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T(co)F Overview
T(co)F: AR
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Nuclear receptors with C4 zinc fingers
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: LNCaP
Tissue Type: Prostate
Biosample Type: Cell line
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE11428
Platform: GPL570
Pubmed ID: 19632176

AR- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of AR
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of AR

Upstream Pathway Annotation of AR
T(co)F Pathway Name Source Gene Number
AR
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Hs_Androgen_receptor_signaling_pathway_WP138_79958
WikiPathways 27
AR
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Hs_DNA_Damage_Response_WP707_82937
WikiPathways 28
AR
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Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694
WikiPathways 28
AR
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Nongenotropic Androgen signaling
PID 31
AR
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Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078
WikiPathways 33
AR
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FOXA1 transcription factor network
PID 45
AR
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Notch-mediated HES/HEY network
PID 48
AR
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Nuclear Receptor transcription pathway
Reactome 51
AR
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Regulation of Androgen receptor activity
PID 54
AR
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Coregulation of Androgen receptor activity
PID 61
AR
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Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Reactome 65
AR
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Alpha6Beta4Integrin
NetPath 74
AR
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Regulation of nuclear beta catenin signaling and target gene transcription
PID 80
AR
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Regulation of nuclear SMAD2/3 signaling
PID 82
AR
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Prostate cancer
KEGG 85
AR
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IL6
NetPath 85
AR
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Oocyte meiosis
KEGG 110
AR
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Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941
WikiPathways 122
AR
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AndrogenReceptor
NetPath 167
AR
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TGF_beta_Receptor
NetPath 220
AR
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Pathways in cancer
KEGG 321
Target Gene Expression Analysis
Expression Atlas of AR