SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000165533
Gene: TTC8 Gene type: protein_coding
Strand: + External links:
Genomic region: chr14:88824153-88881078 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_031200005 chr14:88719571-89025968 Sample_02_0312 Neuroblastoma SK-N-BE_2-C 5 25 8175 579 73 591 1288 TTC8,EML5
SE_02_034100004 chr14:88772716-89027067 Sample_02_0341 Autonomic ganglia SH-SY5Y_untreat 4 31 6916 459 69 504 1030 TTC8,EML5
SE_02_047100061 chr14:88775310-88876934 Sample_02_0471 Brain Kelly DMSO 61 28 2308 179 26 230 933 TTC8,EML5
SE_02_110000027 chr14:88775653-89041699 Sample_02_1100 Brain COG-N-415 27 104 7271 458 68 560 1030 TTC8,EML5
SE_02_150000003 chr14:88786299-88933333 Sample_02_1500 Brain KELLY_untreat 3 44 3684 312 37 323 993 TTC8,EML5
SE_02_030400022 chr14:88786314-88873866 Sample_02_0304 Neuroblastoma N206 22 8 1997 151 25 223 911 TTC8,EML5
SE_02_030900003 chr14:88786444-88928700 Sample_02_0309 Neuroblastoma SJNB6 3 12 3533 309 37 307 993 TTC8,EML5
SE_02_149900028 chr14:88787263-88857414 Sample_02_1499 Brain BE_2_-C 28 19 1593 124 20 182 736 TTC8,EML5
SE_02_054100033 chr14:88787736-88857427 Sample_02_0541 Brain Kelly_NaiveJQ1 33 13 1579 123 20 182 738 TTC8,EML5
SE_02_025300021 chr14:88788578-88956678 Sample_02_0253 Brain BE2C_DMSO 21 20 4338 344 50 362 993 TTC8,EML5
SE_02_031400031 chr14:88788691-89008814 Sample_02_0314 Neuroblastoma SK-N-FI 31 24 5997 408 68 470 1030 TTC8,EML5
SE_02_054200113 chr14:88788761-88870189 Sample_02_0542 Brain Kelly_ResJQ1 113 23 1852 145 25 205 798 TTC8,EML5
SE_02_054400132 chr14:88789407-88871256 Sample_02_0544 Brain Kelly_ResVeh 132 24 1871 145 25 211 812 TTC8,EML5
SE_02_029700131 chr14:88789597-88879710 Sample_02_0297 Neuroblastoma CLB-CAR 131 9 2064 160 29 231 993 TTC8,EML5
SE_02_110900536 chr14:88805887-88872564 Sample_02_1109 Brain SK-N-FI 536 22 1552 123 24 166 699 TTC8,EML5
SE_02_053900010 chr14:88806653-89042371 Sample_02_0539 Brain SK-N-BE_2_-C_GFP_control 10 83 6607 409 67 508 826 TTC8,EML5
SE_02_007500038 chr14:88806810-88855635 Sample_02_0075 Autonomic ganglia kelly_DMSO_3h 38 6 1135 94 19 121 505 TTC8,EML5
SE_02_054000057 chr14:88806966-88876210 Sample_02_0540 Brain SK-N-BE_2_-C_PI3K_engineered 57 33 1608 125 24 177 729 TTC8,EML5
SE_02_053500011 chr14:88807013-88855058 Sample_02_0535 Brain SK-N-BE_2_-C_naive_vehicle 11 20 1120 94 19 121 505 TTC8,EML5
SE_02_123500250 chr14:88807736-88857041 Sample_02_1235 Brain Neuroblastoma PDX tumour cells 250 18 1150 97 19 124 509 TTC8,EML5
SE_02_030600012 chr14:88814797-88908899 Sample_02_0306 Autonomic ganglia SH-SY5Y 12 6 2290 195 31 218 789 TTC8,EML5
SE_02_029600410 chr14:88815267-88836307 Sample_02_0296 Neuroblastoma CLB-BER-Lud 410 3 487 48 9 52 196 TTC8,EML5
SE_02_110200044 chr14:88815969-89041648 Sample_02_1102 Brain LA-N-5 44 104 6377 391 64 501 826 TTC8,EML5
SE_01_011100023 chr14:88816250-88931957 Sample_01_0111 Brain SK-N-SH 23 37 2982 266 33 263 789 TTC8,EML5
SE_02_031800168 chr14:88816629-88857706 Sample_02_0318 Neuroblastoma NB69 168 4 942 78 16 125 536 TTC8,EML5
SE_02_031300022 chr14:88816733-88856552 Sample_02_0313 Neuroblastoma SK-N-DZ 22 3 909 78 16 115 505 TTC8,EML5
SE_02_029900028 chr14:88816802-88858087 Sample_02_0299 Neuroblastoma CLB-MA 28 4 943 78 16 125 536 TTC8,EML5
SE_02_030300009 chr14:88816959-88913353 Sample_02_0303 Neuroblastoma LAN1 9 8 2350 205 30 219 789 TTC8,EML5
SE_02_124600522 chr14:88817284-88856368 Sample_02_1246 Brain LAN5_ATRA 522 18 897 74 15 115 505 TTC8,EML5
SE_02_025200098 chr14:88817421-88877391 Sample_02_0252 Neuroblastoma IMR5-75-shMYCN-MYCN_high 98 6 1379 108 22 173 744 TTC8,EML5
SE_02_110400189 chr14:88817528-88877445 Sample_02_1104 Brain NB-69 189 16 1378 108 22 173 746 TTC8,EML5
SE_02_042100028 chr14:88817657-88921883 Sample_02_0421 Brain BE2C_3 28 13 2597 233 31 235 789 TTC8,EML5
SE_02_031000076 chr14:88817694-88857644 Sample_02_0310 Neuroblastoma SJNB8 76 5 910 75 15 125 536 TTC8,EML5
SE_02_025100108 chr14:88817730-88857502 Sample_02_0251 Autonomic ganglia SH-SY5Y-MYCN-OFF 108 7 903 75 15 125 536 TTC8,EML5
SE_02_030000037 chr14:88817787-88913918 Sample_02_0300 Neuroblastoma CLB-PE 37 10 2347 209 30 219 789 TTC8,EML5
SE_02_034000098 chr14:88817793-88856860 Sample_02_0340 Brain BE2C_2 98 6 884 75 15 115 505 TTC8,EML5
SE_00_000300920 chr14:88817822-88843589 Sample_00_0003 Adrenal gland adrenal-gland_97d 920 6 583 57 11 65 381 TTC8,EML5
SE_02_031900055 chr14:88817888-88878213 Sample_02_0319 Neuroblastoma NB-EBc1 55 9 1383 111 22 174 789 TTC8,EML5
SE_02_029800129 chr14:88817981-88857638 Sample_02_0298 Neuroblastoma CLB-GA 129 7 899 75 15 125 536 TTC8,EML5
SE_02_031500112 chr14:88818061-88855206 Sample_02_0315 Neuroblastoma TR14 112 6 840 72 15 115 505 TTC8,EML5
SE_02_106300108 chr14:88818468-88856182 Sample_02_1063 Brain CLB-GA-control 108 9 849 72 15 115 505 TTC8,EML5
SE_02_108300168 chr14:88818553-88905175 Sample_02_1083 Macula macula 168 30 2056 170 28 218 789 TTC8,EML5
SE_02_106400072 chr14:88818680-88878280 Sample_02_1064 Brain CLB-GA-Dinaciclib_8h 72 13 1363 108 22 174 789 TTC8,EML5
SE_02_110500946 chr14:88819158-88871193 Sample_02_1105 Brain NBL-S 946 19 1193 96 20 154 608 TTC8,EML5
SE_02_053800053 chr14:88820383-88856308 Sample_02_0538 Brain SK-N-BE_2_-C_resistant_JQ1 53 30 821 67 15 115 505 TTC8,EML5
SE_02_033800147 chr14:88821041-88835930 Sample_02_0338 Neuroblastoma BE2 147 3 333 30 8 51 196 TTC8,EML5
SE_02_033900023 chr14:88821157-88857516 Sample_02_0339 Neuroblastoma NGP 23 7 829 65 15 125 536 TTC8,EML5
SE_02_007600137 chr14:88821160-88854693 Sample_02_0076 Autonomic ganglia SH-SY5Y_DMSO_3h 137 4 768 61 15 115 505 TTC8,EML5
SE_02_030800059 chr14:88821256-88856286 Sample_02_0308 Neuroblastoma SJNB1 59 6 798 64 15 115 505 TTC8,EML5
SE_02_022000022 chr14:88821408-88857471 Sample_02_0220 Brain BE2C_1 22 9 822 65 15 123 536 TTC8,EML5
SE_02_003300602 chr14:88821434-88844264 Sample_02_0033 Pancreas pancreatic-islets-F 602 1 517 49 12 66 400 TTC8,EML5
SE_02_150800005 chr14:88821713-89026432 Sample_02_1508 Brain NGPz_untreat 5 53 5769 367 63 441 826 TTC8,EML5
SE_02_106800021 chr14:88823930-88877757 Sample_02_1068 Brain NGP_ctrl 21 15 1242 95 21 171 759 TTC8,EML5
SE_02_049500811 chr14:88823939-88830283 Sample_02_0495 Islets differentiated hESCs Early LSD1 inhibition PP2 811 2 146 12 2 34 175 TTC8,EML5
SE_02_053600048 chr14:88824330-88855997 Sample_02_0536 Brain SK-N-BE_2_-C_resistant_vehicle 48 12 722 57 14 111 469 TTC8,EML5
SE_02_049800125 chr14:88826078-88879703 Sample_02_0498 Fetal lung IMR90 Senescent_1 125 13 1233 96 23 157 614 TTC8,EML5
SE_02_128800058 chr14:88827177-88857701 Sample_02_1288 Lung NCI-H524_p8-15 58 10 691 56 13 105 361 TTC8,EML5
SE_02_049901321 chr14:88828363-88880117 Sample_02_0499 Fetal lung IMR90 IR Senescence 1321 19 1190 91 22 154 614 TTC8,EML5
SE_02_020900859 chr14:88828711-88879659 Sample_02_0209 Lung MRC-5_MRC5_1DPT 859 10 1171 89 22 154 614 TTC8,EML5
SE_02_050000403 chr14:88829884-88879087 Sample_02_0500 Fetal lung IMR90_#2 403 22 1141 85 19 147 614 TTC8,EML5
SE_02_110300079 chr14:88872283-89041238 Sample_02_1103 Brain NB-1643 79 77 5069 286 43 328 156 TTC8
SE_02_031300039 chr14:88873459-88934221 Sample_02_0313 Neuroblastoma SK-N-DZ 39 6 1717 162 12 103 82 TTC8
SE_02_029600074 chr14:88875719-88957382 Sample_02_0296 Neuroblastoma CLB-BER-Lud 74 11 2374 195 25 132 60 TTC8
SE_02_030400171 chr14:88890263-88933719 Sample_02_0304 Neuroblastoma N206 171 7 1286 121 4 83 0 TTC8
SE_02_123500014 chr14:88890283-89042796 Sample_02_1235 Brain Neuroblastoma PDX tumour cells 14 66 4646 246 35 321 37 TTC8
SE_02_033800168 chr14:88890787-88913302 Sample_02_0338 Neuroblastoma BE2 168 6 617 61 2 38 0 TTC8
SE_02_031900581 chr14:88890796-88934035 Sample_02_0319 Neuroblastoma NB-EBc1 581 9 1286 121 4 83 0 TTC8
SE_02_110900593 chr14:88890833-88961724 Sample_02_1109 Brain SK-N-FI 593 27 2126 163 22 131 0 TTC8
SE_02_106800051 chr14:88890981-88956104 Sample_02_1068 Brain NGP_ctrl 51 17 1947 154 15 119 0 TTC8
SE_02_110400083 chr14:88891048-89008840 Sample_02_1104 Brain NB-69 83 39 3635 219 35 232 37 TTC8
SE_02_110100099 chr14:88891144-89043037 Sample_02_1101 Brain KELLY 99 81 4633 245 35 321 37 TTC8
SE_02_029800157 chr14:88891167-88940106 Sample_02_0298 Neuroblastoma CLB-GA 157 8 1445 123 5 83 0 TTC8
SE_02_106400189 chr14:88891207-88913149 Sample_02_1064 Brain CLB-GA-Dinaciclib_8h 189 9 604 59 2 38 0 TTC8
SE_02_110800174 chr14:88891386-89009461 Sample_02_1108 Brain SK-N-BE_2_-C 174 42 3647 220 35 232 37 TTC8
SE_02_106300137 chr14:88892972-88913605 Sample_02_1063 Brain CLB-GA-control 137 10 573 61 2 31 0 TTC8
SE_02_111300791 chr14:88895651-88906397 Sample_02_1113 Bone U2OS 791 3 277 27 0 30 0 TTC8
SE_02_029900394 chr14:88897756-88907318 Sample_02_0299 Neuroblastoma CLB-MA 394 2 259 23 1 28 0 TTC8
SE_02_025100321 chr14:88898998-88910882 Sample_02_0251 Autonomic ganglia SH-SY5Y-MYCN-OFF 321 2 318 33 2 28 0 TTC8
SE_02_034000352 chr14:88899088-88919926 Sample_02_0340 Brain BE2C_2 352 2 591 67 2 44 0 TTC8
SE_02_007500182 chr14:88899410-88907136 Sample_02_0075 Autonomic ganglia kelly_DMSO_3h 182 1 201 15 1 27 0 TTC8
SE_02_111500979 chr14:88900071-88906134 Sample_02_1115 Liver HepG2 979 2 145 11 0 27 0 TTC8
SE_02_124600061 chr14:88920860-89015406 Sample_02_1246 Brain LAN5_ATRA 61 35 2985 142 33 198 37 TTC8
SE_02_124500046 chr14:88927867-89014301 Sample_02_1245 Brain LAN5_Ethanol 46 35 2722 120 31 184 37 TTC8
SE_02_025200068 chr14:88932740-89015593 Sample_02_0252 Neuroblastoma IMR5-75-shMYCN-MYCN_high 68 15 2596 113 31 169 37 TTC8
SE_02_149900139 chr14:88939079-89001680 Sample_02_1499 Brain BE_2_-C 139 14 2011 89 30 149 37 TTC8
SE_02_042100108 chr14:88939318-89013239 Sample_02_0421 Brain BE2C_3 108 12 2363 105 30 157 37 TTC8
SE_02_110600168 chr14:88945257-89041561 Sample_02_1106 Brain NGP 168 40 3014 115 30 237 37 TTC8
SE_02_031300016 chr14:88946882-89042622 Sample_02_0313 Neuroblastoma SK-N-DZ 16 10 2991 116 30 238 37 TTC8
SE_02_030400063 chr14:88946953-89015169 Sample_02_0304 Neuroblastoma N206 63 10 2180 102 30 169 37 TTC8
SE_02_150000015 chr14:88947840-89014957 Sample_02_1500 Brain KELLY_untreat 15 29 2149 102 29 169 37 TTC8
SE_02_054000139 chr14:88952891-89014746 Sample_02_0540 Brain SK-N-BE_2_-C_PI3K_engineered 139 12 1979 86 24 161 37 TTC8
SE_02_030000134 chr14:88954629-89013293 Sample_02_0300 Neuroblastoma CLB-PE 134 9 1873 80 22 141 37 TTC8
SE_02_047100086 chr14:88961836-89015029 Sample_02_0471 Brain Kelly DMSO 86 34 1696 69 13 120 37 TTC8
SE_02_054200097 chr14:88962055-89042834 Sample_02_0542 Brain Kelly_ResJQ1 97 27 2503 83 13 186 37 TTC8
SE_02_054400149 chr14:88962151-89012876 Sample_02_0544 Brain Kelly_ResVeh 149 15 1619 65 13 103 37 TTC8
SE_02_054100051 chr14:88968859-89013403 Sample_02_0541 Brain Kelly_NaiveJQ1 51 13 1396 43 4 93 37 TTC8
SE_02_007500031 chr14:88971198-89002075 Sample_02_0075 Autonomic ganglia kelly_DMSO_3h 31 7 977 25 2 84 37 TTC8
SE_02_017300736 chr14:88971569-89009367 Sample_02_0173 Lung IMR-90_senescent 736 8 1200 32 2 84 37 TTC8
SE_02_025300093 chr14:88973816-89026598 Sample_02_0253 Brain BE2C_DMSO 93 7 1613 48 2 112 37 TTC8
SE_02_031800188 chr14:88974543-89002255 Sample_02_0318 Neuroblastoma NB69 188 3 851 22 2 84 37 TTC8
SE_02_029600165 chr14:88974622-89026499 Sample_02_0296 Neuroblastoma CLB-BER-Lud 165 6 1571 46 2 112 37 TTC8
SE_02_110500350 chr14:88974652-89042506 Sample_02_1105 Brain NBL-S 350 22 2048 54 2 173 37 TTC8
SE_02_025100181 chr14:88974732-89001789 Sample_02_0251 Autonomic ganglia SH-SY5Y-MYCN-OFF 181 3 838 22 2 84 37 TTC8
SE_02_031500085 chr14:88974798-89012974 Sample_02_0315 Neuroblastoma TR14 85 4 1180 37 2 90 37 TTC8
SE_02_053500015 chr14:88974824-89000054 Sample_02_0535 Brain SK-N-BE_2_-C_naive_vehicle 15 25 784 21 2 72 37 TTC8
SE_02_031900102 chr14:88974846-89015241 Sample_02_0319 Neuroblastoma NB-EBc1 102 7 1247 41 2 104 37 TTC8
SE_02_030300047 chr14:88974850-89042498 Sample_02_0303 Neuroblastoma LAN1 47 12 2046 54 2 173 37 TTC8
SE_02_030900020 chr14:88974861-89025756 Sample_02_0309 Neuroblastoma SJNB6 20 7 1551 46 2 112 37 TTC8
SE_02_033800076 chr14:88974966-89015243 Sample_02_0338 Neuroblastoma BE2 76 4 1245 41 2 104 37 TTC8
SE_02_106800025 chr14:88974979-89042273 Sample_02_1068 Brain NGP_ctrl 25 19 2036 53 2 172 37 TTC8
SE_02_054300098 chr14:88975094-89002769 Sample_02_0543 Brain Kelly_vehicle 98 9 852 21 2 84 37 TTC8
SE_01_011100131 chr14:88976009-89012827 Sample_01_0111 Brain SK-N-SH 131 8 1137 35 2 89 37 TTC8
SE_02_018300566 chr14:88978815-89014015 Sample_02_0183 Skin SKMEL2 566 7 1100 38 2 93 37 TTC8
SE_02_029800083 chr14:88979900-89009181 Sample_02_0298 Neuroblastoma CLB-GA 83 5 899 23 2 75 0 TTC8
SE_02_030600128 chr14:88981039-89003058 Sample_02_0306 Autonomic ganglia SH-SY5Y 128 2 663 17 1 65 0 TTC8
SE_02_029900078 chr14:88981134-89002326 Sample_02_0299 Neuroblastoma CLB-MA 78 2 636 16 1 65 0 TTC8
SE_02_106400093 chr14:88981641-89001805 Sample_02_1064 Brain CLB-GA-Dinaciclib_8h 93 6 610 15 1 65 0 TTC8
SE_02_152100600 chr14:88981648-89001974 Sample_02_1521 Skin A375 DMSO 600 8 613 15 1 65 0 TTC8
SE_02_040500216 chr14:88981963-89014470 Sample_02_0405 Mammary gland ZR-75-30_KO 216 8 988 34 1 84 0 TTC8
SE_02_030800279 chr14:88982038-89001524 Sample_02_0308 Neuroblastoma SJNB1 279 3 593 15 1 65 0 TTC8
SE_02_031000298 chr14:88982311-89002326 Sample_02_0310 Neuroblastoma SJNB8 298 2 601 15 1 65 0 TTC8
SE_02_106300083 chr14:88982363-89001787 Sample_02_1063 Brain CLB-GA-control 83 6 589 15 1 64 0 TTC8
SE_02_034000295 chr14:88982442-89001711 Sample_02_0340 Brain BE2C_2 295 2 585 15 1 64 0 TTC8
SE_02_042300640 chr14:88982457-89001531 Sample_02_0423 Skin A375 640 8 579 15 1 64 0 TTC8
SE_02_040600236 chr14:88982696-89001797 Sample_02_0406 Mammary gland ZR-75-30_parental 236 7 577 15 1 62 0 TTC8
SE_02_007600191 chr14:88982709-89001570 Sample_02_0076 Autonomic ganglia SH-SY5Y_DMSO_3h 191 2 571 15 1 62 0 TTC8
SE_02_093600179 chr14:88982748-89008455 Sample_02_0936 Retinal Pigmented Epithelial RPE188_TnT 179 7 779 20 1 62 0 TTC8
SE_02_111300618 chr14:88982847-89001457 Sample_02_1113 Bone U2OS 618 7 565 14 1 62 0 TTC8
SE_02_077101019 chr14:88982988-89001686 Sample_02_0771 Ovary OVCA429_shGRHL2 1019 16 569 14 1 62 0 TTC8
SE_02_111500773 chr14:88983090-89001587 Sample_02_1115 Liver HepG2 773 7 562 14 1 62 0 TTC8
SE_02_086900460 chr14:88983149-89005312 Sample_02_0869 Fibroblast VH10_NO_UV 460 17 666 17 1 62 0 TTC8
SE_02_031600670 chr14:88983187-89001803 Sample_02_0316 Neuroblastoma CHP212 670 2 562 14 1 62 0 TTC8
SE_02_006800724 chr14:88983323-89001704 Sample_02_0068 Skin A375_DMSO 724 7 553 14 1 62 0 TTC8
SE_02_093800441 chr14:88983349-89004985 Sample_02_0938 Retinal Pigmented Epithelial RPE190_TnT 441 6 640 17 1 62 0 TTC8
SE_02_057000689 chr14:88983387-89001426 Sample_02_0570 Brain LN229_10_mM_glucose 689 8 541 14 1 62 0 TTC8
SE_02_153400704 chr14:88983495-89008807 Sample_02_1534 Mammary gland MDA-MB-231_ER?WT_0min 704 5 762 20 1 62 0 TTC8
SE_02_053700008 chr14:88984506-89000719 Sample_02_0537 Brain SK-N-BE_2_-C_naive_JQ1 8 9 501 13 1 52 0 TTC8
SE_02_057201266 chr14:88984613-89001273 Sample_02_0572 Brain LN229_1_mM_glucose 1266 5 515 14 1 56 0 TTC8
SE_02_018800173 chr14:88986999-89012724 Sample_02_0188 Stomach MKN1 173 6 782 28 1 55 0 TTC8
SE_02_108400458 chr14:89040578-89047769 Sample_02_1084 Blood KBM7-derived near haploid cells 458 6 198 5 0 25 0 TTC8
Genomic distribution of SEs associated with TTC8
Genome Browser

The strength of the tissue affected by the gene

Expression of TTC8

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)