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T(co)F Overview
T(co)F: Klf4
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: Primary neonatal keratinocytes
Tissue Type: Skin
Biosample Type: Primary cell
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE32685
Platform: GPL570
Pubmed ID: 22364861

Klf4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Klf4
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Klf4

Upstream Pathway Annotation of Klf4
T(co)F Pathway Name Source Gene Number
Klf4
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Hs_Role_of_Osx_and_miRNAs_in_tooth_development_WP3971_91525
WikiPathways 9
Klf4
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Synthesis, secretion, and deacylation of Ghrelin
Reactome 17
Klf4
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Transcriptional regulation of pluripotent stem cells
Reactome 28
Klf4
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Hs_White_fat_cell_differentiation_WP3946_90940
WikiPathways 30
Klf4
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Hs_Mesodermal_Commitment_Pathway_WP2857_87780
WikiPathways 47
Klf4
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Transcriptional regulation of white adipocyte differentiation
Reactome 79
Klf4
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Regulation of nuclear beta catenin signaling and target gene transcription
PID 80
Target Gene Expression Analysis
Expression Atlas of Klf4