What is ATACdb?
Here, we developed a comprehensive human chromatin accessibility database
), with the aim of providing a large amount of publicly available resources on human chromatin accessibility data, and to annotate and illustrate potential roles in a tissue/cell type-specific manner.
The current version of ATACdb documented a total of 52,078,883
regions from over 1,400
chromatin accessibility ATAC-seq samples. These samples have been manually curated from more than 2,200 chromatin accessibility samples associated with ATAC-seq data
from NCBI GEO/SRA database. ATACdb provides a quality assurance process
including four quality control (QC) metrics. Moreover, ATACdb provides other detailed (epi) genetic annotation information in chromatin accessibility regions, including super-enhancers, typical enhancers, TFs, common SNPs, risk SNPs, eQTLs, LD SNPs, DNA methylation sites, 3D chromatin interactions and TADs
. ATACdb provides accurate inference of TF footprints
within chromatin accessibility regions. ATACdb is a powerful platform that provides the most comprehensive accessible chromatin data, QC, TF footprint and various other annotations.