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T(co)F Overview
T(co)F: ETS1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: WI38
Tissue Type: Fibroblasts
Biosample Type: Cell line
# of Control: 12
# of Treat: 8
Data Source: GEO
Profile ID: GSE144397
Platform: GPL17586
Pubmed ID: 32514071

ETS1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of ETS1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of ETS1

Upstream Pathway Annotation of ETS1
T(co)F Pathway Name Source Gene Number
ETS1
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MAPK signaling pathway - fly
KEGG 16
ETS1
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ERK cascade ( FGF8 signaling (Mouse) )
INOH 17
ETS1
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ERK cascade ( FGF8 signaling (Xenopus) )
INOH 17
ETS1
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FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) )
INOH 18
ETS1
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FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) )
INOH 20
ETS1
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Dorso-ventral axis formation
KEGG 25
ETS1
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Oncogene Induced Senescence
Reactome 30
ETS1
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HIF-2-alpha transcription factor network
PID 34
ETS1
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Hs_Neural_Crest_Differentiation_WP2064_79263
WikiPathways 40
ETS1
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Angiopoietin receptor Tie2-mediated signaling
PID 50
ETS1
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Hs_Apoptosis-related_network_due_to_altered_Notch3_in_ovarian_cancer_WP2864_79278
WikiPathways 51
ETS1
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VEGF signaling pathway
PANTHER 54
ETS1
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Signaling events mediated by focal adhesion kinase
PID 63
ETS1
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IL4-mediated signaling events
PID 66
ETS1
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Hs_TGF-beta_Signaling_Pathway_WP366_90028
WikiPathways 67
ETS1
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HIF-1-alpha transcription factor network
PID 67
ETS1
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Ras Pathway
PANTHER 69
ETS1
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BCR signaling pathway
PID 70
ETS1
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Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900
WikiPathways 71
ETS1
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AP-1 transcription factor network
PID 71
ETS1
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IL4
NetPath 75
ETS1
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Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
PID 80
ETS1
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IL2
NetPath 81
ETS1
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C-MYB transcription factor network
PID 87
ETS1
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PDGF signaling pathway
PANTHER 113
ETS1
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Angiogenesis
PANTHER 141
ETS1
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Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000
WikiPathways 153
ETS1
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TGF_beta_Receptor
NetPath 220
Target Gene Expression Analysis
Expression Atlas of ETS1