SEdb 2.0
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Gene overview

Strategies/Algorithm: overlap Ensembl ID: ENSG00000136237
Gene: RAPGEF5 Gene type: protein_coding
Strand: - External links:
Genomic region: chr7:22118236-22357154 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_120300576 chr7:22102523-22120257 Sample_02_1203 Brain NB1 576 8 594 24 4 31 207 RAPGEF5,CDCA7L
SE_02_117300224 chr7:22102812-22220917 Sample_02_1173 Brain GBM01 224 53 3253 181 11 413 1215 RAPGEF5
SE_02_121300406 chr7:22102970-22158609 Sample_02_1213 Brain GBM31 406 22 1636 87 6 164 917 RAPGEF5,CDCA7L
SE_02_120500063 chr7:22103603-22234820 Sample_02_1205 Brain NB3 63 68 3580 193 11 443 1244 RAPGEF5
SE_02_035000139 chr7:22106378-22157935 Sample_02_0350 Dorsolateral prefrontal cortex dorsolateral-prefrontal-cortex 139 16 1521 82 5 164 908 RAPGEF5,CDCA7L
SE_02_151900755 chr7:22109821-22141764 Sample_02_1519 Umbilical vein HUVEC_Scr_IL1beta 755 21 903 24 3 89 656 RAPGEF5,CDCA7L
SE_02_079900157 chr7:22109866-22126524 Sample_02_0799 Brain MESMN1 157 10 515 15 2 43 484 RAPGEF5,CDCA7L
SE_02_083200555 chr7:22109951-22130641 Sample_02_0832 Umblical vein HUVECs_TNF30min 555 14 634 21 2 59 504 RAPGEF5,CDCA7L
SE_02_031900437 chr7:22110414-22167978 Sample_02_0319 Neuroblastoma NB-EBc1 437 7 1650 106 5 200 1020 RAPGEF5,CDCA7L
SE_02_130800137 chr7:22110569-22131894 Sample_02_1308 Artery Pulmonary artery endothelial cells_caMEK5 137 5 639 21 2 61 547 RAPGEF5,CDCA7L
SE_02_130900319 chr7:22110579-22130068 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 319 3 601 20 2 53 484 RAPGEF5,CDCA7L
SE_02_105800421 chr7:22110583-22147372 Sample_02_1058 Bone A673_SA2 Rescue 421 21 1047 29 3 114 731 RAPGEF5,CDCA7L
SE_02_105900460 chr7:22110683-22153908 Sample_02_1059 Bone A673_WT 460 15 1241 50 4 141 771 RAPGEF5,CDCA7L
SE_02_147300461 chr7:22110683-22153908 Sample_02_1473 Bone A-673 461 15 1241 50 4 141 771 RAPGEF5,CDCA7L
SE_02_156400001 chr7:22110840-22226783 Sample_02_1564 Gastrointestinal Stromal GIST-430 1 56 3136 170 9 431 1215 RAPGEF5
SE_02_058600055 chr7:22111777-22230294 Sample_02_0586 Chordal patient-derived chordoma MGH_4 55 39 3209 174 9 431 1215 RAPGEF5
SE_02_154600003 chr7:22120955-22295997 Sample_02_1546 Gastrointestinal Stromal GIST-430/654 3 53 4670 264 12 532 1025 RAPGEF5
SE_02_030800359 chr7:22126845-22156052 Sample_02_0308 Neuroblastoma SJNB1 359 4 807 43 2 113 341 RAPGEF5,CDCA7L
SE_02_003901228 chr7:22128437-22144145 Sample_02_0039 Embryo AFG 1228 3 400 8 1 40 172 RAPGEF5,CDCA7L
SE_02_004000171 chr7:22128952-22154975 Sample_02_0040 Embryo PFG 171 3 712 36 2 95 341 RAPGEF5,CDCA7L
SE_01_009500881 chr7:22129977-22155026 Sample_01_0095 Embryo neuroepithelial stem cell stably expressing HES5 originated from H9 881 5 680 34 2 95 341 RAPGEF5,CDCA7L
SE_02_154400186 chr7:22152031-22194705 Sample_02_1544 Gastrointestinal Stromal GIST-882 186 16 1144 85 3 148 392 RAPGEF5
SE_02_156000489 chr7:22166263-22221382 Sample_02_1560 Gastrointestinal Stromal GIST-9_PDGFRA e18 489 29 1412 63 4 230 239 RAPGEF5
SE_02_127800145 chr7:22171301-22217427 Sample_02_1278 Chordoma UCH1_DMSO_48h 145 12 1166 52 4 172 143 RAPGEF5
SE_02_050400378 chr7:22174443-22214383 Sample_02_0504 Esophagus KYSE510_1 378 18 988 38 4 154 143 RAPGEF5
SE_02_090000676 chr7:22174786-22222718 Sample_02_0900 Heart left ventricle_LV1452 676 21 1224 57 4 195 195 RAPGEF5
SE_02_022800400 chr7:22180442-22216703 Sample_02_0228 Oesophagus KYSE510 400 3 889 41 4 158 143 RAPGEF5
SE_01_008800991 chr7:22182001-22225146 Sample_01_0088 Tibial nerve tibial-nerve 991 7 1080 53 4 185 195 RAPGEF5,CDCA7L
SE_02_121300603 chr7:22182252-22223787 Sample_02_1213 Brain GBM31 603 17 1041 51 4 182 195 RAPGEF5
SE_02_120400662 chr7:22184619-22231647 Sample_02_1204 Brain NB2 662 21 1194 56 4 194 224 RAPGEF5
SE_02_120300550 chr7:22184841-22229905 Sample_02_1203 Brain NB1 550 20 1137 55 4 190 195 RAPGEF5
SE_01_002100582 chr7:22189075-22196145 Sample_01_0021 Skin bipolar-neuron 582 1 170 6 1 52 143 RAPGEF5,CDCA7L
SE_02_053300780 chr7:22193366-22229825 Sample_02_0533 Blood vessel Circle of Willis_54y 780 16 926 48 3 169 168 RAPGEF5,CDCA7L
SE_02_053400590 chr7:22193368-22223076 Sample_02_0534 Blood vessel Circle of Willis_60y 590 17 753 43 3 155 168 RAPGEF5
SE_02_094900480 chr7:22193787-22221816 Sample_02_0949 Umbilical artery HUAEC_WT 480 10 715 41 3 139 105 RAPGEF5
SE_02_090800940 chr7:22200563-22224501 Sample_02_0908 Heart left ventricle_DCM_LV1262 940 9 591 38 1 109 52 RAPGEF5
SE_01_009000673 chr7:22202541-22225338 Sample_01_0090 Lung upper-lobe-of-left-lung 673 3 565 38 1 104 52 RAPGEF5
SE_00_000301140 chr7:22202919-22223652 Sample_00_0003 Adrenal gland adrenal-gland_97d 1140 4 521 36 1 103 52 RAPGEF5,CDCA7L
SE_02_090601252 chr7:22203773-22222830 Sample_02_0906 Heart left ventricle_DCM_LV1072 1252 7 490 35 1 103 52 RAPGEF5
SE_02_089900933 chr7:22203894-22222717 Sample_02_0899 Heart left ventricle_LV1400 933 15 484 35 1 101 52 RAPGEF5
SE_02_091400612 chr7:22204202-22222424 Sample_02_0914 Heart left ventricle_DCM_LV1342 612 11 470 35 1 100 52 RAPGEF5
SE_02_090901119 chr7:22204458-22221970 Sample_02_0909 Heart left ventricle_DCM_LV1264 1119 12 452 34 1 100 52 RAPGEF5
SE_02_091500606 chr7:22204732-22224281 Sample_02_0915 Heart left ventricle_DCM_LV1371 606 13 492 35 1 90 52 RAPGEF5
SE_02_089500731 chr7:22204932-22221670 Sample_02_0895 Heart left ventricle_LV1259 731 8 436 33 1 88 52 RAPGEF5
SE_02_091801047 chr7:22205295-22221801 Sample_02_0918 Heart left ventricle_DCM_LV1437 1047 9 436 33 1 87 52 RAPGEF5
SE_02_091600772 chr7:22205420-22221981 Sample_02_0916 Heart left ventricle_DCM_LV1392 772 10 437 34 1 87 52 RAPGEF5
SE_02_130800030 chr7:22205631-22221836 Sample_02_1308 Artery Pulmonary artery endothelial cells_caMEK5 30 4 429 33 1 87 52 RAPGEF5
SE_02_092001094 chr7:22205658-22222007 Sample_02_0920 Heart left ventricle_DCM_LV1535 1094 7 433 34 1 87 52 RAPGEF5
SE_02_154400208 chr7:22207339-22230766 Sample_02_1544 Gastrointestinal Stromal GIST-882 208 9 624 38 1 96 61 RAPGEF5
SE_02_152200675 chr7:22207421-22231775 Sample_02_1522 Skin A375 RTKi 675 8 648 39 1 96 81 RAPGEF5
SE_02_156901415 chr7:22207627-22221687 Sample_02_1569 Endothelial Endothelial cells 1415 3 387 31 1 80 52 RAPGEF5
SE_02_130900144 chr7:22208077-22221896 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 144 2 384 29 1 77 52 RAPGEF5
SE_01_002600449 chr7:22213053-22221605 Sample_01_0026 Umbilical vein endothelial-cell-of-umbilical-vein 449 1 246 19 0 54 52 RAPGEF5
SE_02_062000354 chr7:22213263-22221601 Sample_02_0620 Aortic Aortic Endothelial Cells_DF 354 8 244 19 0 54 52 RAPGEF5
SE_01_002500294 chr7:22235950-22304376 Sample_01_0025 Haematopoietic and lymphoid tissue blood DND-41 294 11 1875 106 5 124 74 RAPGEF5
SE_02_120500304 chr7:22286926-22400022 Sample_02_1205 Brain NB3 304 60 3166 174 7 360 307 RAPGEF5
SE_02_130200046 chr7:22289431-22405300 Sample_02_1302 Lymphoma RL DMSO 46 33 3243 179 7 383 307 RAPGEF5
SE_01_009600032 chr7:22303293-22405519 Sample_01_0096 B-cell lymphoma DOHH2 32 28 2853 160 7 370 264 RAPGEF5
SE_02_031400065 chr7:22316998-22413007 Sample_02_0314 Neuroblastoma SK-N-FI 65 10 2747 176 5 330 166 RAPGEF5
SE_02_031200482 chr7:22317085-22379767 Sample_02_0312 Neuroblastoma SK-N-BE_2-C 482 6 1746 113 4 239 166 RAPGEF5
SE_02_110900157 chr7:22317223-22413792 Sample_02_1109 Brain SK-N-FI 157 38 2758 180 5 327 166 RAPGEF5
SE_02_128300391 chr7:22318131-22347275 Sample_02_1283 Lung NCI-H2107_p8-15 391 10 854 41 1 93 7 RAPGEF5
SE_02_029700479 chr7:22318973-22357991 Sample_02_0297 Neuroblastoma CLB-CAR 479 4 1082 61 1 161 133 RAPGEF5
SE_02_130400009 chr7:22319067-22460723 Sample_02_1304 Lymphoma RL_lenalidomide_tazemetostat 9 46 3997 284 8 384 269 RAPGEF5,STEAP1B
SE_02_069800212 chr7:22319526-22373511 Sample_02_0698 Lung NCI-H1048-cas9_sgPOU2F3 212 22 1488 88 2 204 133 RAPGEF5
SE_02_022800491 chr7:22319631-22359513 Sample_02_0228 Oesophagus KYSE510 491 5 1111 62 1 156 133 RAPGEF5
SE_02_079800293 chr7:22319913-22357885 Sample_02_0798 Brain 1919 293 9 1053 59 1 150 133 RAPGEF5
SE_02_153300563 chr7:22319974-22347447 Sample_02_1533 Lung purified primary alveolar epithelial type 2 cells 563 7 806 39 0 84 0 RAPGEF5
SE_02_151200618 chr7:22319978-22347447 Sample_02_1512 Lung Purified AT2 cells 618 5 806 39 0 84 0 RAPGEF5
SE_02_156701208 chr7:22320174-22343314 Sample_02_1567 iPSCs CiPSC 1208 5 692 34 0 56 0 RAPGEF5
SE_02_069700106 chr7:22322193-22379006 Sample_02_0697 Lung NCI-H1048-cas9_sgHROSA 106 36 1591 107 3 219 133 RAPGEF5
SE_02_068500501 chr7:22322566-22379112 Sample_02_0685 Lung NCI-H1048_no infection 501 23 1584 106 3 219 133 RAPGEF5
SE_02_106500134 chr7:22322829-22388522 Sample_02_1065 Lymphoma KARPAS-422_DMSO_8d 134 22 1869 122 3 240 133 RAPGEF5
SE_02_130300012 chr7:22323033-22453652 Sample_02_1303 Lymphoma RL_tazemetostat 12 41 3694 276 7 370 269 RAPGEF5,STEAP1B
SE_02_139700168 chr7:22323146-22378545 Sample_02_1397 Stomach SNU16 168 14 1554 106 3 219 133 RAPGEF5
SE_02_115300288 chr7:22323311-22403542 Sample_02_1153 Lymphoma RL_R1446C_gRNA1 288 17 2300 139 4 290 133 RAPGEF5
SE_02_028800339 chr7:22324010-22403083 Sample_02_0288 Tonsil CB5_H3K27Ac 339 11 2269 138 4 285 133 RAPGEF5
SE_00_002000534 chr7:22325855-22360479 Sample_00_0020 Large intestine large-intestine_108d 534 5 986 60 1 145 133 RAPGEF5
SE_00_003601033 chr7:22326014-22360360 Sample_00_0036 Small intestine small-intestine_108days 1033 7 975 60 1 145 133 RAPGEF5
SE_01_008200498 chr7:22329294-22362302 Sample_01_0082 Right lobe of liver right-lobe-of-liver 498 5 941 52 1 148 133 RAPGEF5
SE_02_032500236 chr7:22329365-22360571 Sample_02_0325 Liver hepatocytes_d1 236 5 895 51 1 142 133 RAPGEF5
SE_02_115400154 chr7:22330226-22405273 Sample_02_1154 Lymphoma RL_R1446C_gRNA1_KDAC001 154 13 2150 129 4 297 133 RAPGEF5
SE_02_071000830 chr7:22332246-22352445 Sample_02_0710 Pancreas hN34_organoid 830 7 590 37 1 76 0 RAPGEF5
SE_01_010101357 chr7:22332289-22373607 Sample_01_0101 Pancreas pancreas_54y 1357 8 1135 73 2 177 133 RAPGEF5
SE_02_050400586 chr7:22333326-22359061 Sample_02_0504 Esophagus KYSE510_1 586 12 709 46 1 123 133 RAPGEF5
SE_02_031900214 chr7:22336299-22399064 Sample_02_0319 Neuroblastoma NB-EBc1 214 9 1773 112 4 254 133 RAPGEF5
SE_02_030000203 chr7:22338113-22395753 Sample_02_0300 Neuroblastoma CLB-PE 203 6 1595 104 3 224 133 RAPGEF5
SE_02_031500169 chr7:22338753-22379353 Sample_02_0315 Neuroblastoma TR14 169 5 1091 84 3 179 133 RAPGEF5
SE_02_032600448 chr7:22339001-22362300 Sample_02_0326 Liver hepatocytes_d3 448 4 603 38 1 113 133 RAPGEF5
SE_02_020700370 chr7:22345453-22361058 Sample_02_0207 Stomach FU97 370 4 380 30 1 87 133 RAPGEF5
SE_02_012100121 chr7:22353948-22403810 Sample_02_0121 Haematopoietic and lymphoid tissue SUDHL-4 121 4 1411 87 3 197 133 RAPGEF5
Genomic distribution of SEs associated with RAPGEF5
Genome Browser

The strength of the tissue affected by the gene

Expression of RAPGEF5

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)