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T(co)F Overview
T(co)F: MAX
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Basic helix-loop-helix factors (bHLH)
T(co)F Superclass: Basic domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR675SDG
Platform: -
Pubmed ID: 22955616

MAX- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of MAX
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of MAX

Upstream Pathway Annotation of MAX
T(co)F Pathway Name Source Gene Number
MAX
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Cyclin E associated events during G1/S transition
Reactome 14
MAX
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Cyclin A:Cdk2-associated events at S phase entry
Reactome 15
MAX
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Oxidative stress response
PANTHER 23
MAX
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C-MYC pathway
PID 25
MAX
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Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271
WikiPathways 27
MAX
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Validated targets of C-MYC transcriptional repression
PID 63
MAX
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Regulation of Telomerase
PID 70
MAX
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Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900
WikiPathways 71
MAX
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Validated targets of C-MYC transcriptional activation
PID 80
MAX
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Regulation of nuclear SMAD2/3 signaling
PID 82
MAX
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Small cell lung cancer
KEGG 83
MAX
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Signaling events mediated by HDAC Class I
PID 89
MAX
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Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941
WikiPathways 122
MAX
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MAPK signaling pathway
KEGG 264
MAX
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Pathways in cancer
KEGG 321
Target Gene Expression Analysis
Expression Atlas of MAX