SEdb 2.0
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Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000091879
Gene: ANGPT2 Gene type: protein_coding
Strand: - External links:
Genomic region: chr8:6499632-6563409 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_111900252 chr8:6497452-6576054 Sample_02_1119 Blood KBM7 252 22 3465 108 17 238 862 ANGPT2,MCPH1,MIR8055
SE_02_154300068 chr8:6497664-6544236 Sample_02_1543 Gastrointestinal Stromal GIST-48 68 14 2123 70 13 103 738 ANGPT2,MCPH1
SE_02_080800033 chr8:6501720-6650507 Sample_02_0808 Ovary RMG1_ARID1A KO 33 96 6790 209 37 345 906 ANGPT2,MCPH1,MCPH1-AS1,MIR8055
SE_02_044500481 chr8:6514183-6645411 Sample_02_0445 Lung lung metastasis from primary osteosarcoma tumor M10 481 45 6012 178 32 318 532 ANGPT2,MCPH1,MCPH1-AS1,MIR8055
SE_02_057600801 chr8:6515216-6576125 Sample_02_0576 Blood HEL_sgLKB1e2 801 19 2679 76 14 199 277 ANGPT2,MCPH1,MIR8055
SE_02_058000986 chr8:6515405-6574938 Sample_02_0580 Blood HEL_sgSIK3e4 986 20 2631 74 14 199 277 ANGPT2,MCPH1,MIR8055
SE_02_053400087 chr8:6516559-6611076 Sample_02_0534 Blood vessel Circle of Willis_60y 87 33 4232 81 17 267 277 ANGPT2,MCPH1,MIR8055
SE_02_053300158 chr8:6516824-6613663 Sample_02_0533 Blood vessel Circle of Willis_54y 158 40 4370 87 19 265 277 ANGPT2,MCPH1,MIR8055
SE_02_059400445 chr8:6523135-6621099 Sample_02_0594 iPSC-derived neural progenitors 445 21 4429 101 19 255 201 ANGPT2,MCPH1,MCPH1-AS1,MIR8055
SE_02_017300108 chr8:6526544-6620677 Sample_02_0173 Lung IMR-90_senescent 108 23 4235 96 19 250 201 MCPH1,ANGPT2
SE_02_003900578 chr8:6526668-6577730 Sample_02_0039 Embryo AFG 578 8 2222 60 13 173 201 MCPH1,ANGPT2
SE_02_094900506 chr8:6526727-6572122 Sample_02_0949 Umbilical artery HUAEC_WT 506 18 2004 57 13 166 201 ANGPT2,MCPH1
SE_02_103000093 chr8:6527290-6613502 Sample_02_1030 Colon DKO 93 42 3873 73 18 243 201 ANGPT2,MCPH1,MIR8055
SE_02_130900359 chr8:6527591-6571406 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 359 6 1925 55 13 144 180 ANGPT2,MCPH1
SE_02_095001216 chr8:6527842-6570860 Sample_02_0950 Umbilical vein HUVEC_WT 1216 14 1899 53 13 135 164 ANGPT2,MCPH1
SE_02_156900532 chr8:6527848-6571923 Sample_02_1569 Endothelial Endothelial cells 532 5 1940 56 13 151 164 ANGPT2,MCPH1
SE_02_005300148 chr8:6527903-6561670 Sample_02_0053 Colon DKO1 148 9 1507 30 10 79 40 MCPH1,ANGPT2
SE_02_130800539 chr8:6527927-6571500 Sample_02_1308 Artery Pulmonary artery endothelial cells_caMEK5 539 5 1919 55 13 141 164 ANGPT2,MCPH1
SE_02_156800719 chr8:6528306-6571594 Sample_02_1568 Heart Cardiac progenitor cells 719 5 1899 53 13 142 164 ANGPT2,MCPH1
SE_02_005500900 chr8:6531373-6561398 Sample_02_0055 Lung IMR-90_Nutlin-3a 900 5 1311 23 8 74 40 MCPH1,ANGPT2
SE_02_005400938 chr8:6531398-6562473 Sample_02_0054 Lung IMR-90_DMSO_1 938 5 1350 23 8 93 44 MCPH1,ANGPT2
SE_02_072700462 chr8:6531588-6606046 Sample_02_0727 Fetal lung IMR90_Etoposide 462 15 3258 59 13 220 164 ANGPT2,MCPH1,MIR8055
SE_02_131100584 chr8:6531648-6611620 Sample_02_1311 Bone marrow HDMSCs 584 19 3531 59 15 225 164 ANGPT2,MCPH1,MIR8055
SE_02_141600755 chr8:6534225-6559868 Sample_02_1416 Brain SF9402 755 4 1131 20 8 58 0 ANGPT2,MCPH1
SE_02_158401459 chr8:6534230-6605664 Sample_02_1584 Brain U87 GBM_Mock 1459 9 3126 56 13 217 124 ANGPT2,MCPH1,MIR8055
SE_01_001900776 chr8:6534558-6562658 Sample_01_0019 Brain and spinal cord astrocyte 776 3 1231 19 8 90 22 MCPH1,ANGPT2
SE_02_055400237 chr8:6534661-6600783 Sample_02_0554 Other Aska shSSX 237 13 2844 53 13 210 124 ANGPT2,MCPH1,MIR8055
SE_00_003100063 chr8:6537917-6605898 Sample_00_0031 Placenta placenta 63 6 3013 50 11 216 124 MCPH1,ANGPT2
SE_01_009301066 chr8:6538461-6598133 Sample_01_0093 Aorta ascending aorta 1066 16 2563 46 11 187 124 ANGPT2,MCPH1,MIR8055
SE_01_010200259 chr8:6539184-6569705 Sample_01_0102 Artery tibial artery 259 12 1345 33 8 118 124 ANGPT2,MCPH1
SE_02_143400275 chr8:6540049-6603319 Sample_02_1434 Trophoblast trophoblast stem cells 275 10 2732 48 8 214 124 ANGPT2,MCPH1,MIR8055
SE_02_143500505 chr8:6540337-6578770 Sample_02_1435 Trophoblast trophoblast stem cells_MSX2_KD 505 5 1625 41 6 157 124 ANGPT2,MCPH1,MIR8055
SE_02_117700463 chr8:6540661-6602681 Sample_02_1177 Brain GBM05 463 10 2672 47 7 207 124 ANGPT2,MCPH1,MIR8055
SE_02_097600277 chr8:6540726-6563610 Sample_02_0976 Brain H3.3K27M-KO_DIPGXIII-c5p5-Rx_R1_cells_h3k27ac 277 6 983 14 4 113 124 ANGPT2,MCPH1
SE_01_011400067 chr8:6540777-6612700 Sample_01_0114 Colon HCT116_encode 67 25 3214 53 10 219 124 ANGPT2,MCPH1,MIR8055
SE_02_044800632 chr8:6542438-6570804 Sample_02_0448 Bone MNNG 632 9 1225 34 4 125 124 ANGPT2,MCPH1
SE_02_042700079 chr8:6544931-6609469 Sample_02_0427 Colon HCT116_shPAF1 79 7 2843 45 7 205 124 MCPH1,ANGPT2
SE_02_042600081 chr8:6545039-6605878 Sample_02_0426 Colon HCT116_NONT 81 7 2657 44 6 201 124 MCPH1,ANGPT2
SE_02_126701250 chr8:6545879-6562104 Sample_02_1267 Bone Im-GCT-4072_G34W 1250 2 704 8 1 54 0 ANGPT2,MCPH1
SE_02_035200133 chr8:6545920-6608500 Sample_02_0352 Colon HCT116 133 12 2747 45 7 191 124 MCPH1,ANGPT2
SE_02_033600671 chr8:6546043-6574255 Sample_02_0336 Haematopoietic and lymphoid tissue SET2 671 3 1199 36 4 120 124 MCPH1,ANGPT2
SE_01_003400125 chr8:6546178-6603934 Sample_01_0034 Colon HCT116 125 7 2504 44 6 190 124 MCPH1,ANGPT2
SE_02_030101016 chr8:6546361-6605932 Sample_02_0301 Neuroblastoma GIMEN 1016 7 2610 44 6 190 124 MCPH1,ANGPT2
SE_01_002600401 chr8:6546555-6571472 Sample_01_0026 Umbilical vein endothelial-cell-of-umbilical-vein 401 3 1076 33 4 107 124 MCPH1,ANGPT2
SE_02_018200677 chr8:6546674-6562564 Sample_02_0182 melanoma LOX-IMVI 677 4 691 8 1 63 16 MCPH1,ANGPT2
SE_02_043700313 chr8:6546802-6600567 Sample_02_0437 Bone 143B 313 18 2293 42 6 183 124 ANGPT2,MCPH1,MIR8055
SE_02_076900335 chr8:6547278-6601863 Sample_02_0769 Ovary HEYA8 335 23 2339 42 6 182 124 ANGPT2,MCPH1,MIR8055
SE_02_108100275 chr8:6547334-6617088 Sample_02_1081 Muscle CTR shCtrl 275 21 3122 64 9 195 124 ANGPT2,MCPH1,MCPH1-AS1,MIR8055
SE_02_075500899 chr8:6553330-6570978 Sample_02_0755 Embryo ES-derived progenitors_DE FOXA2 -/- 899 2 765 29 3 82 124 ANGPT2,MCPH1
SE_02_075200278 chr8:6553523-6573816 Sample_02_0752 Embryo ES-derived progenitors_DE_wild type 278 5 859 32 3 101 124 ANGPT2,MCPH1,MIR8055
SE_02_003801024 chr8:6553603-6571269 Sample_02_0038 Embryo DE 1024 5 756 31 3 88 124 MCPH1,ANGPT2
SE_01_009500831 chr8:6554512-6577678 Sample_01_0095 Embryo neuroepithelial stem cell stably expressing HES5 originated from H9 831 4 964 32 3 103 124 ANGPT2,MCPH1,MIR8055
SE_02_055000030 chr8:6556581-6611661 Sample_02_0550 Other Aska-BAF47KO1 shCt 30 9 2434 40 7 174 124 ANGPT2,MCPH1,MIR8055
SE_02_055100034 chr8:6557343-6610779 Sample_02_0551 Other Aska-BAF47KO1 shSSX 34 5 2349 39 6 173 124 ANGPT2,MCPH1,MIR8055
SE_02_049300069 chr8:6557885-6572821 Sample_02_0493 Islets differentiated hESCs Early pancreatic progenitor cells 69 4 613 27 3 95 124 ANGPT2,MCPH1,MIR8055
SE_02_049500226 chr8:6557960-6571760 Sample_02_0495 Islets differentiated hESCs Early LSD1 inhibition PP2 226 2 569 27 3 93 124 ANGPT2,MCPH1
SE_02_049400454 chr8:6558325-6571494 Sample_02_0494 Islets differentiated hESCs Late pancreatic progenitor cells 454 2 544 26 3 83 124 ANGPT2,MCPH1
SE_02_052500791 chr8:6558978-6570580 Sample_02_0525 Pancreas iPS derived pancreatic precursor cells_Lane1 791 3 489 24 3 77 124 ANGPT2,MCPH1
SE_02_016900083 chr8:6558980-6651795 Sample_02_0169 Prostate LNCaP_R1881 83 10 4241 144 24 212 313 MCPH1,ANGPT2
SE_02_017000168 chr8:6559179-6634229 Sample_02_0170 Prostate LNCaP_R1881_DOX 168 7 3424 99 17 202 221 MCPH1,ANGPT2
SE_02_005300163 chr8:6575597-6603340 Sample_02_0053 Colon DKO1 163 5 1231 7 2 70 0 MCPH1,ANGPT2
SE_02_040900083 chr8:6584586-6630035 Sample_02_0409 Kidney G401_NoDox 83 6 2191 56 10 81 97 MCPH1,ANGPT2
SE_02_040800106 chr8:6584665-6620868 Sample_02_0408 Kidney G401_Dox 106 6 1722 36 6 56 0 MCPH1,ANGPT2
SE_02_144600317 chr8:6584961-6600976 Sample_02_1446 Adipose SW872_TAZ_CAMTA1 317 3 703 4 2 38 0 MCPH1,MIR8055,ANGPT2
SE_02_039500509 chr8:6592554-6605807 Sample_02_0395 Mammary gland BT-549 509 2 652 5 0 32 0 MCPH1,ANGPT2
SE_02_016200290 chr8:6597921-6603378 Sample_02_0162 Prostate C4-2B_vehicle_24h 290 4 282 4 0 29 0 MCPH1,ANGPT2
SE_02_016300227 chr8:6598118-6602692 Sample_02_0163 Prostate C4-2B_SR2211_24h 227 3 228 3 0 26 0 MCPH1,ANGPT2
SE_02_019700356 chr8:6598149-6603480 Sample_02_0197 Stomach SNU1750 356 5 268 4 0 29 0 MCPH1,ANGPT2
SE_02_003900556 chr8:6598368-6624463 Sample_02_0039 Embryo AFG 556 5 1345 40 5 47 97 MCPH1,ANGPT2
Genomic distribution of SEs associated with ANGPT2
Genome Browser

The strength of the tissue affected by the gene

Expression of ANGPT2

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)