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T(co)F Overview
T(co)F: STAT2
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: STAT domain factors
T(co)F Superclass: Immunoglobulin fold
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR469EFL
Platform: -
Pubmed ID: 22955616

STAT2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of STAT2
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of STAT2

Upstream Pathway Annotation of STAT2
T(co)F Pathway Name Source Gene Number
STAT2
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Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )
INOH 8
STAT2
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Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )
INOH 8
STAT2
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Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram )
INOH 14
STAT2
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IFN alpha signaling pathway((JAK1 TYK2 STAT1 STAT2) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) )
INOH 20
STAT2
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Regulation of IFNA signaling
Reactome 26
STAT2
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IL27-mediated signaling events
PID 26
STAT2
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Hs_Interferon_type_I_signaling_pathways_WP585_85198
WikiPathways 35
STAT2
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GMCSF-mediated signaling events
PID 38
STAT2
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Interferon alpha/beta signaling
Reactome 67
STAT2
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Interleukin signaling pathway
PANTHER 86
STAT2
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CXCR4-mediated signaling events
PID 87
STAT2
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JAK-STAT pathway and regulation pathway ( JAK-STAT pathway and regulation pathway Diagram )
INOH 97
STAT2
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EGF receptor signaling pathway
PANTHER 109
STAT2
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PDGF signaling pathway
PANTHER 113
STAT2
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Hepatitis C
KEGG 134
STAT2
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Jak-STAT signaling pathway
KEGG 149
STAT2
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Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram )
INOH 178
STAT2
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Chemokine signaling pathway
KEGG 187
STAT2
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EGFR1
NetPath 475
Target Gene Expression Analysis
Expression Atlas of STAT2