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T(co)F Overview
T(co)F: NRF1
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Basic leucine zipper factors (bZIP)
T(co)F Superclass: Basic domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 3
Data Source: ENCODE
Profile ID: ENCSR299HUJ
Platform: -
Pubmed ID: 22955616

NRF1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NRF1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NRF1

Upstream Pathway Annotation of NRF1
T(co)F Pathway Name Source Gene Number
NRF1
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Hs_Mitochondrial_Gene_Expression_WP391_71373
WikiPathways 11
NRF1
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Hs_Energy_Metabolism_WP1541_91584
WikiPathways 13
NRF1
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Transcriptional activation of mitochondrial biogenesis
Reactome 43
NRF1
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PPARA activates gene expression
Reactome 113
NRF1
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Huntington's disease
KEGG 182
Target Gene Expression Analysis
Expression Atlas of NRF1