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T(co)F Overview
T(co)F: PITX2
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Homeo domain factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: TM1
Tissue Type: Eye
Biosample Type: Primary cell
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE27275
Platform: GPL6883
Pubmed ID: -

PITX2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of PITX2
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of PITX2

Upstream Pathway Annotation of PITX2
T(co)F Pathway Name Source Gene Number
PITX2
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Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735
WikiPathways 11
PITX2
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Hs_Heart_Development_WP1591_90186
WikiPathways 28
PITX2
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Regulation of nuclear beta catenin signaling and target gene transcription
PID 80
PITX2
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TGF-beta signaling pathway
KEGG 82
Target Gene Expression Analysis
Expression Atlas of PITX2