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T(co)F Overview
T(co)F: ELK1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: MDA-MB-231
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE18849
Platform: GPL4133
Pubmed ID: 20005852

ELK1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of ELK1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of ELK1

Upstream Pathway Annotation of ELK1
T(co)F Pathway Name Source Gene Number
ELK1
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ERK cascade ( EGF signaling pathway Diagram )
INOH 6
ELK1
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ERK cascade ( HGF signaling pathway )
INOH 6
ELK1
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ERK cascade ( VEGF signaling pathway )
INOH 6
ELK1
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ERK cascade ( PDGF signaling pathway )
INOH 7
ELK1
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Hs_G_Protein_Signaling_Pathways_WP35_88601
WikiPathways 8
ELK1
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ERK cascade ( FGF signaling pathway )
INOH 8
ELK1
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ERK cascade ( IGF1 signaling pathway )
INOH 8
ELK1
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ERK cascade ( Insulin receptor signaling (D. melanogaster) )
INOH 8
ELK1
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ERK cascade ( Insulin receptor signaling (Mammal) )
INOH 8
ELK1
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ERK cascade ( NGF signaling pathway )
INOH 8
ELK1
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Hs_Estrogen_signaling_pathway_WP712_78491
WikiPathways 13
ELK1
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Hs_Serotonin_Receptor_2_and_ELK-SRF-GATA4_signaling_WP732_80010
WikiPathways 13
ELK1
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Ras signaling in the CD4+ TCR pathway
PID 14
ELK1
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Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438
WikiPathways 15
ELK1
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ERK/MAPK targets
Reactome 17
ELK1
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ERK cascade ( FGF8 signaling (Mouse) )
INOH 17
ELK1
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ERK cascade ( FGF8 signaling (Xenopus) )
INOH 17
ELK1
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FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) )
INOH 18
ELK1
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FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) )
INOH 20
ELK1
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Hs_Cytokines_and_Inflammatory_Response_WP530_79331
WikiPathways 21
ELK1
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PDGFR-alpha signaling pathway
PID 22
ELK1
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Oxidative stress response
PANTHER 23
ELK1
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S1P2 pathway
PID 26
ELK1
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Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade
PANTHER 29
ELK1
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p38 MAPK pathway
PANTHER 31
ELK1
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Prion diseases
KEGG 34
ELK1
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Hs_Structural_Pathway_of_Interleukin_1_(IL-1)_WP2637_87707
WikiPathways 34
ELK1
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Angiotensin_II-stimulated_signaling_through_G_proteins_and_beta-arrestin
PANTHER 34
ELK1
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HIF-2-alpha transcription factor network
PID 34
ELK1
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Trk receptor signaling mediated by the MAPK pathway
PID 34
ELK1
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Hs_IL-5_Signaling_Pathway_WP127_78498
WikiPathways 35
ELK1
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Hs_Leptin_signaling_pathway_WP2034_89856
WikiPathways 37
ELK1
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Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
SMPDB 37
ELK1
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ID
NetPath 38
ELK1
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Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
SMPDB 38
ELK1
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Hs_IL-4_Signaling_Pathway_WP395_89828
WikiPathways 41
ELK1
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Toll receptor signaling pathway
PANTHER 44
ELK1
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Angiopoietin receptor Tie2-mediated signaling
PID 50
ELK1
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Endometrial cancer
KEGG 52
ELK1
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Hs_MAPK_Signaling_Pathway_WP382_79951
WikiPathways 58
ELK1
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IL5
NetPath 59
ELK1
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Ras Pathway
PANTHER 69
ELK1
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Downstream signaling in nave CD8+ T cells
PID 69
ELK1
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BCR signaling pathway
PID 70
ELK1
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Leishmaniasis
KEGG 71
ELK1
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Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900
WikiPathways 71
ELK1
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IL4
NetPath 75
ELK1
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Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803
WikiPathways 80
ELK1
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IL2
NetPath 81
ELK1
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ErbB signaling pathway
KEGG 83
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Parkinson disease
PANTHER 85
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Interleukin signaling pathway
PANTHER 86
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
GnRH signaling pathway
KEGG 98
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Leptin
NetPath 98
ELK1
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KitReceptor
NetPath 104
ELK1
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Prolactin
NetPath 105
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
ErbB1 downstream signaling
PID 105
ELK1
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Hs_EGF-EGFR_Signaling_Pathway_WP437_79266
WikiPathways 107
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGF signaling pathway
PANTHER 113
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGFR-beta signaling pathway
PID 125
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Insulin signaling pathway
KEGG 134
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
BCR
NetPath 161
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Focal adhesion
KEGG 197
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
MAPK signaling pathway
KEGG 264
ELK1
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
EGFR1
NetPath 475
Target Gene Expression Analysis
Expression Atlas of ELK1