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T(co)F Overview
T(co)F: KAT2B
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR576FFB
Platform: -
Pubmed ID: 22955616

KAT2B- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of KAT2B
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of KAT2B

Upstream Pathway Annotation of KAT2B
T(co)F Pathway Name Source Gene Number
KAT2B
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Physiological factors
Reactome 12
KAT2B
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NICD traffics to nucleus
Reactome 13
KAT2B
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Notch-HLH transcription pathway
Reactome 13
KAT2B
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Pre-NOTCH Transcription and Translation
Reactome 29
KAT2B
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YAP1- and WWTR1 (TAZ)-stimulated gene expression
Reactome 29
KAT2B
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Retinoic acid receptors-mediated signaling
PID 30
KAT2B
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p53 pathway
PANTHER 39
KAT2B
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Signaling events mediated by HDAC Class III
PID 41
KAT2B
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Notch signaling pathway
KEGG 44
KAT2B
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NOTCH1 Intracellular Domain Regulates Transcription
Reactome 47
KAT2B
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RNA Polymerase I Transcription Initiation
Reactome 47
KAT2B
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FoxO family signaling
PID 50
KAT2B
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Regulation of Androgen receptor activity
PID 54
KAT2B
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Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Reactome 57
KAT2B
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Constitutive Signaling by NOTCH1 PEST Domain Mutants
Reactome 57
KAT2B
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p53 pathway
PID 59
KAT2B
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Notch
NetPath 76
KAT2B
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E2F transcription factor network
PID 77
KAT2B
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Regulation of nuclear SMAD2/3 signaling
PID 82
KAT2B
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B-WICH complex positively regulates rRNA expression
Reactome 89
KAT2B
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Signaling events mediated by HDAC Class I
PID 89
KAT2B
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HATs acetylate histones
Reactome 142
KAT2B
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AndrogenReceptor
NetPath 167
KAT2B
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TGF_beta_Receptor
NetPath 220
Target Gene Expression Analysis
Expression Atlas of KAT2B