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T(co)F Overview
T(co)F: RARA
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Nuclear receptors with C4 zinc fingers
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 4
# of Treat: 2
Data Source: GEO
Profile ID: GSE26298
Platform: GPL570
Pubmed ID: 21299862

RARA- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of RARA
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of RARA

Upstream Pathway Annotation of RARA
T(co)F Pathway Name Source Gene Number
RARA
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Signaling by Retinoic Acid
Reactome 20
RARA
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RXR and RAR heterodimerization with other nuclear receptor
PID 26
RARA
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Retinoic acid receptors-mediated signaling
PID 30
RARA
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FSH
NetPath 44
RARA
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Hs_Tryptophan_metabolism_WP465_85055
WikiPathways 45
RARA
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Nuclear Receptor transcription pathway
Reactome 51
RARA
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Acute myeloid leukemia
KEGG 53
RARA
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IL3
NetPath 84
RARA
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Activation of anterior HOX genes in hindbrain development during early embryogenesis
Reactome 120
RARA
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Pathways in cancer
KEGG 321
Target Gene Expression Analysis
Expression Atlas of RARA