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T(co)F Overview
T(co)F: NFATC3
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: beta-Scaffold Factors
Biosample Name: CD4+ T cells
Tissue Type: Peripheral_blood
Biosample Type: Primary cell
# of Control: 8
# of Treat: 4
Data Source: GEO
Profile ID: GSE46333
Platform: GPL14550
Pubmed ID: 24401939

NFATC3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NFATC3
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NFATC3

Upstream Pathway Annotation of NFATC3
T(co)F Pathway Name Source Gene Number
NFATC3
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Signaling by Wnt
Reactome 10
NFATC3
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CLEC7A (Dectin-1) induces NFAT activation
Reactome 13
NFATC3
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Calcium signaling in the CD4+ TCR pathway
PID 29
NFATC3
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Axon guidance mediated by netrin
PANTHER 30
NFATC3
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Validated transcriptional targets of AP1 family members Fra1 and Fra2
PID 37
NFATC3
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FCERI mediated Ca+2 mobilization
Reactome 41
NFATC3
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FOXM1 transcription factor network
PID 43
NFATC3
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
PID 50
NFATC3
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
PID 54
NFATC3
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Downstream signaling in nave CD8+ T cells
PID 69
NFATC3
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VEGF signaling pathway
KEGG 70
NFATC3
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B cell receptor signaling pathway
KEGG 70
NFATC3
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Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900
WikiPathways 71
NFATC3
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AP-1 transcription factor network
PID 71
NFATC3
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T cell receptor signaling pathway
KEGG 105
NFATC3
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Natural killer cell mediated cytotoxicity
KEGG 125
NFATC3
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Axon guidance
KEGG 126
NFATC3
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Wnt signaling pathway
KEGG 135
NFATC3
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BCR
NetPath 161
NFATC3
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Inflammation mediated by chemokine and cytokine signaling pathway
PANTHER 189
NFATC3
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Wnt signaling pathway
PANTHER 250
Target Gene Expression Analysis
Expression Atlas of NFATC3