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T(co)F Overview
T(co)F: STAT1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: STAT domain factors
T(co)F Superclass: Immunoglobulin fold
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 3
# of Treat: 1
Data Source: GEO
Profile ID: GSE31912
Platform: GPL570
Pubmed ID: 22536322

STAT1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of STAT1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of STAT1

Upstream Pathway Annotation of STAT1
T(co)F Pathway Name Source Gene Number
STAT1
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Hs_Insulin_signalling_in_adipocytes_(diabetic_condition)_WP3635_86059
WikiPathways 6
STAT1
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Hs_Insulin_signalling_in_adipocytes_(normal_condition)_WP3634_86060
WikiPathways 6
STAT1
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IFN gamma signaling pathway(JAK1 JAK2 STAT1) ( IFN gamma signaling(JAK1 JAK2 STAT1) )
INOH 6
STAT1
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Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )
INOH 8
STAT1
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Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )
INOH 8
STAT1
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Hs_One_carbon_metabolism_and_related_pathways_WP3940_91096
WikiPathways 10
STAT1
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Interleukin-6 signaling
Reactome 11
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-9_Signaling_Pathway_WP22_79264
WikiPathways 11
STAT1
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IL-5 signaling pathway(JAK1 JAK2 STAT1 STAT5) ( IL-5 signaling(JAK1 JAK2 STAT1 STAT5) )
INOH 11
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_PDGF_Pathway_WP2526_82681
WikiPathways 12
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) )
INOH 12
STAT1
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Regulation of IFNG signaling
Reactome 14
STAT1
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Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )
INOH 14
STAT1
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JAK/STAT signaling pathway
PANTHER 15
STAT1
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Hs_Interleukin-11_Signaling_Pathway_WP2332_79525
WikiPathways 17
STAT1
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Signaling by cytosolic FGFR1 fusion mutants
Reactome 18
STAT1
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IFN alpha signaling pathway(JAK1 TYK2 STAT1) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) )
INOH 18
STAT1
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IFN alpha signaling pathway(JAK1 TYK2 STAT1 STAT3) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) )
INOH 19
STAT1
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IFN alpha signaling pathway((JAK1 TYK2 STAT1 STAT2) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) )
INOH 20
STAT1
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Hs_Cytokines_and_Inflammatory_Response_WP530_79331
WikiPathways 21
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Oxidative stress response
PANTHER 23
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Growth hormone receptor signaling
Reactome 24
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL9
NetPath 24
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
TSLP
NetPath 24
STAT1
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Regulation of IFNA signaling
Reactome 26
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-6_signaling_pathway_WP364_89832
WikiPathways 26
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL27-mediated signaling events
PID 26
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL-7
NetPath 28
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Downstream signal transduction
Reactome 29
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Interferon-gamma signaling pathway
PANTHER 29
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Integrated_Cancer_Pathway_WP1971_82939
WikiPathways 33
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-2_Signaling_Pathway_WP49_91243
WikiPathways 33
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
EPO signaling pathway
PID 33
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Interferon_type_I_signaling_pathways_WP585_85198
WikiPathways 35
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-5_Signaling_Pathway_WP127_78498
WikiPathways 35
STAT1
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Signaling by SCF-KIT
Reactome 37
STAT1
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Hs_Leptin_signaling_pathway_WP2034_89856
WikiPathways 37
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL23-mediated signaling events
PID 37
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
GMCSF-mediated signaling events
PID 38
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Signaling events mediated by TCPTP
PID 40
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-4_Signaling_Pathway_WP395_89828
WikiPathways 41
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Endochondral_Ossification_WP474_87977
WikiPathways 43
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IFN-gamma pathway
PID 43
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668
WikiPathways 44
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Kit_receptor_signaling_pathway_WP304_78799
WikiPathways 46
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
TNF receptor signaling pathway
PID 46
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL6-mediated signaling events
PID 48
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Prolactin_Signaling_Pathway_WP2037_90015
WikiPathways 52
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Signaling events mediated by Stem cell factor receptor (c-Kit)
PID 53
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL2-mediated signaling events
PID 54
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
FGF signaling pathway
PID 55
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL5
NetPath 59
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
SHP2 signaling
PID 60
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Endoderm_Differentiation_WP2853_88152
WikiPathways 62
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL12-mediated signaling events
PID 62
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Interferon alpha/beta signaling
Reactome 67
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Ras Pathway
PANTHER 69
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Pancreatic cancer
KEGG 70
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Leishmaniasis
KEGG 71
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
ISG15 antiviral mechanism
Reactome 73
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL4
NetPath 75
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803
WikiPathways 80
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL2
NetPath 81
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
TSH
NetPath 82
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
RANKL
NetPath 84
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL6
NetPath 85
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Glucocorticoid receptor regulatory network
PID 85
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Interleukin signaling pathway
PANTHER 86
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
CXCR4-mediated signaling events
PID 87
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Interferon gamma signaling
Reactome 88
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
JAK-STAT pathway and regulation pathway ( JAK-STAT pathway and regulation pathway Diagram )
INOH 97
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Leptin
NetPath 98
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Toll-like receptor signaling pathway
KEGG 100
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
KitReceptor
NetPath 104
STAT1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Prolactin
NetPath 105
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
ErbB1 downstream signaling
PID 105
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_EGF-EGFR_Signaling_Pathway_WP437_79266
WikiPathways 107
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
EGF receptor signaling pathway
PANTHER 109
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGF signaling pathway
PANTHER 113
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941
WikiPathways 122
STAT1
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGFR-beta signaling pathway
PID 125
STAT1
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Toxoplasmosis
KEGG 131
STAT1
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Hepatitis C
KEGG 134
STAT1
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Angiogenesis
PANTHER 141
STAT1
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Jak-STAT signaling pathway
KEGG 149
STAT1
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Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000
WikiPathways 153
STAT1
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BCR
NetPath 161
STAT1
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Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram )
INOH 178
STAT1
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Chemokine signaling pathway
KEGG 187
STAT1
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TCR
NetPath 261
STAT1
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TNFalpha
NetPath 274
STAT1
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Pathways in cancer
KEGG 321
STAT1
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EGFR1
NetPath 475
Target Gene Expression Analysis
Expression Atlas of STAT1