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T(co)F Overview
T(co)F: NR4A1
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Nuclear receptors with C4 zinc fingers
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR357LVC
Platform: -
Pubmed ID: 22955616

NR4A1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NR4A1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NR4A1

Upstream Pathway Annotation of NR4A1
T(co)F Pathway Name Source Gene Number
NR4A1
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AKT phosphorylates targets in the nucleus
Reactome 9
NR4A1
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Constitutive Signaling by AKT1 E17K in Cancer
Reactome 25
NR4A1
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RXR and RAR heterodimerization with other nuclear receptor
PID 26
NR4A1
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Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017
WikiPathways 41
NR4A1
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Nuclear Receptor transcription pathway
Reactome 51
NR4A1
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
PID 54
NR4A1
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Hs_MAPK_Signaling_Pathway_WP382_79951
WikiPathways 58
NR4A1
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Glucocorticoid receptor regulatory network
PID 85
NR4A1
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TCR
NetPath 261
NR4A1
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MAPK signaling pathway
KEGG 264
Target Gene Expression Analysis
Expression Atlas of NR4A1