SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000145632
Gene: PLK2 Gene type: protein_coding
Strand: - External links:
Genomic region: chr5:58453982-58460139 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_008700001 chr5:57730877-58305078 Sample_02_0087 Pancreas MiaPaca2 1 13 16658 323 53 1051 43 PLK2
SE_02_003301127 chr5:58007178-58022843 Sample_02_0033 Pancreas pancreatic-islets-F 1127 2 459 1 1 43 0 PLK2
SE_01_005700098 chr5:58042566-58208854 Sample_01_0057 Pancreas duct PANC-1 98 33 4838 72 30 290 43 PLK2
SE_02_003300256 chr5:58055501-58135802 Sample_02_0033 Pancreas pancreatic-islets-F 256 10 2403 51 14 166 0 PLK2
SE_02_011500098 chr5:58065265-58097235 Sample_02_0115 Mammary gland MCF-7 98 5 1037 20 3 109 0 PLK2
SE_02_035300778 chr5:58068945-58092319 Sample_02_0353 Colon HT29 778 8 702 14 2 79 0 PLK2
SE_02_016200233 chr5:58069029-58081480 Sample_02_0162 Prostate C4-2B_vehicle_24h 233 6 385 10 0 69 0 PLK2
SE_02_016900450 chr5:58069271-58081520 Sample_02_0169 Prostate LNCaP_R1881 450 2 370 9 0 69 0 PLK2
SE_02_017000292 chr5:58069353-58081524 Sample_02_0170 Prostate LNCaP_R1881_DOX 292 2 365 9 0 69 0 PLK2
SE_01_005000387 chr5:58105860-58157357 Sample_01_0050 Embryo neural-cell 387 8 1457 29 4 82 0 PLK2
SE_02_011500121 chr5:58179267-58192112 Sample_02_0115 Mammary gland MCF-7 121 1 349 3 7 14 0 PLK2
SE_02_017700398 chr5:58180257-58193189 Sample_02_0177 Urinary bladder J82 398 1 352 3 7 14 0 PLK2
SE_02_003000279 chr5:58184684-58191553 Sample_02_0030 Kidney human kidney proximal tubule cells 279 5 173 1 3 13 0 PLK2
SE_01_005700497 chr5:58227637-58282349 Sample_01_0057 Pancreas duct PANC-1 497 12 1523 4 4 160 0 PLK2
SE_02_017300465 chr5:58230872-58275404 Sample_02_0173 Lung IMR-90_senescent 465 8 1252 4 3 139 0 PLK2
SE_01_002600682 chr5:58239446-58260870 Sample_01_0026 Umbilical vein endothelial-cell-of-umbilical-vein 682 3 567 0 2 102 0 PLK2
SE_00_000301488 chr5:58240904-58274910 Sample_00_0003 Adrenal gland adrenal-gland_97d 1488 7 905 1 3 107 0 PLK2
SE_02_001101073 chr5:58256233-58267179 Sample_02_0011 Kidney A-498_wtVHL 1073 3 282 0 1 45 0 PLK2
SE_02_020400091 chr5:58362717-58390855 Sample_02_0204 Stomach IM95 91 12 790 38 1 31 0 PLK2
SE_02_009900785 chr5:58403087-58412610 Sample_02_0099 Foreskin Epidermal-Stem-Cells_shDNMT3B 785 1 261 7 0 25 0 PLK2
SE_02_009700776 chr5:58403584-58412195 Sample_02_0097 Foreskin Epidermal-Stem-Cells_shCTRL 776 3 236 7 0 25 0 PLK2
SE_02_077000493 chr5:58439432-58467451 Sample_02_0770 Ovary OVCA429_shLuc 493 12 813 71 2 139 653 PLK2,GAPT
SE_02_076700430 chr5:58440184-58463065 Sample_02_0767 Ovary OVCA429 430 8 667 52 2 134 653 PLK2,GAPT
SE_02_108800484 chr5:58440693-58462771 Sample_02_1088 Mammary gland T47D_shCtrl_45min 484 5 642 51 2 134 653 PLK2,GAPT
SE_02_000200348 chr5:58440694-58462998 Sample_02_0002 Mammary gland MCF-7_10Gygamma_2.5h 348 2 648 51 2 134 653 PLK2,GAPT
SE_02_108700304 chr5:58440722-58462748 Sample_02_1087 Mammary gland T47D_shCtrl_shRING1B_0 304 4 640 51 2 134 653 PLK2,GAPT
SE_02_040300252 chr5:58440849-58463117 Sample_02_0403 Mammary gland T-47D_untreat 252 2 646 51 2 134 653 PLK2,GAPT
SE_02_053200323 chr5:58441070-58462651 Sample_02_0532 Mammary gland T47D 323 4 624 49 2 129 653 PLK2,GAPT
SE_02_109300471 chr5:58441082-58462816 Sample_02_1093 Mammary gland T47D_shCtrl_shRING1B_24hr 471 4 628 50 2 129 653 PLK2,GAPT
SE_02_109200614 chr5:58441106-58462754 Sample_02_1092 Mammary gland T47D_shCtrl_24hr 614 5 625 50 2 129 653 PLK2,GAPT
SE_02_071300905 chr5:58441109-58462808 Sample_02_0713 Pancreas BxPC3_sgTP63 905 4 627 50 2 129 653 PLK2,GAPT
SE_02_109000371 chr5:58441114-58462699 Sample_02_1090 Mammary gland T47D_shCtrl_8hr 371 5 623 50 2 129 653 PLK2,GAPT
SE_02_108600392 chr5:58441152-58462625 Sample_02_1086 Mammary gland T47D_shCtrl_0hr 392 5 620 49 2 129 653 PLK2,GAPT
SE_02_010500653 chr5:58444280-58462917 Sample_02_0105 Skin neonatal_keratinocytes 653 2 542 43 2 128 653 PLK2,GAPT
SE_02_009900110 chr5:58444326-58463004 Sample_02_0099 Foreskin Epidermal-Stem-Cells_shDNMT3B 110 2 545 43 2 128 653 PLK2,GAPT
SE_02_008700220 chr5:58444675-58468774 Sample_02_0087 Pancreas MiaPaca2 220 1 703 61 2 128 653 PLK2,GAPT
SE_02_076900217 chr5:58444714-58463104 Sample_02_0769 Ovary HEYA8 217 8 535 42 2 128 653 PLK2,GAPT
SE_02_049200802 chr5:58444786-58463090 Sample_02_0492 Pharyng Detroit 562_LPS 802 3 535 42 2 128 653 PLK2,GAPT
SE_02_123300138 chr5:58445210-58462388 Sample_02_1233 Lung PC9_miR-4497 mimic 138 5 508 38 2 126 653 PLK2,GAPT
SE_02_075900177 chr5:58446336-58463759 Sample_02_0759 Ovary BIN-67_Control 177 3 488 41 2 128 653 PLK2,GAPT
SE_02_081100840 chr5:58446550-58462456 Sample_02_0811 Thyroid BCPAP 840 7 438 35 2 128 653 PLK2,GAPT
SE_02_127900701 chr5:58446611-58462741 Sample_02_1279 Bone Mesenchymal stem cells 701 1 443 36 2 128 653 PLK2,GAPT
SE_02_093600485 chr5:58446666-58462929 Sample_02_0936 Retinal Pigmented Epithelial RPE188_TnT 485 11 441 36 2 128 653 PLK2,GAPT
SE_02_114900271 chr5:58446697-58461002 Sample_02_1149 Kidney WT 9-12_control_Nrf2_SFN 271 3 388 32 1 125 653 PLK2,GAPT
SE_02_076201234 chr5:58446711-58463276 Sample_02_0762 Podocyte podocyte_CTL 1234 4 446 36 2 128 653 PLK2,GAPT
SE_02_011000713 chr5:58446895-58467963 Sample_02_0110 Ovaries IOE11 713 3 583 53 2 128 653 PLK2,GAPT
SE_02_093800653 chr5:58446937-58462872 Sample_02_0938 Retinal Pigmented Epithelial RPE190_TnT 653 5 434 36 2 128 653 PLK2,GAPT
SE_02_076300949 chr5:58446958-58463329 Sample_02_0763 Podocyte podocyte_DEX 949 4 446 36 2 128 653 PLK2,GAPT
SE_02_113700841 chr5:58447199-58462775 Sample_02_1137 Retinal Pigmented Epithelial RPE1-interphase 841 4 423 36 2 128 653 PLK2,GAPT
SE_02_113900755 chr5:58447207-58462868 Sample_02_1139 Retinal Pigmented Epithelial RPE1-anaphase/telophase 755 2 426 36 2 128 653 PLK2,GAPT
SE_02_113800674 chr5:58447293-58463217 Sample_02_1138 Retinal Pigmented Epithelial RPE1-prometaphase 674 3 433 36 2 128 653 PLK2,GAPT
SE_02_011500079 chr5:58449091-58462962 Sample_02_0115 Mammary gland MCF-7 79 1 376 31 2 127 653 PLK2,GAPT
SE_02_156800097 chr5:58449133-58462825 Sample_02_1568 Heart Cardiac progenitor cells 97 3 375 31 2 127 653 PLK2,GAPT
SE_02_077100326 chr5:58449205-58463348 Sample_02_0771 Ovary OVCA429_shGRHL2 326 9 386 31 2 126 653 PLK2,GAPT
SE_02_076100253 chr5:58449334-58463323 Sample_02_0761 Ovary BIN-67_SMARCA4.T910M 253 1 383 31 2 126 653 PLK2,GAPT
SE_02_138300254 chr5:58449354-58462702 Sample_02_1383 Pancreas Pancreatic cancer cells_THZ1 254 3 366 31 2 126 653 PLK2,GAPT
SE_02_076000108 chr5:58449357-58463061 Sample_02_0760 Ovary BIN-67_SMARCA4 108 1 375 31 2 126 653 PLK2,GAPT
SE_02_006300841 chr5:58449396-58463054 Sample_02_0063 Skin Keratinocytes 841 1 374 31 2 126 653 PLK2,GAPT
SE_02_062500266 chr5:58449497-58462324 Sample_02_0625 Mammary gland WS8_4OHT 266 3 356 29 2 124 653 PLK2,GAPT
SE_02_042900308 chr5:58449559-58462992 Sample_02_0429 Kidney 12364284_VHL+ 308 4 371 31 2 126 653 PLK2,GAPT
SE_02_130800127 chr5:58449883-58463099 Sample_02_1308 Artery Pulmonary artery endothelial cells_caMEK5 127 4 368 31 2 121 653 PLK2,GAPT
SE_02_156900336 chr5:58450044-58462867 Sample_02_1569 Endothelial Endothelial cells 336 1 354 30 2 119 653 PLK2,GAPT
SE_02_076600607 chr5:58450122-58462751 Sample_02_0766 Ovary PEO1 607 3 348 30 2 119 653 PLK2,GAPT
SE_02_039500593 chr5:58450159-58461553 Sample_02_0395 Mammary gland BT-549 593 1 316 28 1 116 653 PLK2,GAPT
SE_02_042800671 chr5:58450345-58462998 Sample_02_0428 Kidney 12364284_VHL- 671 2 351 30 2 119 653 PLK2,GAPT
SE_02_138100260 chr5:58450347-58462767 Sample_02_1381 Pancreas Pancreatic cancer cells_DMSO 260 2 345 30 2 119 653 PLK2,GAPT
SE_02_001100323 chr5:58450360-58462976 Sample_02_0011 Kidney A-498_wtVHL 323 3 351 30 2 119 653 PLK2,GAPT
SE_02_158200360 chr5:58450391-58467047 Sample_02_1582 Renal OS-RC-2 360 5 462 45 2 119 653 PLK2,GAPT
SE_02_001300404 chr5:58450446-58462986 Sample_02_0013 Kidney 786-O_HIF2A 404 5 348 30 2 119 653 PLK2,GAPT
SE_02_125900171 chr5:58450447-58463091 Sample_02_1259 Bone Im-GCT-3504_G34W-repair_WT_4C7 171 3 349 30 2 119 653 PLK2,GAPT
SE_02_001000423 chr5:58450455-58463114 Sample_02_0010 Kidney A-498_emptyvector 423 3 349 30 2 119 653 PLK2,GAPT
SE_02_043000435 chr5:58450488-58463162 Sample_02_0430 Kidney 12364284 435 6 351 30 2 119 653 PLK2,GAPT
SE_02_126000718 chr5:58450554-58462809 Sample_02_1260 Bone Im-GCT-3504_G34W-repair_4F5 718 4 341 30 2 119 653 PLK2,GAPT
SE_02_158100571 chr5:58450557-58467032 Sample_02_1581 Renal OS-LM1 571 5 456 45 2 119 653 PLK2,GAPT
SE_02_093001300 chr5:58450621-58462471 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 1300 14 332 29 2 119 653 PLK2,GAPT
SE_02_049101051 chr5:58450630-58463052 Sample_02_0491 Pharyng Detroit 562-Control 1051 6 345 30 2 119 653 PLK2,GAPT
SE_02_083101127 chr5:58450769-58462491 Sample_02_0831 Umblical vein HUVECs_TNF0min 1127 13 328 29 2 119 653 PLK2,GAPT
SE_02_026800727 chr5:58450993-58463103 Sample_02_0268 Kidney A-498 727 3 335 30 2 119 653 PLK2,GAPT
SE_02_108500259 chr5:58451100-58462771 Sample_02_1085 Retinal Pigmented Epithelial hTERT-RPE1 259 3 325 30 2 118 653 PLK2,GAPT
SE_02_152600235 chr5:58451100-58462782 Sample_02_1526 Lung PC9 DMSO 235 4 325 30 2 118 653 PLK2,GAPT
SE_02_130900198 chr5:58451193-58463037 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 198 2 329 30 2 118 653 PLK2,GAPT
SE_02_123000289 chr5:58451224-58462485 Sample_02_1230 Lung PC9 289 3 317 29 2 118 653 PLK2,GAPT
SE_02_123200170 chr5:58451285-58460857 Sample_02_1232 Lung PC9_siMED13L-2 170 5 264 26 1 114 653 PLK2,GAPT
SE_02_009700188 chr5:58451695-58462208 Sample_02_0097 Foreskin Epidermal-Stem-Cells_shCTRL 188 2 292 26 1 115 653 PLK2,GAPT
SE_02_088400619 chr5:58451910-58463177 Sample_02_0884 Colon LoVo 619 4 312 28 1 118 653 PLK2,GAPT
SE_02_123100224 chr5:58451958-58460889 Sample_02_1231 Lung PC9_siMED13L-1 224 3 250 24 0 114 653 PLK2,GAPT
SE_02_135200579 chr5:58452003-58462308 Sample_02_1352 Mammary gland MDA-MB-231-Erbeta_E2 579 2 291 26 1 116 653 PLK2,GAPT
SE_02_135800647 chr5:58452012-58462668 Sample_02_1358 Other IC8-deltaEGF-L1596H_GSI_2h 647 7 298 27 1 118 653 PLK2,GAPT
SE_02_029500329 chr5:58452050-58463026 Sample_02_0295 Lung A549_TGFBeta_72h 329 1 306 28 1 118 653 PLK2,GAPT
SE_02_135900503 chr5:58452070-58462800 Sample_02_1359 Other IC8-deltaEGF-L1596H_GSI_4h 503 7 302 28 1 118 653 PLK2,GAPT
SE_02_135400570 chr5:58452074-58462238 Sample_02_1354 Mammary gland MDA-MB-231-Erbeta_E2_TNFa 570 1 287 26 1 115 653 PLK2,GAPT
SE_02_138200222 chr5:58452143-58463137 Sample_02_1382 Pancreas Pancreatic cancer cells_Triptolide 222 2 305 28 1 118 653 PLK2,GAPT
SE_02_010800239 chr5:58452166-58461786 Sample_02_0108 Fallopian tube FT246 239 1 271 26 1 115 653 PLK2,GAPT
SE_02_039700527 chr5:58452249-58462845 Sample_02_0397 Mammary gland CAL51-MCF-7 527 2 296 28 1 118 653 PLK2,GAPT
SE_02_112100994 chr5:58452310-58462718 Sample_02_1121 Neonatal foreskin keratinocytes_Mi2KD 994 6 289 28 1 116 653 PLK2,GAPT
SE_02_011600503 chr5:58452346-58463071 Sample_02_0116 Mammary gland MDA-MB-231_untreat 503 1 295 28 1 115 653 PLK2,GAPT
SE_02_005701069 chr5:58452547-58463076 Sample_02_0057 Mammary gland vHMEC 1069 2 294 28 1 115 653 PLK2,GAPT
SE_02_066600162 chr5:58452773-58462273 Sample_02_0666 Prostate RWPE1 Lacz rep1 162 4 265 25 1 112 653 PLK2,GAPT
SE_02_150900528 chr5:58452782-58462870 Sample_02_1509 Lung H3122_LR 528 3 279 27 1 115 653 PLK2,GAPT
SE_02_136800186 chr5:58453040-58462754 Sample_02_1368 Pancreas MIA PaCa-2-untreated 186 2 268 26 1 115 653 PLK2,GAPT
SE_02_136500799 chr5:58453533-58462798 Sample_02_1365 Pancreas AsPC1-untreated 799 3 262 25 1 115 653 PLK2,GAPT
SE_02_065201043 chr5:58453646-58462693 Sample_02_0652 Tracheobronchial epithelial HTBE_H3N2_mock 1043 7 258 25 1 113 653 PLK2,GAPT
SE_02_070500750 chr5:58453749-58467016 Sample_02_0705 Pancreas AsPC1 WT 750 5 371 39 1 113 653 PLK2,GAPT
SE_02_109100264 chr5:58454179-58462637 Sample_02_1091 Mammary gland T47D_shCtrl_shRING1B_8hr 264 3 234 23 1 110 635 PLK2,GAPT
SE_02_064700859 chr5:58455471-58462659 Sample_02_0647 Tracheobronchial epithelial HTBE_H1N1_mock 859 3 208 22 1 88 520 PLK2,GAPT
SE_02_126200513 chr5:58455484-58462840 Sample_02_1262 Bone Im-GCT-3504_G34W 513 2 214 23 1 88 520 PLK2,GAPT
SE_02_126100777 chr5:58455882-58462757 Sample_02_1261 Bone Im-GCT-3504_G34W_unedited 777 3 204 22 1 78 482 PLK2,GAPT
SE_02_064200881 chr5:58456010-58460915 Sample_02_0642 Mammary gland MDA-MB-436_20C paclitaxel 881 2 144 18 0 74 479 PLK2,GAPT
SE_02_061001494 chr5:58456061-58461272 Sample_02_0610 Liposarcoma MLS 1765-92 1494 3 151 19 0 73 475 PLK2,GAPT
SE_02_071201284 chr5:58456668-58462879 Sample_02_0712 Pancreas BxPC3_sgNEG 1284 2 180 22 1 71 432 PLK2,GAPT
SE_02_064500790 chr5:58456695-58463071 Sample_02_0645 Tracheobronchial epithelial HTBE_H1N1_18h 790 2 184 21 1 71 429 PLK2,GAPT
SE_02_132500466 chr5:58456981-58462281 Sample_02_1325 Hindbrain Hindbrain derived neural stem cells_NS19_H3.3K27M_WT 466 3 151 17 1 67 411 PLK2,GAPT
SE_02_064801257 chr5:58456997-58462740 Sample_02_0648 Tracheobronchial epithelial HTBE_H3N2_03h 1257 3 161 19 1 70 410 PLK2,GAPT
SE_02_064300878 chr5:58457020-58460935 Sample_02_0643 Mammary gland MDA-MB-436 878 3 111 15 0 67 407 PLK2,GAPT
SE_02_125400959 chr5:58457110-58460893 Sample_02_1254 Bladder Bladder tumor Basal1 959 2 109 15 0 64 400 PLK2,GAPT
SE_02_065000945 chr5:58457363-58462783 Sample_02_0650 Tracheobronchial epithelial HTBE_H3N2_12h 945 4 154 18 1 60 369 PLK2,GAPT
SE_02_064600673 chr5:58457741-58462874 Sample_02_0646 Tracheobronchial epithelial HTBE_H1N1_24h 673 2 143 15 1 57 344 PLK2,GAPT
SE_02_136600613 chr5:58457766-58462735 Sample_02_1366 Pancreas BxPC3-untreated 613 3 139 15 1 57 342 PLK2,GAPT
SE_02_137100558 chr5:58457898-58462867 Sample_02_1371 Pancreas Patu899S-untreated 558 1 141 15 1 56 339 PLK2,GAPT
SE_02_064900989 chr5:58458062-58462733 Sample_02_0649 Tracheobronchial epithelial HTBE_H3N2_06h 989 2 131 15 1 56 329 PLK2,GAPT
Genomic distribution of SEs associated with PLK2
Genome Browser

The strength of the tissue affected by the gene

Expression of PLK2

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)