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T(co)F Overview
T(co)F: FOS
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Basic leucine zipper factors (bZIP)
T(co)F Superclass: Basic domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 6
# of Treat: 8
Data Source: GEO
Profile ID: GSE36586
Platform: GPL14550
Pubmed ID: 22791811

FOS- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of FOS
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of FOS

Upstream Pathway Annotation of FOS
T(co)F Pathway Name Source Gene Number
FOS
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Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling (JNK cascade) )
INOH 5
FOS
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Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling )
INOH 5
FOS
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Hs_Serotonin_and_anxiety-related_events_WP3944_90836
WikiPathways 9
FOS
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Activation of the AP-1 family of transcription factors
Reactome 10
FOS
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JNK cascade ( CD4 T cell receptor signaling )
INOH 10
FOS
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JNK cascade ( CD4 T cell receptor signaling (JNK cascade) )
INOH 12
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Estrogen_signaling_pathway_WP712_78491
WikiPathways 13
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Ras signaling in the CD4+ TCR pathway
PID 14
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGFR-alpha signaling pathway
PID 22
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
S1P2 pathway
PID 26
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade
PANTHER 29
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Calcium signaling in the CD4+ TCR pathway
PID 29
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Nongenotropic Androgen signaling
PID 31
FOS
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Osteopontin-mediated events
PID 32
FOS
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IL12 signaling mediated by STAT4
PID 33
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Structural_Pathway_of_Interleukin_1_(IL-1)_WP2637_87707
WikiPathways 34
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Trk receptor signaling mediated by the MAPK pathway
PID 34
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-5_Signaling_Pathway_WP127_78498
WikiPathways 35
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-3_Signaling_Pathway_WP286_78583
WikiPathways 35
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
GMCSF-mediated signaling events
PID 38
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
FCERI mediated MAPK activation
Reactome 40
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017
WikiPathways 41
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_IL-4_Signaling_Pathway_WP395_89828
WikiPathways 41
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
ErbB2/ErbB3 signaling events
PID 41
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
FOXM1 transcription factor network
PID 43
FOS
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Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668
WikiPathways 44
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
FOXA1 transcription factor network
PID 45
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Presenilin action in Notch and Wnt signaling
PID 46
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
RhoA signaling pathway
PID 46
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL6-mediated signaling events
PID 48
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
PID 50
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
B cell activation
PANTHER 52
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL2-mediated signaling events
PID 54
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
FGF signaling pathway
PID 55
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
ATF-2 transcription factor network
PID 59
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
T cell activation
PANTHER 60
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
TP53 Regulates Transcription of DNA Repair Genes
Reactome 61
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL12-mediated signaling events
PID 62
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Colorectal cancer
KEGG 63
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Endothelins
PID 64
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Fc-epsilon receptor I signaling in mast cells
PID 64
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
LPA receptor mediated events
PID 65
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
HIF-1-alpha transcription factor network
PID 67
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Downstream signaling in nave CD8+ T cells
PID 69
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
B cell receptor signaling pathway
KEGG 70
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_Apoptosis_Modulation_and_Signaling_WP1772_91293
WikiPathways 70
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
BCR signaling pathway
PID 70
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Regulation of Telomerase
PID 70
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Leishmaniasis
KEGG 71
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
AP-1 transcription factor network
PID 71
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Alpha6Beta4Integrin
NetPath 74
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Regulation of nuclear SMAD2/3 signaling
PID 82
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
IL6
NetPath 85
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Glucocorticoid receptor regulatory network
PID 85
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Interleukin signaling pathway
PANTHER 86
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Toll-like receptor signaling pathway
KEGG 100
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Chagas disease
KEGG 103
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Apoptosis signaling pathway
PANTHER 104
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
T cell receptor signaling pathway
KEGG 105
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Prolactin
NetPath 105
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
ErbB1 downstream signaling
PID 105
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Hs_EGF-EGFR_Signaling_Pathway_WP437_79266
WikiPathways 107
FOS
Warning: Undefined variable $tf_pathway_species in /data/html/KnockTF/search/search_sample_result.php on line 779

Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Senescence-Associated Secretory Phenotype (SASP)
Reactome 108
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Huntington disease
PANTHER 113
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGF signaling pathway
PANTHER 113
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Oxidative Stress Induced Senescence
Reactome 120
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
PDGFR-beta signaling pathway
PID 125
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Angiogenesis
PANTHER 141
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
BCR
NetPath 161
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
TGF_beta_Receptor
NetPath 220
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
TCR
NetPath 261
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
MAPK signaling pathway
KEGG 264
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
Pathways in cancer
KEGG 321
FOS
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Warning: Undefined variable $snp_id in /data/html/KnockTF/search/search_sample_result.php on line 779
EGFR1
NetPath 475
Target Gene Expression Analysis
Expression Atlas of FOS