SEdb 2.0
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Gene overview

Strategies/Algorithm: proximal Ensembl ID: ENSG00000141506
Gene: PIK3R5 Gene type: protein_coding
Strand: - External links:
Genomic region: chr17:8878911-8965712 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_032100745 chr17:8830924-8867846 Sample_02_0321 Peripheral blood MO1043_ICN1_HA_H3K27Ac_b 745 6 1090 52 2 45 910 PIK3R6,PIK3R5,MFSD6L
SE_02_078400479 chr17:8831439-8865835 Sample_02_0784 Blood OSU-CLL 479 10 1012 48 2 38 809 PIK3R6,MFSD6L,PIK3R5
SE_02_047600865 chr17:8839512-8876174 Sample_02_0476 iPSCs hiPSC derived hepatocyte-like cells 865 11 1064 65 1 24 267 PIK3R6,MFSD6L,PIK3R5
SE_02_149200751 chr17:8842100-8874674 Sample_02_1492 Peripheral blood CD34+ derived peripheral blood-derived mast cells 751 6 932 58 1 22 196 PIK3R6,MFSD6L,PIK3R5
SE_02_142900593 chr17:8842358-8869218 Sample_02_1429 Blood GM12878_WT 593 8 769 42 1 19 196 PIK3R6,MFSD6L,PIK3R5,CCDC42,SPDYE4,AURKB
SE_02_075400272 chr17:8846812-8876128 Sample_02_0754 Embryo ES-derived progenitors Pancreatic Progenitors 1 WT 272 4 853 51 0 19 196 PIK3R6,MFSD6L,PIK3R5
SE_02_075700639 chr17:8846859-8875976 Sample_02_0757 Embryo ES-derived progenitors_FOXA2 -/- 639 5 849 51 0 19 196 PIK3R6,MFSD6L,PIK3R5
SE_02_078300999 chr17:8850038-8865969 Sample_02_0783 Blood MEC2 999 6 464 20 0 5 10 PIK3R6,PIK3R5
SE_02_139200475 chr17:8853669-8868722 Sample_02_1392 Peripheral blood Mac-2A_ALK- 475 2 456 21 0 11 107 PIK3R6,PIK3R5
SE_02_104300199 chr17:8856348-8997926 Sample_02_1043 Peripheral blood Peripheral blood cells_CTCL1200 199 63 4009 233 13 293 2308 PIK3R5,PIK3R6,NTN1
SE_02_153000060 chr17:8857282-8976106 Sample_02_1530 Peripheral blood neutrophils_0BA0X 60 27 3357 210 12 250 2308 PIK3R5,PIK3R6,NTN1
SE_02_104700509 chr17:8859318-8917026 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 509 26 1682 135 10 144 2168 PIK3R5,PIK3R6
SE_02_104800572 chr17:8873827-8917062 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 572 17 1255 111 10 129 2061 PIK3R5,PIK3R6
SE_02_069700141 chr17:8874372-8917342 Sample_02_0697 Lung NCI-H1048-cas9_sgHROSA 141 12 1249 108 10 129 2061 PIK3R5,PIK3R6
SE_02_068500085 chr17:8874603-8917204 Sample_02_0685 Lung NCI-H1048_no infection 85 10 1239 105 10 129 2061 PIK3R5,PIK3R6
SE_02_104900136 chr17:8875667-8963748 Sample_02_1049 Peripheral blood CD4+ cell_ROMI 136 63 2470 145 11 188 2061 PIK3R5,PIK3R6
SE_02_078300742 chr17:8891646-8959331 Sample_02_0783 Blood MEC2 742 22 1841 80 2 111 486 PIK3R5,PIK3R6
SE_02_119100174 chr17:8894328-8967828 Sample_02_1191 Brain GBM25 174 23 2014 91 2 144 532 PIK3R5,PIK3R6
SE_02_133000452 chr17:8894398-8968034 Sample_02_1330 Blood AMU-AML1 452 13 2015 90 2 144 532 PIK3R5,PIK3R6
SE_02_115600056 chr17:8894558-8965685 Sample_02_1156 Peripheral blood Day6 Plasmablast CD23- memory B cell 56 29 1950 84 2 118 463 PIK3R5,PIK3R6
SE_02_115700071 chr17:8894719-8962229 Sample_02_1157 Peripheral blood Day6 Plasmablast CD23- memory B cell_G9A-Inhibited 71 31 1852 79 2 108 392 PIK3R5,PIK3R6
SE_02_092800116 chr17:8897818-8971269 Sample_02_0928 Peripheral blood neutrophils_Ecoli 116 24 2012 100 3 136 532 PIK3R5,PIK3R6,NTN1
SE_02_146000690 chr17:8899072-8955120 Sample_02_1460 Blood Mutz-3 690 8 1538 66 2 91 392 PIK3R5,PIK3R6
SE_02_131500144 chr17:8899095-8968503 Sample_02_1315 Brain hMGLs_INPP5D SNP 144 15 1928 86 3 135 532 PIK3R5,PIK3R6
SE_02_134800041 chr17:8900200-8968353 Sample_02_1348 Leukophereses leukophereses_p408 41 18 1888 81 2 131 532 PIK3R5,PIK3R6
SE_02_135000070 chr17:8900370-8968620 Sample_02_1350 Leukophereses leukophereses_p456 70 21 1889 81 2 131 532 PIK3R5,PIK3R6
SE_02_131300158 chr17:8900478-8968362 Sample_02_1313 Brain hMGLs_CD33_SNP 158 17 1881 80 2 131 532 PIK3R5,PIK3R6
SE_02_093000359 chr17:8900593-8967891 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 359 31 1864 77 1 129 532 PIK3R5,PIK3R6
SE_02_134500159 chr17:8904913-8970517 Sample_02_1345 Leukophereses leukophereses_p358 159 30 1805 86 2 116 480 PIK3R5,PIK3R6
SE_02_145900046 chr17:8908104-8964156 Sample_02_1459 Pancreas THP1+PANC1_shCTCF 46 10 1560 59 1 78 241 PIK3R5,PIK3R6
SE_02_157300750 chr17:8909626-8968018 Sample_02_1573 Endothelial Undifferentiated Pleomorphic Sarcoma 750 16 1619 65 1 107 299 PIK3R5,PIK3R6
SE_02_117400488 chr17:8909668-8967995 Sample_02_1174 Brain GBM02 488 17 1618 65 1 107 299 PIK3R5,PIK3R6
SE_02_092900252 chr17:8909759-8967861 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 252 32 1615 65 1 107 299 PIK3R5,PIK3R6
SE_02_081601020 chr17:8910128-8967922 Sample_02_0816 Ovary Clear cell ovarian cancer 1020 12 1607 65 1 107 299 PIK3R5,PIK3R6
SE_02_145800112 chr17:8910264-8968172 Sample_02_1458 Pancreas THP1+PANC1_shNC 112 12 1606 63 1 109 299 PIK3R5,PIK3R6
SE_02_149500027 chr17:8910385-8935894 Sample_02_1495 Other monocyte-derived dendritic cells_R848_1h 27 12 694 23 0 24 159 PIK3R5,PIK3R6
SE_02_152900091 chr17:8913438-8971319 Sample_02_1529 Peripheral blood neutrophils_0BC75 91 20 1591 73 2 100 140 PIK3R5,PIK3R6,NTN1
SE_02_010400096 chr17:8914377-8970663 Sample_02_0104 Blood neutrophils 96 13 1539 70 2 98 140 PIK3R5,PIK3R6
SE_02_017300869 chr17:8914387-8949406 Sample_02_0173 Lung IMR-90_senescent 869 9 956 36 1 44 0 PIK3R5,PIK3R6,NTN1
SE_02_153100102 chr17:8914511-8970492 Sample_02_1531 Peripheral blood neutrophils_0B9ZK 102 19 1532 70 2 98 140 PIK3R5,PIK3R6,NTN1
SE_02_092700106 chr17:8914569-8968652 Sample_02_0927 Peripheral blood neutrophils_US 106 17 1494 60 2 98 140 PIK3R5,PIK3R6,NTN1
SE_01_005200054 chr17:8914591-8970797 Sample_01_0052 Blood neutrophil 54 10 1535 69 2 98 140 PIK3R5,PIK3R6
SE_01_008400519 chr17:8914885-8968200 Sample_01_0084 Spleen spleen 519 10 1469 55 1 98 140 PIK3R5,PIK3R6
SE_00_000600071 chr17:8915095-8968334 Sample_00_0006 Blood CD14-positive-monocyte 71 7 1470 57 2 96 140 PIK3R5,PIK3R6
SE_02_082600509 chr17:8915206-8961552 Sample_02_0826 Stomach gastric tumor 509 28 1274 43 1 59 0 PIK3R5,PIK3R6
SE_02_134900080 chr17:8915238-8968218 Sample_02_1349 Leukophereses leukophereses_p411 80 15 1462 55 1 96 140 PIK3R5,PIK3R6
SE_02_117500098 chr17:8915296-8968069 Sample_02_1175 Brain GBM03 98 13 1457 54 1 94 140 PIK3R5,PIK3R6
SE_02_149400196 chr17:8915341-8936039 Sample_02_1494 Other monocyte-derived dendritic cells_0h 196 7 562 15 0 11 0 PIK3R5,PIK3R6
SE_02_149600402 chr17:8915377-8936623 Sample_02_1496 Other monocyte-derived dendritic cells_R848_24h 402 14 566 15 0 11 0 PIK3R5,PIK3R6
SE_02_034200593 chr17:8915418-8968767 Sample_02_0342 Liver HSPCs_F0 593 7 1474 58 2 96 140 PIK3R5,PIK3R6
SE_02_014800205 chr17:8915422-8959312 Sample_02_0148 Blood CD8_T_cells 205 8 1207 40 1 55 0 PIK3R5,PIK3R6
SE_01_010400688 chr17:8915637-8967781 Sample_01_0104 Lung upper lobe of left lung 688 10 1433 51 1 93 140 PIK3R5,PIK3R6,NTN1
SE_02_131200166 chr17:8915684-8968568 Sample_02_1312 Brain hMGLs_WT 166 11 1458 57 2 96 140 PIK3R5,PIK3R6
SE_02_014700003 chr17:8915689-8967950 Sample_02_0147 Blood CD4_T_cells 3 11 1437 53 1 94 140 PIK3R5,PIK3R6
SE_00_005500351 chr17:8915852-8967801 Sample_00_0055 Spleen spleen 34y 351 12 1429 51 1 93 140 PIK3R5,PIK3R6
SE_02_142900279 chr17:8915943-8994234 Sample_02_1429 Blood GM12878_WT 279 16 2165 94 2 129 140 PIK3R5,NTN1,PIK3R6
SE_02_002300190 chr17:8915959-8964108 Sample_02_0023 Blood CD8donorC 190 20 1327 45 1 59 0 PIK3R5,PIK3R6
SE_02_078400238 chr17:8918983-8997997 Sample_02_0784 Blood OSU-CLL 238 20 2207 92 3 149 140 PIK3R5,NTN1
SE_02_013200746 chr17:8922242-8966362 Sample_02_0132 Lung 1015_CL 746 8 1205 39 1 79 140 PIK3R5
SE_02_034500347 chr17:8922424-8967955 Sample_02_0345 Blood AML8 347 6 1246 45 1 94 140 PIK3R5
SE_02_045700319 chr17:8922876-8966201 Sample_02_0457 Th17 lymphocytes Th17-IL-10- Day 5 319 14 1178 38 1 79 140 PIK3R5
SE_02_002200233 chr17:8924658-8966198 Sample_02_0022 Blood CD8donorA 233 17 1139 37 1 79 140 PIK3R5
SE_00_004400544 chr17:8933478-8966557 Sample_00_0044 Cord blood T-cell 544 6 923 35 1 81 140 PIK3R5
SE_00_000800507 chr17:8934034-8966760 Sample_00_0008 Blood CD4-positive-alpha-beta-memory-T-cell 507 5 915 36 1 81 140 PIK3R5
SE_02_045400695 chr17:8934569-8966189 Sample_02_0454 Th17 lymphocytes Th17-IL-10+ Day 0 695 11 884 34 1 78 140 PIK3R5
SE_02_104000272 chr17:8934916-8964391 Sample_02_1040 Peripheral blood CD4+ cells_CTCL1126 272 21 838 33 1 58 0 PIK3R5
SE_02_104200340 chr17:8935118-8963423 Sample_02_1042 Peripheral blood CD4+ cells_CTCL1137 340 18 801 32 1 58 0 PIK3R5
SE_02_104603051 chr17:8935625-8972842 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 3051 10 1041 55 2 85 140 PIK3R5,NTN1
SE_02_104801325 chr17:8935659-8960738 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 1325 11 701 27 1 45 0 PIK3R5
SE_02_104701447 chr17:8935659-8963454 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 1447 11 790 32 1 48 0 PIK3R5
SE_02_059200554 chr17:8939018-8955448 Sample_02_0592 PBMCs adult CD4+CD25hiCD127lo regulatory T cells 554 8 460 21 1 37 0 PIK3R5
SE_02_104400408 chr17:8939720-8955379 Sample_02_1044 Peripheral blood CD4+ cells_CTCL409 408 9 448 21 1 32 0 PIK3R5
SE_02_131600537 chr17:8944622-8968694 Sample_02_1316 Brain hMGLs_TREM2-R47H 537 8 682 30 2 63 140 PIK3R5
SE_02_131700391 chr17:8944754-8968069 Sample_02_1317 Brain hMGLs_SORL1-KO 391 5 657 25 1 61 140 PIK3R5
SE_02_131400313 chr17:8953293-8968513 Sample_02_1314 Brain hMGLs_TREM2-KO 313 6 428 21 1 50 140 PIK3R5
SE_02_149500127 chr17:8953442-8968538 Sample_02_1495 Other monocyte-derived dendritic cells_R848_1h 127 7 424 21 1 50 140 PIK3R5
SE_02_068500105 chr17:8953610-8978771 Sample_02_0685 Lung NCI-H1048_no infection 105 4 709 43 1 80 140 PIK3R5,NTN1
SE_02_131800491 chr17:8953951-8968452 Sample_02_1318 Brain hMGLs_SORL1-A528T 491 3 416 21 1 47 140 PIK3R5
SE_02_099301050 chr17:8954095-8969957 Sample_02_0993 Blood MOLM-13_empty 1050 5 442 26 1 47 140 PIK3R5
SE_02_069700441 chr17:8960909-8982553 Sample_02_0697 Lung NCI-H1048-cas9_sgHROSA 441 7 633 44 1 68 140 PIK3R5,NTN1
SE_02_143001002 chr17:8964081-8968244 Sample_02_1430 Blood Kasumi-3_mock-infected 1002 1 111 9 1 37 140 PIK3R5
SE_02_155900687 chr17:8991906-9028602 Sample_02_1559 Gastrointestinal Stromal GIST-8_PDGFRA e18 687 9 996 30 9 403 423 NTN1,PIK3R5
SE_02_097100241 chr17:9002256-9030333 Sample_02_0971 Brain H3.3K27M_XPS124018_xenograft 241 12 738 36 9 419 423 NTN1,PIK3R5
SE_02_075200847 chr17:9002369-9039143 Sample_02_0752 Embryo ES-derived progenitors_DE_wild type 847 8 987 58 9 445 423 NTN1,PIK3R5
Genomic distribution of SEs associated with PIK3R5
Genome Browser

The strength of the tissue affected by the gene

Expression of PIK3R5

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)