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T(co)F Overview
T(co)F: AGO2
Species: Homo sapiens
Knock-Method: shRNA
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR495YSS
Platform: -
Pubmed ID: 22955616

AGO2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of AGO2
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of AGO2

Upstream Pathway Annotation of AGO2
T(co)F Pathway Name Source Gene Number
AGO2
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Post-transcriptional silencing by small RNAs
Reactome 7
AGO2
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Small interfering RNA (siRNA) biogenesis
Reactome 9
AGO2
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MicroRNA (miRNA) biogenesis
Reactome 23
AGO2
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Pre-NOTCH Transcription and Translation
Reactome 29
AGO2
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Ca2+ pathway
Reactome 62
AGO2
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PIP3 activates AKT signaling
Reactome 81
AGO2
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TP53 Regulates Metabolic Genes
Reactome 85
AGO2
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MAPK6/MAPK4 signaling
Reactome 90
AGO2
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Transcriptional regulation by small RNAs
Reactome 104
Target Gene Expression Analysis
Expression Atlas of AGO2