| T(co)F: | BRCA1 |
| Species: | Homo sapiens |
| Knock-Method: | siRNA |
| T(co)F Class: | Others |
| T(co)F Superclass: | TcoF-DB_TF |
| Biosample Name: | MCF7 |
| Tissue Type: | Mammary_gland |
| Biosample Type: | Cell line |
| # of Control: | 3 | # of Treat: | 1 |
| Data Source: | GEO |
| Profile ID: | GSE31912 |
| Platform: | GPL570 |
| Pubmed ID: | 22536322 |
#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines
| Target Gene | T(co)F | Mean
Expr. of
Control
|
Mean
Expr. of
Treat
|
Fold Change | Log2FC | Rank | P-value | Corrected _P |
Promoter _T(co)F |
SE_T(co)F | TE_T(co)F |
|---|
| T(co)F | Pathway Name | Source | Gene Number |
|---|---|---|---|
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_Signaling_Pathways_in_Glioblastoma_WP2261_89520 |
WikiPathways | 16 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Homologous DNA Pairing and Strand Exchange |
Reactome | 25 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) |
Reactome | 26 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 |
WikiPathways | 27 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_DNA_Damage_Response_WP707_82937 |
WikiPathways | 28 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694 |
WikiPathways | 28 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 BARD1 signaling events |
PID | 29 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_ATM_Signaling_Pathway_WP2516_90247 |
WikiPathways | 32 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Resolution of D-loop Structures through Holliday Junction Intermediates |
Reactome | 33 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_Integrated_Cancer_Pathway_WP1971_82939 |
WikiPathways | 33 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Aurora A signaling |
PID | 33 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 ATM pathway |
PID | 34 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_Hepatitis_C_and_Hepatocellular_Carcinoma_WP3646_88640 |
WikiPathways | 36 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 HDR through Single Strand Annealing (SSA) |
Reactome | 37 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Presynaptic phase of homologous DNA pairing and strand exchange |
Reactome | 39 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 FOXA1 transcription factor network |
PID | 45 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 HDR through Homologous Recombination (HRR) |
Reactome | 46 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Fanconi anemia pathway |
PID | 48 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_DNA_IR-Double_Strand_Breaks_(DSBs)_and_cellular_response_via_ATM_WP3959_91367 |
WikiPathways | 50 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 ATF-2 transcription factor network |
PID | 59 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 TP53 Regulates Transcription of DNA Repair Genes |
Reactome | 61 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Coregulation of Androgen receptor activity |
PID | 61 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Validated targets of C-MYC transcriptional repression |
PID | 63 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Validated nuclear estrogen receptor alpha network |
PID | 65 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Nonhomologous End-Joining (NHEJ) |
Reactome | 69 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
Reactome | 75 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Meiotic synapsis |
Reactome | 76 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 SUMOylation of DNA damage response and repair proteins |
Reactome | 76 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 E2F transcription factor network |
PID | 77 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 G2/M DNA damage checkpoint |
Reactome | 84 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Meiotic recombination |
Reactome | 85 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Regulation of TP53 Activity through Phosphorylation |
Reactome | 89 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Processing of DNA double-strand break ends |
Reactome | 98 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 |
WikiPathways | 122 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 AndrogenReceptor |
NetPath | 167 |
| BRCA1 | Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779 Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779 TGF_beta_Receptor |
NetPath | 220 |