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T(co)F Overview
T(co)F: EP300
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: LNCaP
Tissue Type: Prostate
Biosample Type: Cell line
# of Control: 6
# of Treat: 6
Data Source: GEO
Profile ID: GSE66722
Platform: GPL19874
Pubmed ID: -

EP300- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of EP300
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of EP300

Upstream Pathway Annotation of EP300
T(co)F Pathway Name Source Gene Number
EP300
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LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
Reactome 5
EP300
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BMP signaling in Drosophila ( BMP signaling in Drosophila )
INOH 7
EP300
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BMP signaling in Drosophila (dorsal midline) ( BMP signaling in Drosophila )
INOH 7
EP300
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BMP signaling in Drosophila (dorsolateral) ( BMP signaling in Drosophila )
INOH 7
EP300
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C. elegans Notch signaling pathway ( Notch signaling pathway Diagram )
INOH 8
EP300
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Regulation of gene expression by Hypoxia-inducible Factor
Reactome 10
EP300
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LIF signaling pathway ( LIF signaling(JAK1 JAK2 STAT3) )
INOH 10
EP300
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NOTCH2 intracellular domain regulates transcription
Reactome 12
EP300
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BMP2 signaling pathway(through Smad) ( TGF-beta_BMP Diagram(MolecularVariation) )
INOH 13
EP300
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TRAF3-dependent IRF activation pathway
Reactome 14
EP300
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Mammalian Notch signaling pathway ( Notch signaling pathway Diagram )
INOH 15
EP300
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Polo-like kinase mediated events
Reactome 16
EP300
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Hs_Signaling_Pathways_in_Glioblastoma_WP2261_89520
WikiPathways 16
EP300
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Hs_Notch_Signaling_Pathway_WP61_78592
WikiPathways 16
EP300
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TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome 18
EP300
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Regulation of TP53 Activity through Methylation
Reactome 19
EP300
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Canonical Notch signaling pathway ( Notch signaling pathway Diagram )
INOH 19
EP300
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Signaling with Wnt (Xenopus) ( Xenopus axis formation Wnt signaling pathway Diagram )
INOH 19
EP300
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CD209 (DC-SIGN) signaling
Reactome 21
EP300
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Regulation of TP53 Activity through Acetylation
Reactome 23
EP300
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RORA activates gene expression
Reactome 27
EP300
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Attenuation phase
Reactome 28
EP300
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Pre-NOTCH Transcription and Translation
Reactome 29
EP300
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Retinoic acid receptors-mediated signaling
PID 30
EP300
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TRAF6 mediated IRF7 activation
Reactome 33
EP300
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HIF-2-alpha transcription factor network
PID 34
EP300
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BMP signaling pathway ( TGF-beta_BMP Diagram(MolecularVariation) )
INOH 34
EP300
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Validated transcriptional targets of AP1 family members Fra1 and Fra2
PID 37
EP300
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p53 pathway
PANTHER 39
EP300
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Signaling events mediated by HDAC Class III
PID 41
EP300
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BMAL1:CLOCK,NPAS2 activates circadian gene expression
Reactome 42
EP300
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Transcription regulation by bZIP transcription factor
PANTHER 42
EP300
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FOXM1 transcription factor network
PID 43
EP300
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IFN-gamma pathway
PID 43
EP300
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Notch signaling pathway
KEGG 44
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Reactome 44
EP300
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FOXA1 transcription factor network
PID 45
EP300
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Hs_Kit_receptor_signaling_pathway_WP304_78799
WikiPathways 46
EP300
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NOTCH1 Intracellular Domain Regulates Transcription
Reactome 47
EP300
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Signaling with Wnt (Canonical) ( C. elegans endoderm induction Wnt signaling pathway Diagram )
INOH 47
EP300
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Signaling with Wnt (Canonical) ( Canonical Wnt signaling pathway Diagram )
INOH 47
EP300
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Signaling with Wnt (Canonical) ( Drosophila Wingless/Wnt signaling pathway Diagram )
INOH 47
EP300
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Signaling with Wnt (Canonical) ( Mammalian Wnt signaling pathway Diagram )
INOH 47
EP300
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Signaling with Wnt (Canonical) ( Xenopus axis formation Wnt signaling pathway Diagram )
INOH 47
EP300
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Signaling with Wnt (Mammal) ( Mammalian Wnt signaling pathway Diagram )
INOH 47
EP300
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Notch-mediated HES/HEY network
PID 48
EP300
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Circadian Clock
Reactome 49
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
FoxO family signaling
PID 50
EP300
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TGF-beta_super_family_signaling_pathway(canonical) ( TGF-beta_BMP Diagram(MolecularVariation) )
INOH 51
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Formation of TC-NER Pre-Incision Complex
Reactome 53
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Regulation of Androgen receptor activity
PID 54
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Role of Calcineurin-dependent NFAT signaling in lymphocytes
PID 54
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Validated transcriptional targets of TAp63 isoforms
PID 54
EP300
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Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Reactome 57
EP300
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Constitutive Signaling by NOTCH1 PEST Domain Mutants
Reactome 57
EP300
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Notch signaling pathway
PID 58
EP300
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ATF-2 transcription factor network
PID 59
EP300
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p53 pathway
PID 59
EP300
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Gap-filling DNA repair synthesis and ligation in TC-NER
Reactome 62
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Dual incision in TC-NER
Reactome 63
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Validated targets of C-MYC transcriptional repression
PID 63
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Renal cell carcinoma
KEGG 65
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Validated nuclear estrogen receptor alpha network
PID 65
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Long-term potentiation
KEGG 67
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
HIF-1-alpha transcription factor network
PID 67
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Regulation of retinoblastoma protein
PID 67
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Adherens junction
KEGG 70
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
AP-1 transcription factor network
PID 71
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL4
NetPath 75
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Notch
NetPath 76
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
E2F transcription factor network
PID 77
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Transcriptional regulation of white adipocyte differentiation
Reactome 79
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
p73 transcription factor network
PID 80
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Regulation of nuclear beta catenin signaling and target gene transcription
PID 80
EP300
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Validated targets of C-MYC transcriptional activation
PID 80
EP300
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TGF-beta signaling pathway
KEGG 82
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Regulation of nuclear SMAD2/3 signaling
PID 82
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Prostate cancer
KEGG 85
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL6
NetPath 85
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Glucocorticoid receptor regulatory network
PID 85
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
C-MYB transcription factor network
PID 87
EP300
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Formation of the beta-catenin:TCF transactivating complex
Reactome 88
EP300
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TGF-beta signaling pathway
PANTHER 88
EP300
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B-WICH complex positively regulates rRNA expression
Reactome 89
EP300
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Signaling events mediated by HDAC Class I
PID 89
EP300
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Leptin
NetPath 98
EP300
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Melanogenesis
KEGG 100
EP300
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KitReceptor
NetPath 104
EP300
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Prolactin
NetPath 105
EP300
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Factors involved in megakaryocyte development and platelet production
Reactome 111
EP300
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PPARA activates gene expression
Reactome 113
EP300
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Huntington disease
PANTHER 113
EP300
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Activation of anterior HOX genes in hindbrain development during early embryogenesis
Reactome 120
EP300
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Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941
WikiPathways 122
EP300
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Cell cycle
KEGG 124
EP300
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Wnt signaling pathway
KEGG 135
EP300
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Direct p53 effectors
PID 141
EP300
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HATs acetylate histones
Reactome 142
EP300
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Jak-STAT signaling pathway
KEGG 149
EP300
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AndrogenReceptor
NetPath 167
EP300
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Huntington's disease
KEGG 182
EP300
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TGF_beta_Receptor
NetPath 220
EP300
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Wnt signaling pathway
PANTHER 250
EP300
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TNFalpha
NetPath 274
EP300
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Pathways in cancer
KEGG 321
Target Gene Expression Analysis
Expression Atlas of EP300