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T(co)F Overview
T(co)F: GLI2
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: U2OS
Tissue Type: Bone_marrow
Biosample Type: Cell line
# of Control: 1
# of Treat: 1
Data Source: GEO
Profile ID: GSE42903
Platform: GPL6244
Pubmed ID: -

GLI2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of GLI2
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of GLI2

Upstream Pathway Annotation of GLI2
T(co)F Pathway Name Source Gene Number
GLI2
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GLI proteins bind promoters of Hh responsive genes to promote transcription
Reactome 7
GLI2
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Signaling without Hh ( Hedgehog signaling pathway )
INOH 7
GLI2
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Ci/Gli processing signaling ( Hedgehog signaling pathway )
INOH 17
GLI2
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Signaling events mediated by the Hedgehog family
PID 24
GLI2
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Hedgehog
NetPath 39
GLI2
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Hedgehog 'off' state
Reactome 43
GLI2
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Hedgehog signaling events mediated by Gli proteins
PID 49
GLI2
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Basal cell carcinoma
KEGG 51
GLI2
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Hedgehog signaling pathway
KEGG 53
GLI2
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Degradation of GLI2 by the proteasome
Reactome 59
GLI2
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Hedgehog 'on' state
Reactome 72
GLI2
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Pathways in cancer
KEGG 321
Target Gene Expression Analysis
Expression Atlas of GLI2