5.1 Why are showing no results available somewhere?
Reply: Because there is no corresponding function annotation or no significant annotation
results for this TF/gene.
5.2 Why the same TF disrupted by the same knockdown/knockout
technique appears in different datasets?
Reply: Because these datasets may be from different profiles, different platforms or different
biosamples. In KnockTF, there are two data sources. If data source is GEO, five conditions are
used to uniquely determine a dataset, including TF, knockdown/knockout technique, biosample
name, series (GSE) and platform (GPL); if data source is ENCODE, four conditions are used to
uniquely determine a dataset, including TF, knockdown/knockout technique, biosample name and
5.3 Which kinds of species are stored in the database?
Reply: The current version of KnockTF stores the most abundant human and mouse gene expression profile
datasets of TF knockdown/knockout. There may be a lot of TF knockdown/knockout data about other
species in other data sources. In the next version of KnockTF, we will manually curate more TF
knockdown/knockout data with more species and enrich the kinds of species information.
5.4 Why might web pages load slowly?
Reply: KnockTF has advanced storage technology and sufficient bandwidth to meet the needs of
most users for the speed of web page loading. However, it is not excluded that few users have
poor user experience due to network reasons.