SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000133246
Gene: PRAM1 Gene type: protein_coding
Strand: - External links:
Genomic region: chr19:8490056-8502640 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_01_009500150 chr19:8441327-8506664 Sample_01_0095 Embryo neuroepithelial stem cell stably expressing HES5 originated from H9 150 21 1908 159 10 312 2321 HNRNPM,PRAM1,ZNF414,MARCH2
SE_02_138200426 chr19:8444844-8512241 Sample_02_1382 Pancreas Pancreatic cancer cells_Triptolide 426 20 2002 186 10 335 2792 HNRNPM,ZNF414,PRAM1,MARCH2
SE_02_119100639 chr19:8463057-8527137 Sample_02_1191 Brain GBM25 639 12 2027 225 10 243 3700 ZNF414,HNRNPM,MYO1F,PRAM1,MARCH2
SE_02_075000358 chr19:8469616-8526679 Sample_02_0750 Lymphoma Rec-1_GSI 358 18 1833 203 10 189 3366 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_111200243 chr19:8470278-8526393 Sample_02_1112 T lymphocyte THP-6 T-ALL 243 18 1803 199 10 181 3289 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_010100849 chr19:8471510-8519125 Sample_02_0101 Peripheral blood Macrophages_GM-CSF_72h_IFN-y 849 6 1477 179 8 158 2698 ZNF414,PRAM1,HNRNPM
SE_02_131500502 chr19:8471782-8506327 Sample_02_1315 Brain hMGLs_INPP5D SNP 502 10 1074 98 7 103 1784 HNRNPM,PRAM1,ZNF414
SE_01_002400542 chr19:8472081-8521822 Sample_01_0024 Blood CD14-positive-monocyte 542 10 1536 186 9 164 2919 ZNF414,MYO1F,PRAM1,HNRNPM
SE_02_093000803 chr19:8472384-8526346 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 803 17 1725 195 10 177 3215 ZNF414,HNRNPM,MYO1F,PRAM1,MARCH2,ADAMTS10,RAB11B
SE_02_131800490 chr19:8472653-8506254 Sample_02_1318 Brain hMGLs_SORL1-A528T 490 10 1048 93 7 103 1784 HNRNPM,PRAM1,ZNF414
SE_02_131400543 chr19:8472657-8506363 Sample_02_1314 Brain hMGLs_TREM2-KO 543 11 1052 94 7 103 1784 HNRNPM,PRAM1,ZNF414
SE_02_131300429 chr19:8472682-8506306 Sample_02_1313 Brain hMGLs_CD33_SNP 429 16 1050 94 7 103 1784 HNRNPM,PRAM1,ZNF414
SE_02_131700343 chr19:8472787-8506169 Sample_02_1317 Brain hMGLs_SORL1-KO 343 10 1045 91 7 103 1784 HNRNPM,PRAM1,ZNF414
SE_02_083400152 chr19:8472791-8519135 Sample_02_0834 Bone marrow TEX-HIST1H3F-WT-Rx_cells 152 8 1440 175 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_131600375 chr19:8472832-8506460 Sample_02_1316 Brain hMGLs_TREM2-R47H 375 11 1054 96 7 103 1784 HNRNPM,PRAM1,ZNF414
SE_02_103400336 chr19:8473062-8517529 Sample_02_1034 Blood AML cell 336 4 1385 170 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_057500359 chr19:8473115-8518931 Sample_02_0575 Blood MOLM13_sgLKB1e2 359 21 1427 174 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_084100283 chr19:8473121-8519599 Sample_02_0841 Blood THP-1_untr 283 7 1440 177 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_058100270 chr19:8473242-8518860 Sample_02_0581 Blood MOLM13_empty_HG 270 17 1424 174 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_058200411 chr19:8473243-8518854 Sample_02_0582 Blood MOLM13_SIK3TQ_HG 411 8 1423 174 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_010400308 chr19:8473296-8518609 Sample_02_0104 Blood neutrophils 308 8 1415 174 8 158 2691 ZNF414,PRAM1,HNRNPM
SE_02_057700397 chr19:8473315-8518789 Sample_02_0577 Blood MOLM13_empty 397 10 1421 174 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_02_057400566 chr19:8473329-8518917 Sample_02_0574 Blood MOLM-13_sgNeg2 566 17 1423 174 8 158 2691 HNRNPM,ZNF414,PRAM1
SE_01_005200202 chr19:8473354-8519259 Sample_01_0052 Blood neutrophil 202 3 1427 176 8 158 2691 ZNF414,PRAM1,HNRNPM
SE_02_033700437 chr19:8473488-8518433 Sample_02_0337 Haematopoietic and lymphoid tissue MV411_untreat 437 8 1407 174 8 158 2688 ZNF414,PRAM1,HNRNPM
SE_02_025500106 chr19:8473540-8519171 Sample_02_0255 Haematopoietic and lymphoid tissue MOLM13 106 7 1418 175 8 158 2686 ZNF414,PRAM1,HNRNPM
SE_02_025600373 chr19:8473547-8519079 Sample_02_0256 Peripheral blood MV411 373 8 1417 175 8 158 2686 ZNF414,PRAM1,HNRNPM
SE_02_057800297 chr19:8473550-8519088 Sample_02_0578 Blood MOLM-13_sgSIK3e4 297 17 1417 175 8 158 2686 HNRNPM,ZNF414,PRAM1
SE_02_083700143 chr19:8473805-8519296 Sample_02_0837 Bone marrow TEX-Luciferase-Rx_cells 143 9 1418 176 8 157 2669 HNRNPM,ZNF414,PRAM1
SE_02_099500371 chr19:8473844-8518897 Sample_02_0995 Blood MOLM-13_empty vector 371 13 1409 174 8 157 2665 HNRNPM,ZNF414,PRAM1
SE_02_099400378 chr19:8473858-8518786 Sample_02_0994 Blood MOLM13_SIK3TQ 378 18 1407 174 8 157 2659 HNRNPM,ZNF414,PRAM1
SE_02_135000517 chr19:8473924-8520036 Sample_02_1350 Leukophereses leukophereses_p456 517 12 1435 179 8 156 2658 HNRNPM,ZNF414,PRAM1
SE_02_099300284 chr19:8473955-8518891 Sample_02_0993 Blood MOLM-13_empty 284 15 1401 174 8 156 2658 HNRNPM,ZNF414,PRAM1
SE_02_092800546 chr19:8473961-8518390 Sample_02_0928 Peripheral blood neutrophils_Ecoli 546 10 1388 174 8 156 2658 HNRNPM,ZNF414,PRAM1,ADAMTS10
SE_00_005500272 chr19:8474090-8526470 Sample_00_0055 Spleen spleen 34y 272 19 1676 193 10 175 3195 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_051700812 chr19:8478388-8527032 Sample_02_0517 Esophagus TE5 812 8 1585 183 9 178 3293 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_003900989 chr19:8480633-8527018 Sample_02_0039 Embryo AFG 989 8 1524 174 8 178 3288 ZNF414,MYO1F,PRAM1,HNRNPM
SE_00_002200816 chr19:8480652-8527208 Sample_00_0022 Lung lung_30y 816 10 1527 175 8 178 3321 ZNF414,MYO1F,PRAM1,HNRNPM,PRA1
SE_02_001900170 chr19:8480669-8526864 Sample_02_0019 Embryo Neural crest cells 170 11 1518 174 8 177 3262 ZNF414,MYO1F,PRAM1,HNRNPM
SE_02_153000342 chr19:8480686-8507655 Sample_02_1530 Peripheral blood neutrophils_0BA0X 342 1 879 81 5 98 1702 HNRNPM,PRAM1,ZNF414
SE_00_001000457 chr19:8480711-8526730 Sample_00_0010 Embryo endodermal-cell 457 9 1514 174 8 174 3231 ZNF414,MYO1F,PRAM1,HNRNPM
SE_00_004000699 chr19:8480764-8526906 Sample_00_0040 Spleen spleen_30y 699 12 1518 174 8 178 3266 ZNF414,MYO1F,PRAM1,HNRNPM
SE_02_157201144 chr19:8480875-8526815 Sample_02_1572 iPSCs FiPSC 1144 10 1512 174 8 175 3256 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_005600728 chr19:8480941-8527116 Sample_02_0056 Mammary gland HMEC 728 7 1520 174 8 178 3310 ZNF414,MYO1F,PRAM1,HNRNPM
SE_02_012800333 chr19:8481153-8521790 Sample_02_0128 Haematopoietic and lymphoid tissue ALL-SIL 333 13 1293 162 7 159 2835 ZNF414,MYO1F,PRAM1,HNRNPM
SE_01_010400615 chr19:8481177-8526954 Sample_01_0104 Lung upper lobe of left lung 615 11 1507 174 8 178 3278 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_152900390 chr19:8482969-8508950 Sample_02_1529 Peripheral blood neutrophils_0BC75 390 1 836 79 5 98 1701 HNRNPM,PRAM1,ZNF414
SE_00_000600817 chr19:8483429-8492152 Sample_00_0006 Blood CD14-positive-monocyte 817 1 285 18 2 75 977 PRAM1,HNRNPM,ZNF414
SE_02_092700361 chr19:8483677-8519046 Sample_02_0927 Peripheral blood neutrophils_US 361 7 1130 146 5 150 2565 HNRNPM,ZNF414,PRAM1,ADAMTS10
SE_02_153100450 chr19:8483700-8505474 Sample_02_1531 Peripheral blood neutrophils_0B9ZK 450 1 713 59 4 95 1658 HNRNPM,PRAM1,ZNF414
SE_02_081601144 chr19:8484062-8526947 Sample_02_0816 Ovary Clear cell ovarian cancer 1144 11 1413 162 7 175 3232 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_034200156 chr19:8484358-8519010 Sample_02_0342 Liver HSPCs_F0 156 7 1111 141 5 150 2565 ZNF414,PRAM1,HNRNPM
SE_02_010000727 chr19:8484479-8519303 Sample_02_0100 Peripheral blood Macrophages_GM-CSF_72h 727 4 1115 142 5 150 2565 ZNF414,PRAM1,HNRNPM
SE_02_111900335 chr19:8484609-8519021 Sample_02_1119 Blood KBM7 335 10 1102 140 5 150 2565 HNRNPM,ZNF414,PRAM1
SE_02_119700897 chr19:8484629-8526884 Sample_02_1197 Brain GBM33 897 11 1391 160 7 174 3219 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_104600983 chr19:8484699-8527696 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 983 14 1412 162 7 181 3368 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_082600911 chr19:8484781-8525563 Sample_02_0826 Stomach gastric tumor 911 12 1348 159 7 169 3037 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_083600204 chr19:8485123-8519178 Sample_02_0836 Bone marrow TEX-HIST1H3H-WT-Rx_cells 204 10 1089 140 5 150 2565 HNRNPM,ZNF414,PRAM1
SE_02_134200057 chr19:8485244-8518588 Sample_02_1342 Blood NB4 57 9 1073 139 5 150 2565 HNRNPM,ZNF414,PRAM1
SE_02_034300161 chr19:8485384-8519159 Sample_02_0343 Bone marrow HSPC_A0 161 7 1080 140 5 150 2565 ZNF414,PRAM1,HNRNPM
SE_02_107100379 chr19:8485449-8506631 Sample_02_1071 Blood Jurkat_WT 379 5 692 61 4 95 1650 HNRNPM,PRAM1,ZNF414
SE_02_138400493 chr19:8485462-8506336 Sample_02_1384 Other induced pluripotent stem cell derived Neuronal progenitor cell 493 7 683 59 4 95 1647 HNRNPM,PRAM1,ZNF414
SE_02_034400096 chr19:8485468-8514899 Sample_02_0344 Blood CD34 96 5 956 110 5 142 2554 ZNF414,PRAM1,HNRNPM
SE_02_083300141 chr19:8485496-8519116 Sample_02_0833 Bone marrow TEX-HIST1H3F-K27I-2-Rx_cells 141 7 1072 140 5 150 2551 HNRNPM,ZNF414,PRAM1
SE_02_083500134 chr19:8485555-8518930 Sample_02_0835 Bone marrow TEX-HIST1H3H-K27M-Rx_cells 134 9 1070 139 5 150 2542 HNRNPM,ZNF414,PRAM1
SE_02_133200279 chr19:8485597-8523251 Sample_02_1332 Blood Monomac6_CTRL 279 10 1239 153 7 167 2956 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_133100164 chr19:8485652-8518893 Sample_02_1331 Blood Molm13_CTRL 164 8 1069 139 5 147 2518 HNRNPM,ZNF414,PRAM1
SE_02_093200419 chr19:8485668-8506860 Sample_02_0932 Embryo H9 WT_1 419 4 695 63 4 91 1606 HNRNPM,PRAM1,ZNF414
SE_02_093300166 chr19:8485673-8506796 Sample_02_0933 Embryo H7 UTXKO 166 5 694 63 4 90 1603 HNRNPM,PRAM1,ZNF414
SE_02_093400422 chr19:8485717-8506538 Sample_02_0934 Embryo H7-WT 422 7 687 61 4 88 1595 HNRNPM,PRAM1,ZNF414
SE_02_143300416 chr19:8485753-8526963 Sample_02_1433 Bone A673 STAG2 null 416 20 1361 160 7 168 3163 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_033200396 chr19:8485768-8519251 Sample_02_0332 Haematopoietic and lymphoid tissue MOLM14_DMSO_9 396 4 1071 140 5 143 2488 ZNF414,PRAM1,HNRNPM
SE_02_034700074 chr19:8485884-8521887 Sample_02_0347 Blood AML11 74 7 1142 148 6 141 2690 ZNF414,MYO1F,PRAM1,HNRNPM
SE_02_050100069 chr19:8485893-8518295 Sample_02_0501 Blood HL-60_CTRL 69 11 1037 139 5 135 2461 HNRNPM,ZNF414,PRAM1
SE_02_093100617 chr19:8485949-8507163 Sample_02_0931 Embryo H9 UTXKO 617 8 691 64 4 80 1541 HNRNPM,PRAM1,ZNF414
SE_02_014400624 chr19:8485950-8518628 Sample_02_0144 Peripheral blood MV411_DMSO 624 5 1050 139 5 135 2448 ZNF414,PRAM1,HNRNPM
SE_02_062200668 chr19:8485960-8502375 Sample_02_0622 Blood EOL1_Naive 668 8 561 36 4 78 1424 HNRNPM,PRAM1,ZNF414
SE_00_003900828 chr19:8486013-8526944 Sample_00_0039 Spleen spleen_3y 828 7 1349 160 7 159 3100 ZNF414,MYO1F,PRAM1,HNRNPM
SE_02_117500385 chr19:8486014-8526382 Sample_02_1175 Brain GBM03 385 5 1332 159 7 153 2961 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_046000270 chr19:8486058-8521654 Sample_02_0460 Blood ME-1_I-10-49_6h 270 13 1131 148 6 140 2626 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_050200307 chr19:8486112-8518991 Sample_02_0502 Blood HL-60_PMA_16h 307 8 1051 140 5 129 2409 HNRNPM,ZNF414,PRAM1
SE_02_045900149 chr19:8486350-8520176 Sample_02_0459 Blood ME-1_DMSO_6h 149 13 1076 142 5 121 2354 HNRNPM,ZNF414,PRAM1
SE_02_033300225 chr19:8486381-8519165 Sample_02_0333 Haematopoietic and lymphoid tissue MOLM14_DMSO_10 225 5 1044 138 5 119 2348 ZNF414,PRAM1,HNRNPM
SE_00_004800258 chr19:8486426-8490010 Sample_00_0048 Embryo neuronal stem cell originated from H1 258 4 113 7 2 31 443 HNRNPM,ZNF414,PRAM1
SE_02_102800234 chr19:8486495-8518581 Sample_02_1028 Blood HL-60_WT 234 11 1032 137 5 119 2324 HNRNPM,ZNF414,PRAM1
SE_02_109800156 chr19:8486520-8518400 Sample_02_1098 Blood THP1_DMSO_noPMA 156 13 1026 137 5 119 2321 HNRNPM,ZNF414,PRAM1
SE_02_082100174 chr19:8486528-8519801 Sample_02_0821 Haematopoietic and lymphoid tissue SET-2_WT_GSK-LSD1 174 7 1062 142 5 119 2317 HNRNPM,ZNF414,PRAM1
SE_02_033500350 chr19:8486621-8519106 Sample_02_0335 Haematopoietic and lymphoid tissue MOLM14_CA25_12 350 5 1040 138 5 119 2310 ZNF414,PRAM1,HNRNPM
SE_02_134000847 chr19:8486669-8519075 Sample_02_1340 Blood acute myeloid leukemia 847 13 1037 138 5 119 2310 HNRNPM,ZNF414,PRAM1
SE_02_061700485 chr19:8486873-8518134 Sample_02_0617 HSPC FL CD34+CD38-/lowCD90+ HSPC 485 5 1009 137 5 119 2305 HNRNPM,ZNF414,PRAM1
SE_02_034500325 chr19:8487036-8506571 Sample_02_0345 Blood AML8 325 7 644 58 4 62 1376 PRAM1,HNRNPM,ZNF414
SE_02_139300423 chr19:8487121-8518739 Sample_02_1393 Lymph node anaplastic large cell lymphoma cells_ALK+#54 423 5 1019 136 5 117 2275 HNRNPM,ZNF414,PRAM1
SE_02_059300246 chr19:8487144-8518915 Sample_02_0593 Fetal spleenocytes fetal naive T cells 246 5 1021 136 5 117 2274 HNRNPM,ZNF414,PRAM1
SE_02_046300366 chr19:8487306-8518476 Sample_02_0463 Blood OCI-AML3 cells 366 8 1006 135 5 117 2248 HNRNPM,ZNF414,PRAM1
SE_02_046400167 chr19:8487363-8506048 Sample_02_0464 Bone marrow MOLM-13 167 6 614 52 4 62 1333 HNRNPM,PRAM1,ZNF414
SE_02_059100337 chr19:8487373-8520267 Sample_02_0591 PBMCs adult CD4+CD25-CD45RA+CD27+ naive T cells 337 9 1049 140 5 117 2237 HNRNPM,ZNF414,PRAM1,ADAMTS10
SE_02_103900110 chr19:8487439-8521716 Sample_02_1039 Peripheral blood CD4+ CD7- cells_CTCL1043 110 13 1089 143 5 122 2440 ZNF414,HNRNPM,MYO1F,PRAM1
SE_02_082000606 chr19:8487825-8517586 Sample_02_0820 Haematopoietic and lymphoid tissue SET-2_WT_DMSO 606 5 960 130 4 116 2157 HNRNPM,ZNF414,PRAM1
SE_02_003601413 chr19:8489401-8526874 Sample_02_0036 Embryo H7 1413 8 1234 153 5 112 2585 ZNF414,MYO1F,PRAM1,HNRNPM
Genomic distribution of SEs associated with PRAM1
Genome Browser

The strength of the tissue affected by the gene

Expression of PRAM1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)