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T(co)F Overview
T(co)F: TFDP1
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Fork head / winged helix factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR552HTC
Platform: -
Pubmed ID: 22955616

TFDP1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of TFDP1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of TFDP1

Upstream Pathway Annotation of TFDP1
T(co)F Pathway Name Source Gene Number
TFDP1
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Activation of PUMA and translocation to mitochondria
Reactome 8
TFDP1
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Inhibition of replication initiation of damaged DNA by RB1/E2F1
Reactome 12
TFDP1
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E2F mediated regulation of DNA replication
Reactome 17
TFDP1
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G1/S-Specific Transcription
Reactome 17
TFDP1
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TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome 18
TFDP1
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G0 and Early G1
Reactome 25
TFDP1
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Pre-NOTCH Transcription and Translation
Reactome 29
TFDP1
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Oncogene Induced Senescence
Reactome 30
TFDP1
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SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome 32
TFDP1
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Cyclin D associated events in G1
Reactome 38
TFDP1
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Hs_Tryptophan_metabolism_WP465_85055
WikiPathways 45
TFDP1
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Regulation of retinoblastoma protein
PID 67
TFDP1
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E2F transcription factor network
PID 77
TFDP1
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TGF-beta signaling pathway
KEGG 82
TFDP1
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Regulation of nuclear SMAD2/3 signaling
PID 82
TFDP1
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Oxidative Stress Induced Senescence
Reactome 120
TFDP1
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Cell cycle
KEGG 124
TFDP1
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Direct p53 effectors
PID 141
TFDP1
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TGF_beta_Receptor
NetPath 220
Target Gene Expression Analysis
Expression Atlas of TFDP1