T(co)F Enrichment

Genes

Example of upload file

Threshold

 


Function Introduction

Users can submit a gene list and set (FDR adjusted) P-value to perform T(co)F enrichment.
KnockTF will map these submitted genes to the T(co)F-differentially expressed gene network and perform Hypergeometric test between the submitted genes and all the differentially expressed genes regulated by each T(co)F.
The T(co)Fs under the threshold of (FDR adjusted) P-value users set are regarded as the most important T(co)Fs significantly regulating the submitted genes.