900809 Sample_02_1224 Bone marrow normal plasma cell 98 14 1073 121 4 60 1242 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_149600300 chr1:27862869-27892509 Sample_02_1496 Other monocyte-derived dendritic cells_R848_24h 300 14 841 88 2 53 1095 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_109900932 chr1:27863160-27870230 Sample_02_1099 Haematopoietic and lymphoid tissue bone marrow K562_DMSO_noIFNG 932 3 209 11 0 3 0 PPP1R8,SCARNA1,THEMIS2,RPA2
SE_02_073600303 chr1:27863228-27892125 Sample_02_0736 Blood Pt24_leukemia cell_THZ1 303 11 824 87 2 52 1067 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_045600589 chr1:27863382-27895113 Sample_02_0456 Th17 lymphocytes Th17-IL-10- Day 0 589 7 893 99 3 53 1172 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_149500118 chr1:27863506-27886321 Sample_02_1495 Other monocyte-derived dendritic cells_R848_1h 118 11 666 52 1 50 922 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_048300170 chr1:27864226-27892211 Sample_02_0483 Bone marrow HSCe_22y_CD34+,CD38-,Lineage- 170 7 798 85 2 51 1074 RPA2,THEMIS2,SCARNA1,PPP1R8,SMPDL3B
SE_02_104400219 chr1:27864284-27888946 Sample_02_1044 Peripheral blood CD4+ cells_CTCL409 219 7 710 67 2 49 1000 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_074101017 chr1:27874392-27885846 Sample_02_0741 Muscle RH30 1017 8 364 34 1 39 714 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_080500029 chr1:27876338-27886375 Sample_02_0805 Brain 2223_GBM 29 3 308 30 1 34 792 THEMIS2,SCARNA1,PPP1R8,SMPDL3B,RPA2
SE_02_131600637 chr1:27883582-27892946 Sample_02_1316 Brain hMGLs_TREM2-R47H 637 4 248 42 2 1 358 RPA2,THEMIS2,SCARNA1,SMPDL3B
SE_02_131200482 chr1:27883858-27893163 Sample_02_1312 Brain hMGLs_WT 482 4 249 43 2 1 358 RPA2,THEMIS2,SCARNA1,SMPDL3B
Genomic distribution of SEs associated with THEMIS2
Genome Browser

The strength of the tissue affected by the gene

Expression of THEMIS2

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)