SEdb 2.0
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Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000063046
Gene: EIF4B Gene type: protein_coding
Strand: + External links:
Genomic region: chr12:53006282-53042215 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_040300032 chr12:52943099-53015695 Sample_02_0403 Mammary gland T-47D_untreat 32 8 1989 174 5 56 971 KRT18,EIF4B,KRT8,TENC1,LOC283335
SE_02_150100431 chr12:52964196-53008812 Sample_02_1501 Brain SHEP-21N_NOSPIKE 431 12 1225 116 1 55 171 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_081601251 chr12:52964624-53012576 Sample_02_0816 Ovary Clear cell ovarian cancer 1251 17 1329 124 1 56 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_020200024 chr12:52964651-53008588 Sample_02_0202 Stomach YCC7 24 12 1209 114 1 55 145 EIF4B,KRT18,TENC1,LOC283335
SE_02_115800077 chr12:52964973-52993817 Sample_02_1158 Mammary gland MCF7_siYTHDC1_E2 77 3 840 81 1 22 0 KRT18,EIF4B,KRT8,SPRYD3,LOC283335
SE_02_052500235 chr12:52965002-52993745 Sample_02_0525 Pancreas iPS derived pancreatic precursor cells_Lane1 235 10 837 81 1 22 0 KRT18,EIF4B,KRT8,KRT4
SE_02_125500210 chr12:52965110-52994328 Sample_02_1255 Bladder Bladder tumor Luminal2 210 11 856 81 1 22 0 KRT18,EIF4B,KRT8
SE_02_075700130 chr12:52965540-53014479 Sample_02_0757 Embryo ES-derived progenitors_FOXA2 -/- 130 9 1366 128 1 56 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_116200136 chr12:52965911-53024623 Sample_02_1162 Stomach YCC11 136 14 1611 153 2 84 460 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_01_001200210 chr12:52967054-53010680 Sample_01_0012 Lung A549_dexamethasone_1h 210 6 1211 115 1 55 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_020800019 chr12:52967102-52995862 Sample_02_0208 Stomach YCC3 19 9 837 85 1 22 0 KRT18,EIF4B
SE_03_001400268 chr12:52967144-53010590 Sample_03_0014 Lung A549_dexamethasone_2h 268 4 1205 115 1 55 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_109300500 chr12:52967299-52993725 Sample_02_1093 Mammary gland T47D_shCtrl_shRING1B_24hr 500 7 771 76 1 22 0 KRT18,EIF4B,KRT8
SE_03_001000412 chr12:52967320-53008935 Sample_03_0010 Lung A549_dexamethasone_1h 412 4 1146 110 1 55 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_152500220 chr12:52967345-53009356 Sample_02_1525 Stomach N87 DMSO 220 8 1161 111 1 55 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_123400153 chr12:52967435-53008638 Sample_02_1234 Mammary gland T47D_Full 153 7 1135 109 1 55 148 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_071800504 chr12:52967448-52994142 Sample_02_0718 Pancreas PATU8988S_GFP_DOX 504 6 778 76 1 22 0 KRT18,EIF4B,KRT8
SE_02_108600765 chr12:52967464-52993804 Sample_02_1086 Mammary gland T47D_shCtrl_0hr 765 8 769 76 1 22 0 KRT18,EIF4B,KRT8
SE_02_137100310 chr12:52967494-52994255 Sample_02_1371 Pancreas Patu899S-untreated 310 8 783 76 1 22 0 KRT18,EIF4B,KRT8
SE_02_050400612 chr12:52967510-53008908 Sample_02_0504 Esophagus KYSE510_1 612 13 1141 110 1 55 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_070300247 chr12:52967780-53012107 Sample_02_0703 Pancreas PATU8988S WT 247 14 1234 117 1 56 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_075400174 chr12:52967894-53013880 Sample_02_0754 Embryo ES-derived progenitors Pancreatic Progenitors 1 WT 174 10 1282 123 1 56 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_077800074 chr12:52968411-52993590 Sample_02_0778 Mammary gland MCF7_FASR 74 5 741 75 1 22 0 KRT18,EIF4B,KRT8,LOC283335,SPRYD3
SE_02_002100840 chr12:52968785-52994166 Sample_02_0021 Colon V429 840 4 745 75 1 22 0 KRT18,EIF4B
SE_02_152300187 chr12:52968821-53008300 Sample_02_1523 Lung A549 DMSO 187 6 1094 108 1 55 127 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_024200393 chr12:52968848-53009811 Sample_02_0242 Colon V481 393 7 1136 111 1 55 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_075300155 chr12:52969183-53012935 Sample_02_0753 Embryo ES-derived progenitors_FG type 155 12 1224 120 1 56 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_035200313 chr12:52969340-53015749 Sample_02_0352 Colon HCT116 313 9 1308 127 1 56 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_035400469 chr12:52969844-53009510 Sample_02_0354 Colon Colo205 469 8 1104 106 1 55 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_047800746 chr12:52969930-53009056 Sample_02_0478 Colon normal colon mucosa 746 16 1081 104 1 54 175 EIF4B,KRT18,TNS2,KRT8,LOC283335,MIR6757
SE_02_004400442 chr12:52974529-52993761 Sample_02_0044 Embryo endodermal CyT49_ES_D5 442 3 560 55 0 16 0 KRT18,EIF4B
SE_01_003800438 chr12:52981021-53008478 Sample_01_0038 Liver HepG2 438 5 727 64 0 35 137 EIF4B,KRT18,TENC1,LOC283335,KRT8,SOAT2
SE_02_104301913 chr12:52988205-53038804 Sample_02_1043 Peripheral blood Peripheral blood cells_CTCL1200 1913 12 1352 153 2 107 806 EIF4B,KRT18,TNS2,LOC283335,KRT8,SPRYD3,MIR6757
SE_02_019600337 chr12:52988264-52994204 Sample_02_0196 Stomach NCC59 337 2 179 16 0 0 0 KRT18,EIF4B
SE_02_071000538 chr12:52988530-53012047 Sample_02_0710 Pancreas hN34_organoid 538 7 624 55 0 33 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_071201012 chr12:52988792-53009283 Sample_02_0712 Pancreas BxPC3_sgNEG 1012 3 535 48 0 33 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_071700552 chr12:52988857-53009376 Sample_02_0717 Pancreas HPAFII_GFP_DOX 552 4 536 48 0 33 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_059000759 chr12:52988900-53008850 Sample_02_0590 Cervix HeLa Kyoto_Luci PWWP2A siRNA 759 6 517 46 0 33 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757,SPRYD3
SE_02_072100582 chr12:52988918-53009118 Sample_02_0721 Pancreas HPAFII_TP63dN_DOX 582 4 523 47 0 33 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_04_000600543 chr12:52991353-53008449 Sample_04_0006 Lung A549 GFP control 543 2 420 37 0 33 132 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_047600533 chr12:52991736-53012618 Sample_02_0476 iPSCs hiPSC derived hepatocyte-like cells 533 6 530 46 0 34 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_127300714 chr12:52991786-53015964 Sample_02_1273 Cervix HeLa 714 5 629 57 0 34 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757,SPRYD3
SE_02_026801173 chr12:52991787-53008601 Sample_02_0268 Kidney A-498 1173 5 408 36 0 33 146 EIF4B,KRT18,TENC1,LOC283335
SE_04_000200962 chr12:52992030-53015788 Sample_04_0002 Blood cold shocked K562 962 3 620 56 0 34 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757,TENC1,CSAD,SPRYD3,SOAT2,KRT79
SE_02_016400200 chr12:52992080-53011712 Sample_02_0164 Lung H2087_Parental 200 2 493 44 0 33 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_016500163 chr12:52992080-53011712 Sample_02_0165 Lung H2087_LCC2 163 2 493 44 0 33 175 EIF4B,KRT18,TENC1,LOC283335
SE_00_002400945 chr12:52992155-53007528 Sample_00_0024 Embryo mesendoderm 945 2 375 34 0 33 127 EIF4B,KRT18,TENC1,LOC283335
SE_02_040800372 chr12:52992183-53009535 Sample_02_0408 Kidney G401_Dox 372 3 428 39 0 33 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_012500627 chr12:52992291-53008950 Sample_02_0125 Embryo Embryonic-stem-cells_Primed 627 2 404 37 0 33 175 EIF4B,KRT18,TENC1,LOC283335
SE_02_158401470 chr12:52992359-53007864 Sample_02_1584 Brain U87 GBM_Mock 1470 2 380 35 0 33 127 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_101700462 chr12:52992392-53050820 Sample_02_1017 Embryo H9_Mesendoderm 24h_Hydroxyurea 462 11 1541 192 2 216 2183 EIF4B,TNS2,LOC283335,KRT18,IGFBP6,KRT8,SPRYD3,MIR6757
SE_02_122900724 chr12:52992522-53037082 Sample_02_1229 Haematopoietic and lymphoid tissue bone marrow K562_Control 724 20 1167 131 2 95 690 EIF4B,KRT18,TNS2,LOC283335,KRT8,SPRYD3,MIR6757,TENC1,CSAD,SOAT2,KRT79
SE_02_101600937 chr12:52992528-53014177 Sample_02_1016 Embryo H9_Mesendoderm_24h 937 3 563 52 0 34 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_02_148300832 chr12:52992917-53009447 Sample_02_1483 Bone RD-ES 832 4 409 35 0 33 175 EIF4B,KRT18,TNS2,LOC283335,KRT8,MIR6757
SE_01_003300443 chr12:53003695-53007706 Sample_01_0033 Embryo H9 443 1 113 7 0 33 127 EIF4B,TENC1,LOC283335
SE_02_032800567 chr12:53003703-53009729 Sample_02_0328 Embryo H9_naive 567 1 165 11 0 33 175 EIF4B,TENC1,LOC283335
SE_00_001800356 chr12:53003901-53008721 Sample_00_0018 Dermal fibroblasts iPS-18axian 356 2 132 8 0 33 154 EIF4B,TENC1,LOC283335
SE_02_003601428 chr12:53003906-53008877 Sample_02_0036 Embryo H7 1428 1 137 9 0 33 175 EIF4B,TENC1,LOC283335
SE_02_006400992 chr12:53003908-53008761 Sample_02_0064 Embryo DN-Early_G1 992 1 133 8 0 33 159 EIF4B,TENC1,LOC283335
SE_02_003900853 chr12:53003931-53009538 Sample_02_0039 Embryo AFG 853 1 160 11 0 33 175 EIF4B,TENC1,LOC283335
SE_02_003801137 chr12:53003939-53008831 Sample_02_0038 Embryo DE 1137 1 135 8 0 33 174 EIF4B,TENC1,LOC283335
SE_02_148200503 chr12:53004098-53014768 Sample_02_1482 Bone POE 503 4 305 26 0 34 175 EIF4B,TNS2,LOC283335,MIR6757
SE_02_088400912 chr12:53004220-53009489 Sample_02_0884 Colon LoVo 912 1 147 10 0 33 175 EIF4B,TNS2,LOC283335,MIR6757
SE_02_058400652 chr12:53004252-53031380 Sample_02_0584 Lung H1299 WT 652 6 737 83 2 77 557 EIF4B,TNS2,LOC283335,SPRYD3,MIR6757
Genomic distribution of SEs associated with EIF4B
Genome Browser

The strength of the tissue affected by the gene

Expression of EIF4B

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)