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Gene overview

Strategies/Algorithm: lasso Ensembl ID: ENSG00000167468
Gene: GPX4 Gene type: protein_coding
Strand: + External links:
Genomic region: chr19:1103926-1106791 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_098901776 chr19:1016385-1038814 Sample_02_0989 Kidney kidney cortex_WT 1776 8 766 140 1 45 1191 TMEM259,RNU6-1,RNU6-9,CNN2,HMHA1,ABCA7,GRIN3B,WDR18,GPX4,SBNO2,ARID3A
SE_02_060501217 chr19:1025931-1029776 Sample_02_0605 Skin Skin Fibroblast_DMSO 1217 2 91 14 0 24 240 CNN2,HMHA1,ABCA7,GRIN3B,TMEM259,WDR18,GPX4,POLR2E,ARID3A
SE_02_059100138 chr19:1066303-1088751 Sample_02_0591 PBMCs adult CD4+CD25-CD45RA+CD27+ naive T cells 138 8 887 82 1 138 3173 HMHA1,POLR2E,SBNO2,ABCA7,GPX4,TMEM259,CNN2
SE_01_010400141 chr19:1133776-1217695 Sample_01_0104 Lung upper lobe of left lung 141 21 2905 139 3 84 1104 STK11,SBNO2,POLR2E,GPX4,CBARP,MIDN,ATP5D,HMHA1,CIRBP,C19orf24,C19orf26
SE_00_005500125 chr19:1150478-1219068 Sample_00_0055 Spleen spleen 34y 125 23 2391 112 3 83 964 STK11,SBNO2,GPX4,CBARP,MIDN,ATP5D,CIRBP,ARID3A,HMHA1,C19orf24,ABCA7,TMEM259,C19orf26
SE_02_093500189 chr19:1153826-1177903 Sample_02_0935 Retinal Pigmented Epithelial RPE188_Con 189 12 863 37 0 32 345 SBNO2,STK11,GPX4,GAMT,RPS15,HMHA1,CIRBP,ATP5D,POLR2E,CNN2,C19orf24,ABCA7,WDR18,C19orf26,MIDN
SE_02_066600240 chr19:1154306-1194842 Sample_02_0666 Prostate RWPE1 Lacz rep1 240 8 1523 79 0 52 230 SBNO2,ATP5D,STK11,CBARP,GPX4,CIRBP,POLR2E,HMHA1,SHC2,C19orf24,C19orf26,MIDN
SE_02_094100106 chr19:1154373-1184636 Sample_02_0941 Brain T98G 106 8 1107 54 0 48 209 SBNO2,STK11,GPX4,GAMT,CIRBP,EFNA2,ATP5D,POLR2E,HMHA1,C19orf24,WDR18
SE_01_011700302 chr19:1154590-1177886 Sample_01_0117 Lung fibroblast of lung 302 4 823 37 0 25 158 SBNO2,STK11,GPX4,CIRBP,HMHA1,ATP5D,POLR2E,C19orf24,C19orf26
SE_02_088000759 chr19:1154649-1184491 Sample_02_0880 Ovary SVOG3e cells_noDox_transduced_V5-FOXL2_WT 759 6 1083 54 0 48 158 SBNO2,STK11,GPX4,CIRBP,ATP5D,HMHA1,C19orf24
SE_02_094700016 chr19:1154661-1217196 Sample_02_0947 Tongue Cal27 16 7 2128 104 3 75 664 STK11,SBNO2,ATP5D,CBARP,MIDN,GPX4,CIRBP,POLR2E,C19orf24,NDUFS7,C19orf26
SE_02_151400485 chr19:1154707-1190107 Sample_02_1514 Lung Differentiated AT1-like cells 485 9 1300 71 0 48 158 SBNO2,STK11,CBARP,CIRBP,HMHA1,ATP5D,GPX4,POLR2E,C19orf24,C19orf26
SE_02_088200631 chr19:1154773-1184542 Sample_02_0882 Ovary SVOG3e_cells_noDox_transduced with V5-FOXL2 C134W 631 6 1086 54 0 48 158 SBNO2,STK11,GPX4,CIRBP,ATP5D,HMHA1,C19orf24
SE_02_087901041 chr19:1154783-1184407 Sample_02_0879 Ovary SVOG3e cells_Dox_12h_control 1041 6 1079 54 0 48 158 SBNO2,STK11,GPX4,CIRBP,ATP5D,HMHA1,C19orf24
SE_02_088100691 chr19:1154806-1208234 Sample_02_0881 Ovary SVOG3e cells_Dox_12h_transduced_V5-FOXL2_WT 691 8 1818 90 3 73 664 STK11,SBNO2,ATP5D,CBARP,MIDN,GPX4,CIRBP,HMHA1,C19orf24
SE_02_088300839 chr19:1154943-1184409 Sample_02_0883 Ovary SVOG3e_cells_Dox_12h_transduced with V5-FOXL2 C134W 839 5 1066 54 0 48 158 SBNO2,STK11,GPX4,CIRBP,ATP5D,HMHA1,C19orf24
SE_02_087801009 chr19:1154948-1184787 Sample_02_0878 Ovary SVOG3e cells_noDox_control 1009 6 1083 55 0 48 158 SBNO2,STK11,GPX4,CIRBP,ATP5D,HMHA1,C19orf24
SE_02_151200398 chr19:1155229-1184375 Sample_02_1512 Lung Purified AT2 cells 398 6 1057 53 0 48 158 SBNO2,STK11,CIRBP,HMHA1,ATP5D,GPX4,POLR2E,C19orf24,C19orf26
SE_02_153300417 chr19:1155305-1184382 Sample_02_1533 Lung purified primary alveolar epithelial type 2 cells 417 8 1057 53 0 48 158 SBNO2,STK11,CIRBP,HMHA1,ATP5D,GPX4,POLR2E,C19orf24,C19orf26
SE_02_058400109 chr19:1161091-1219406 Sample_02_0584 Lung H1299 WT 109 23 1939 103 3 82 854 STK11,SBNO2,CIRBP,ATP5D,CBARP,MIDN,GAMT,GPX4,HMHA1,EFNA2,POLR2E,MED16,C19orf24,ABCA7,WDR18,NDUFS7,REEP6,C19orf26
SE_02_098700358 chr19:1161610-1209405 Sample_02_0987 Blood K562_Control_1 358 11 1592 83 3 73 664 STK11,SBNO2,ATP5D,CBARP,MIDN,CIRBP,C19orf26,POLR2E,GPX4,HMHA1,C19orf24
SE_02_158200548 chr19:1165601-1194850 Sample_02_1582 Renal OS-RC-2 548 8 1091 64 0 48 158 SBNO2,STK11,ATP5D,CBARP,HMHA1,GPX4,C19orf24,C19orf26
SE_02_094600093 chr19:1167895-1195048 Sample_02_0946 Tongue HN12 93 4 1039 61 0 48 158 SBNO2,STK11,ATP5D,CBARP,GPX4,CIRBP,POLR2E,C19orf24,NDUFS7,C19orf26
SE_02_112000112 chr19:1168537-1194888 Sample_02_1120 Neonatal foreskin keratinocytes_CTR 112 14 1009 59 0 47 158 SBNO2,STK11,ATP5D,CBARP,GPX4
SE_02_113900499 chr19:1168724-1217135 Sample_02_1139 Retinal Pigmented Epithelial RPE1-anaphase/telophase 499 11 1632 84 3 74 664 STK11,SBNO2,ATP5D,CBARP,MIDN,GAMT,RPS15,HMHA1,CIRBP,GPX4,POLR2E,CNN2,C19orf24,ABCA7,WDR18,C19orf26
SE_02_113800576 chr19:1168774-1216923 Sample_02_1138 Retinal Pigmented Epithelial RPE1-prometaphase 576 11 1620 83 3 74 664 STK11,SBNO2,ATP5D,CBARP,MIDN,GAMT,RPS15,HMHA1,CIRBP,GPX4,POLR2E,CNN2,C19orf24,ABCA7,WDR18,C19orf26
SE_02_151300440 chr19:1172281-1190433 Sample_02_1513 Lung Transitional AT2->1 cells 440 5 678 42 0 44 158 SBNO2,STK11,CBARP,CIRBP,ATP5D,GPX4,POLR2E,C19orf24,C19orf26
SE_04_000900118 chr19:1239599-1268258 Sample_04_0009 Lung A549 118 4 1038 27 1 300 2510 CIRBP-AS1,ATP5D,MIDN,C19ORF24,CIRBP,STK11,CBARP,EFNA2,GPX4,POLR2E,MUM1,C19orf26
SE_02_107100017 chr19:1239704-1267056 Sample_02_1071 Blood Jurkat_WT 17 7 1006 25 1 283 2283 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,SBNO2,C19orf24,DAZAP1,C19orf26
SE_04_000500070 chr19:1239718-1267135 Sample_04_0005 Lung A549 FOXA2 overexpressed 70 6 1010 26 1 283 2283 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,MUM1,C19orf26
SE_00_004900008 chr19:1243471-1267088 Sample_00_0049 Small intestine small intestine 30y 8 12 900 22 1 257 1997 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,HMHA1,SBNO2,C19orf24,MUM1,REEP6,C19orf26,ADAMTSL5
SE_02_094100065 chr19:1243706-1267129 Sample_02_0941 Brain T98G 65 8 895 22 1 257 1997 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,SBNO2,C19orf24,MUM1,C19orf26
SE_02_112800118 chr19:1244164-1267028 Sample_02_1128 Adipose visceral adipose_CTL_HCTR10 118 14 873 21 1 255 1934 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,GPX4,SBNO2,POLR2E,APC2,C19orf24,NDUFS7,MUM1,C19orf26
SE_02_132100051 chr19:1244202-1267148 Sample_02_1321 Connective Tissue HT1080_FUS-DDIT3 51 8 877 22 1 254 1927 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,HMHA1,GPX4,POLR2E,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_131900007 chr19:1244219-1267216 Sample_02_1319 Connective Tissue HT1080_DDIT3 7 8 880 22 1 254 1922 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,HMHA1,GPX4,POLR2E,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_153100240 chr19:1244388-1265521 Sample_02_1531 Peripheral blood neutrophils_0B9ZK 240 1 820 18 1 229 1877 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_112600041 chr19:1244468-1267178 Sample_02_1126 Adipose visceral adipose_CTL_H425 41 14 864 22 1 254 1847 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,GPX4,SBNO2,POLR2E,APC2,C19orf24,NDUFS7,MUM1,C19orf26
SE_04_001000284 chr19:1244521-1267159 Sample_04_0010 Lung A549 TGFb 284 6 861 22 1 254 1829 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,MUM1,C19orf26
SE_02_132200035 chr19:1244532-1267352 Sample_02_1322 Connective Tissue HT1080_WT 35 4 867 22 1 255 1838 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,HMHA1,GPX4,POLR2E,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_04_000600096 chr19:1244582-1267110 Sample_04_0006 Lung A549 GFP control 96 5 861 22 1 254 1814 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,MUM1,C19orf26
SE_02_132000018 chr19:1244614-1267312 Sample_02_1320 Connective Tissue HT1080_EWS-FLI1 18 8 864 22 1 255 1806 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,HMHA1,GPX4,POLR2E,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_149400297 chr19:1244640-1267042 Sample_02_1494 Other monocyte-derived dendritic cells_0h 297 10 853 21 1 254 1797 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,RPS15,GPX4,SBNO2,C19orf24,MUM1,TMEM259,C19orf26,ADAMTSL5
SE_02_049200434 chr19:1244681-1267553 Sample_02_0492 Pharyng Detroit 562_LPS 434 5 871 22 1 256 1833 CIRBP-AS1,ATP5D,MIDN,C19ORF24,CIRBP,STK11,CBARP,EFNA2,GPX4,APC2,HMHA1,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_049100375 chr19:1244726-1267459 Sample_02_0491 Pharyng Detroit 562-Control 375 6 867 22 1 255 1808 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,APC2,HMHA1,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_04_000300142 chr19:1244769-1267029 Sample_04_0003 Lung A549 TEAD4 shRNA TGFb 142 4 851 21 1 254 1766 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GPX4,POLR2E,MUM1,C19orf26
SE_02_100000163 chr19:1244798-1267136 Sample_02_1000 Brain Lateral temporal lobe_15T_Young 163 10 856 22 1 254 1755 ATP5D,MIDN,C19ORF24,CIRBP,CIRBP-AS1,STK11,CBARP,EFNA2,GAMT,GPX4,SBNO2,C19orf24,TMEM259,REEP6,C19orf26
SE_01_011501297 chr19:1244832-1267085 Sample_01_0115 Skeletal Muscle myotube originated from skeletal muscle myoblast 1297 12 854 21 1 254 1748 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,RPS15,GPX4,POLR2E,APC2,SBNO2,NDUFS7,MUM1
SE_02_158200512 chr19:1244955-1267088 Sample_02_1582 Renal OS-RC-2 512 7 850 21 1 254 1712 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,C19orf24,MUM1,C19orf26
SE_02_087500283 chr19:1247177-1263666 Sample_02_0875 Peripheral blood Peripheral blood-derived mast cells 283 1 632 15 1 219 1697 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,SBNO2,NDUFS7,MUM1,C19orf26
SE_02_120500431 chr19:1247423-1258701 Sample_02_1205 Brain NB3 431 1 458 8 1 176 1562 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,SBNO2,C19orf24,REXO1,REEP6,C19orf25,C19orf26
SE_02_092700216 chr19:1247425-1255334 Sample_02_0927 Peripheral blood neutrophils_US 216 1 311 7 1 153 986 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_144500408 chr19:1247615-1267339 Sample_02_1445 Adipose SW872_TAZ4SA 408 1 707 19 1 250 1708 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,RPS15,GPX4,SBNO2,POLR2E,PCSK4,DAZAP1,ABCA7,MUM1,C19orf26
SE_02_130800870 chr19:1247751-1267041 Sample_02_1308 Artery Pulmonary artery endothelial cells_caMEK5 870 5 685 18 1 246 1697 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,POLR2E,SBNO2,DAZAP1,WDR18,NDUFS7,MUM1,C19orf25,C19orf26
SE_02_094800291 chr19:1247881-1267159 Sample_02_0948 Pharyng Detroit562 291 4 682 19 1 246 1697 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,APC2,HMHA1,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_152900288 chr19:1249812-1265870 Sample_02_1529 Peripheral blood neutrophils_0BC75 288 1 598 13 1 169 1500 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_066600217 chr19:1249856-1267177 Sample_02_0666 Prostate RWPE1 Lacz rep1 217 5 639 17 1 183 1492 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,POLR2E,SBNO2,PCSK4,C19orf24,C19orf26
SE_02_100600069 chr19:1250060-1267030 Sample_02_1006 Brain Lateral temporal lobe_13T_Old 69 8 631 16 1 181 1442 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GAMT,GPX4,SBNO2,C19orf24,TMEM259,REEP6,C19orf26
SE_02_066500170 chr19:1250395-1267167 Sample_02_0665 Prostate RWPE1 Schlap1 rep1 170 8 630 16 0 174 1335 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,POLR2E,SBNO2,PCSK4,C19orf24,C19orf26
SE_02_100700060 chr19:1250417-1273383 Sample_02_1007 Brain Lateral temporal lobe_14T_Old 60 11 849 25 0 244 2460 CIRBP-AS1,CIRBP,MIDN,C19ORF24,ATP5D,STK11,CBARP,EFNA2,GAMT,GPX4,SBNO2,C19orf24,TMEM259,REEP6,C19orf26
SE_02_144400355 chr19:1250423-1267083 Sample_02_1444 Adipose SW872_Empty Vector 355 4 628 14 0 173 1329 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,RPS15,GPX4,SBNO2,POLR2E,PCSK4,DAZAP1,ABCA7,MUM1,C19orf26
SE_02_153000350 chr19:1250426-1265689 Sample_02_1530 Peripheral blood neutrophils_0BA0X 350 1 585 11 0 156 1329 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_120400465 chr19:1250744-1257983 Sample_02_1204 Brain NB2 465 1 329 3 0 87 915 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GPX4,SBNO2,C19orf24,REXO1,REEP6,C19orf25,C19orf26
SE_02_100400121 chr19:1253740-1266968 Sample_02_1004 Brain Lateral temporal lobe_10T_Old 121 4 470 12 0 121 1035 MIDN,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,STK11,CBARP,EFNA2,GAMT,GPX4,SBNO2,C19orf24,TMEM259,REEP6,C19orf26
SE_02_108200139 chr19:1265156-1277060 Sample_02_1082 Retina retina 139 1 404 20 0 103 1609 CIRBP-AS1,CIRBP,C19ORF24,ATP5D,CBARP,MIDN,EFNA2,STK11,GPX4,APC2,C19orf24,TMEM259,C19orf26,ADAMTSL5
SE_00_004900521 chr19:1283221-1291719 Sample_00_0049 Small intestine small intestine 30y 521 3 300 9 1 22 173 EFNA2,C19ORF24,CIRBP,CIRBP-AS1,ATP5D,CBARP,MIDN,GAMT,STK11,RPS15,GPX4,SBNO2,DAZAP1,NDUFS7,MUM1,C19orf26
SE_02_153000783 chr19:905517-918060 Sample_02_1530 Peripheral blood neutrophils_0BA0X 783 1 362 27 1 6 411 KISS1R,R3HDM4,CFD,ARID3A,MED16,ELANE,GPX4,POLR2E,CNN2,GRIN3B
SE_02_152900698 chr19:906264-915993 Sample_02_1529 Peripheral blood neutrophils_0BC75 698 1 281 19 1 2 182 R3HDM4,CFD,ARID3A,KISS1R,MED16,ELANE,GPX4,POLR2E,CNN2,GRIN3B
SE_02_092700304 chr19:906387-916332 Sample_02_0927 Peripheral blood neutrophils_US 304 1 282 19 1 2 182 R3HDM4,CFD,ARID3A,KISS1R,MED16,ELANE,GPX4,POLR2E,CNN2,GRIN3B
SE_02_046501176 chr19:924776-941145 Sample_02_0465 Adipose subcutaneous adipocytes 1176 9 674 25 1 83 592 ARID3A,KISS1R,MED16,R3HDM4,WDR18,GPX4,HMHA1,POLR2E,PRTN3,CNN2,ABCA7,PTBP1
SE_02_093000084 chr19:924952-980995 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 84 24 2122 136 4 153 1408 ARID3A,MED16,GRIN3B,TMEM259,WDR18,R3HDM4,CNN2,KISS1R,HMHA1,GPX4,CFD
Genomic distribution of SEs associated with GPX4
Genome Browser

The strength of the tissue affected by the gene

Expression of GPX4

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)