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T(co)F Overview
T(co)F: CTBP1
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR171RTN
Platform: -
Pubmed ID: 22955616

CTBP1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of CTBP1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of CTBP1

Upstream Pathway Annotation of CTBP1
T(co)F Pathway Name Source Gene Number
CTBP1
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Repression of WNT target genes
Reactome 14
CTBP1
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Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271
WikiPathways 27
CTBP1
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ATM pathway
PID 34
CTBP1
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Deactivation of the beta-catenin transactivating complex
Reactome 42
CTBP1
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Notch signaling pathway
KEGG 44
CTBP1
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Presenilin action in Notch and Wnt signaling
PID 46
CTBP1
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Notch-mediated HES/HEY network
PID 48
CTBP1
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Hs_Ectoderm_Differentiation_WP2858_89329
WikiPathways 56
CTBP1
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Notch signaling pathway
PID 58
CTBP1
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Regulation of retinoblastoma protein
PID 67
CTBP1
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Chronic myeloid leukemia
KEGG 69
CTBP1
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Regulation of nuclear beta catenin signaling and target gene transcription
PID 80
CTBP1
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Regulation of nuclear SMAD2/3 signaling
PID 82
CTBP1
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Wnt
NetPath 118
CTBP1
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Wnt signaling pathway
KEGG 135
CTBP1
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Wnt signaling pathway
PANTHER 250
CTBP1
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Pathways in cancer
KEGG 321
CTBP1
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EGFR1
NetPath 475
Target Gene Expression Analysis
Expression Atlas of CTBP1