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T(co)F Overview
T(co)F: SRF
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: MADS box factors
T(co)F Superclass: alpha-Helices exposed by beta-structures
Biosample Name: LNCaP
Tissue Type: Prostate
Biosample Type: Cell line
# of Control: 6
# of Treat: 6
Data Source: GEO
Profile ID: GSE22606
Platform: GPL570
Pubmed ID: 21324924

SRF- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SRF
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SRF

Upstream Pathway Annotation of SRF
T(co)F Pathway Name Source Gene Number
SRF
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Hs_Serotonin_Receptor_2_and_ELK-SRF-GATA4_signaling_WP732_80010
WikiPathways 13
SRF
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Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438
WikiPathways 15
SRF
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p38 signaling mediated by MAPKAP kinases
PID 21
SRF
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PDGFR-alpha signaling pathway
PID 22
SRF
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p38 MAPK pathway
PANTHER 31
SRF
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Trk receptor signaling mediated by the MAPK pathway
PID 34
SRF
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RhoA signaling pathway
PID 46
SRF
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Hs_Mesodermal_Commitment_Pathway_WP2857_87780
WikiPathways 47
SRF
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Signaling events mediated by HDAC Class II
PID 58
SRF
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Coregulation of Androgen receptor activity
PID 61
SRF
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Ras Pathway
PANTHER 69
SRF
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Interleukin signaling pathway
PANTHER 86
SRF
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ErbB1 downstream signaling
PID 105
SRF
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PDGF signaling pathway
PANTHER 113
SRF
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RHO GTPases Activate Formins
Reactome 114
SRF
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PDGFR-beta signaling pathway
PID 125
SRF
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Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000
WikiPathways 153
SRF
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MAPK signaling pathway
KEGG 264
Target Gene Expression Analysis
Expression Atlas of SRF