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T(co)F Overview
T(co)F: FOSL1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Basic leucine zipper factors (bZIP)
T(co)F Superclass: Basic domains
Biosample Name: BT549
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 4
# of Treat: 3
Data Source: GEO
Profile ID: GSE46440
Platform: GPL11532
Pubmed ID: 24830720

FOSL1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of FOSL1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of FOSL1

Upstream Pathway Annotation of FOSL1
T(co)F Pathway Name Source Gene Number
FOSL1
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Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling (JNK cascade) )
INOH 5
FOSL1
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Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling )
INOH 5
FOSL1
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JNK cascade ( CD4 T cell receptor signaling )
INOH 10
FOSL1
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JNK cascade ( CD4 T cell receptor signaling (JNK cascade) )
INOH 12
FOSL1
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Calcium signaling in the CD4+ TCR pathway
PID 29
FOSL1
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Validated transcriptional targets of AP1 family members Fra1 and Fra2
PID 37
FOSL1
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
PID 50
FOSL1
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Downstream signaling in nave CD8+ T cells
PID 69
FOSL1
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AP-1 transcription factor network
PID 71
FOSL1
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Validated targets of C-MYC transcriptional activation
PID 80
FOSL1
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TGF-beta signaling pathway
PANTHER 88
FOSL1
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Wnt signaling pathway
KEGG 135
Target Gene Expression Analysis
Expression Atlas of FOSL1