SEdb 2.0
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Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000065911
Gene: MTHFD2 Gene type: protein_coding
Strand: + External links:
Genomic region: chr2:74186172-74217565 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_032100464 chr2:74167464-74214562 Sample_02_0321 Peripheral blood MO1043_ICN1_HA_H3K27Ac_b 464 7 1316 113 5 55 778 MTHFD2,MOBKL1B,BOLA3
SE_02_142900388 chr2:74167600-74212805 Sample_02_1429 Blood GM12878_WT 388 11 1267 110 5 48 721 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_02_032000364 chr2:74167712-74214042 Sample_02_0320 Peripheral blood MO1043_ICN1_HA_H3K27Ac_a 364 7 1293 112 5 48 724 MTHFD2,MOBKL1B,BOLA3
SE_02_104603059 chr2:74173555-74207429 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 3059 8 959 92 4 28 431 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_02_057600375 chr2:74175757-74206594 Sample_02_0576 Blood HEL_sgLKB1e2 375 11 863 78 3 28 431 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_02_098700239 chr2:74176430-74207232 Sample_02_0987 Blood K562_Control_1 239 10 859 80 3 28 431 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_02_103200572 chr2:74176575-74207441 Sample_02_1032 Head and neck SCC1 JQ1 572 9 859 80 3 28 431 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_02_103300654 chr2:74176604-74207327 Sample_02_1033 Haematopoietic and lymphoid tissue bone marrow K562 654 5 854 80 3 28 431 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_02_066000580 chr2:74176732-74209826 Sample_02_0660 Mammary gland MCF10DCIS 580 8 914 82 4 33 536 MTHFD2,MOB1A,BOLA3-AS1,BOLA3
SE_01_008501090 chr2:74176739-74208593 Sample_01_0085 Stomach stomach 1090 5 884 79 3 32 500 MTHFD2,MOBKL1B,BOLA3
SE_01_005400468 chr2:74176768-74200801 Sample_01_0054 Haematopoietic and lymphoid tissue OCI-LY3 468 2 668 62 2 16 283 MTHFD2,MOBKL1B,BOLA3
SE_02_040300353 chr2:74176768-74214488 Sample_02_0403 Mammary gland T-47D_untreat 353 4 1035 86 4 49 731 MTHFD2,MOBKL1B,BOLA3
SE_02_010200539 chr2:74176878-74207189 Sample_02_0102 Peripheral blood Macrophages_GM-CSF_72h_IL4 539 4 845 78 3 28 431 MTHFD2,MOBKL1B,BOLA3
SE_02_010100813 chr2:74177175-74207007 Sample_02_0101 Peripheral blood Macrophages_GM-CSF_72h_IFN-y 813 5 831 77 3 28 431 MTHFD2,MOBKL1B,BOLA3
SE_02_034200554 chr2:74177736-74207248 Sample_02_0342 Liver HSPCs_F0 554 5 827 76 3 28 431 MTHFD2,MOBKL1B,BOLA3
SE_01_002100412 chr2:74179918-74207184 Sample_01_0021 Skin bipolar-neuron 412 4 772 66 2 25 271 MTHFD2,BOLA3,MOBKL1B
SE_02_058000446 chr2:74180443-74206953 Sample_02_0580 Blood HEL_sgSIK3e4 446 12 751 65 2 25 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_057900420 chr2:74181028-74206943 Sample_02_0579 Blood HEL_sgNeg2 420 11 739 65 2 25 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_133100747 chr2:74181052-74206714 Sample_02_1331 Blood Molm13_CTRL 747 6 728 63 2 25 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_012400395 chr2:74181060-74210827 Sample_02_0124 Embryo Embryonic-stem-cells_Naive 395 4 836 69 3 36 423 MTHFD2,BOLA3,MOBKL1B
SE_02_057500722 chr2:74181066-74207070 Sample_02_0575 Blood MOLM13_sgLKB1e2 722 7 739 65 2 25 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_057400760 chr2:74181123-74207065 Sample_02_0574 Blood MOLM-13_sgNeg2 760 6 736 65 2 25 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_099400928 chr2:74181135-74207108 Sample_02_0994 Blood MOLM13_SIK3TQ 928 9 737 65 2 25 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_146000409 chr2:74181254-74209469 Sample_02_1460 Blood Mutz-3 409 7 794 67 2 30 373 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_054501049 chr2:74181493-74205874 Sample_02_0545 Bone marrow K562 WT 1049 4 688 59 2 25 247 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_045700505 chr2:74181792-74207860 Sample_02_0457 Th17 lymphocytes Th17-IL-10- Day 5 505 7 733 61 2 29 294 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_139400144 chr2:74182010-74207414 Sample_02_1394 Lymph node anaplastic large cell lymphoma cells_ALK+#208 144 7 721 59 2 23 271 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_045500649 chr2:74184191-74208559 Sample_02_0455 Th17 lymphocytes Th17-IL-10+ Day 5 649 6 680 58 1 26 338 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_103600681 chr2:74186267-74212226 Sample_02_1036 Mammary gland HCC70_XY018 681 12 716 57 2 36 523 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_053200362 chr2:74187636-74213252 Sample_02_0532 Mammary gland T47D 362 11 698 55 2 36 523 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_127300702 chr2:74197350-74211273 Sample_02_1273 Cervix HeLa 702 4 391 30 2 34 449 MTHFD2,BOLA3-AS1,BOLA3,MOB1A
SE_02_040400317 chr2:74197766-74210509 Sample_02_0404 Mammary gland ZR-75-1_2 317 1 353 30 2 32 423 MTHFD2,BOLA3,MOBKL1B
SE_02_055500440 chr2:74197988-74206686 Sample_02_0555 Other HAP1_WT 440 4 250 24 1 22 271 MTHFD2,MOB1A
SE_02_138800685 chr2:74198509-74208095 Sample_02_1388 Peripheral blood JB6_ALK+ 685 2 261 21 1 26 302 MTHFD2,MOB1A
SE_02_122300491 chr2:74198587-74209238 Sample_02_1223 Bone marrow KMS28BM 491 3 285 24 1 25 329 MTHFD2,MOB1A
Genomic distribution of SEs associated with MTHFD2
Genome Browser

The strength of the tissue affected by the gene

Expression of MTHFD2

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)