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Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000161791
Gene: FMNL3 Gene type: protein_coding
Strand: - External links:
Genomic region: chr12:49636499-49708165 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_087500412 chr12:49625867-49707596 Sample_02_0875 Peripheral blood Peripheral blood-derived mast cells 412 30 1960 118 4 280 4709 PRPF40B,FMNL3,TMBIM6,FAM186B,MCRS1
SE_02_044600362 chr12:49627462-49707494 Sample_02_0446 Bone osteosarcoma tumor P2 362 30 1924 114 3 278 4677 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_149200446 chr12:49636206-49707614 Sample_02_1492 Peripheral blood CD34+ derived peripheral blood-derived mast cells 446 20 1716 107 3 270 3604 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_01_008800146 chr12:49636521-49708650 Sample_01_0088 Tibial nerve tibial-nerve 146 9 1731 109 3 272 3604 FMNL3,PRPF40B,FAM186B,TMBIM6
SE_02_155500146 chr12:49636632-49705864 Sample_02_1555 Gastrointestinal Stromal GIST-4_KIT e9 146 16 1659 104 3 253 3348 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_090800201 chr12:49636909-49707484 Sample_02_0908 Heart left ventricle_DCM_LV1262 201 23 1695 107 3 269 3487 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_044400353 chr12:49637297-49707480 Sample_02_0444 Bone osteosarcoma tumor P10 353 23 1683 107 3 269 3466 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_053300216 chr12:49637317-49707485 Sample_02_0533 Blood vessel Circle of Willis_54y 216 18 1682 107 3 269 3464 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_023200232 chr12:49639127-49707319 Sample_02_0232 Tonsil ILC3 232 13 1641 105 3 269 3199 FMNL3,PRPF40B,FAM186B,TMBIM6
SE_02_023400460 chr12:49640257-49707348 Sample_02_0234 Tonsil Th17 460 10 1616 105 3 269 3068 FMNL3,PRPF40B,FAM186B,TMBIM6
SE_02_093000720 chr12:49641617-49707484 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 720 22 1586 103 3 269 2920 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_012700180 chr12:49643975-49708450 Sample_02_0127 Blood Induced-regulatory-T-cells_CPI-703 180 10 1549 104 3 270 2538 FMNL3,PRPF40B,FAM186B,TMBIM6
SE_02_012600209 chr12:49643979-49708614 Sample_02_0126 Blood Induced-regulatory-T-cells_DMSO 209 8 1550 104 3 270 2534 FMNL3,PRPF40B,FAM186B,TMBIM6
SE_02_131500053 chr12:49644449-49707475 Sample_02_1315 Brain hMGLs_INPP5D SNP 53 22 1518 102 3 251 2403 PRPF40B,FMNL3,TMBIM6,FAM186B
SE_02_131600038 chr12:49644725-49707456 Sample_02_1316 Brain hMGLs_TREM2-R47H 38 16 1512 101 3 246 2346 FMNL3,TMBIM6,FAM186B,PRPF40B
SE_02_131300040 chr12:49645134-49716629 Sample_02_1313 Brain hMGLs_CD33_SNP 40 22 1740 124 3 249 2318 FMNL3,TMBIM6,FAM186B,PRPF40B
SE_02_131200129 chr12:49645536-49685519 Sample_02_1312 Brain hMGLs_WT 129 10 975 56 3 200 2030 FMNL3,FAM186B,PRPF40B
SE_02_131700036 chr12:49645566-49707461 Sample_02_1317 Brain hMGLs_SORL1-KO 36 17 1488 100 3 246 2206 FMNL3,TMBIM6,FAM186B,PRPF40B
SE_02_023100162 chr12:49655864-49707144 Sample_02_0231 Tonsil ILC1 162 7 1238 88 3 182 691 FMNL3,TMBIM6,PRPF40B
SE_02_014000400 chr12:49659526-49680960 Sample_02_0140 Kidney RT242 400 6 527 35 3 102 309 FMNL3,PRPF40B
SE_02_141600374 chr12:49659537-49707571 Sample_02_1416 Brain SF9402 374 10 1157 86 3 155 527 FMNL3,TMBIM6,PRPF40B
SE_02_131800202 chr12:49659690-49675608 Sample_02_1318 Brain hMGLs_SORL1-A528T 202 4 399 25 3 89 309 FMNL3,PRPF40B
SE_02_117400313 chr12:49659745-49707475 Sample_02_1174 Brain GBM02 313 18 1151 86 3 155 492 FMNL3,TMBIM6,PRPF40B
SE_02_130300559 chr12:49659870-49707495 Sample_02_1303 Lymphoma RL_tazemetostat 559 24 1151 86 3 155 499 FMNL3,TMBIM6,PRPF40B
SE_02_082601761 chr12:49660029-49674368 Sample_02_0826 Stomach gastric tumor 1761 14 362 22 3 79 309 FMNL3,PRPF40B
SE_02_142900193 chr12:49660151-49707416 Sample_02_1429 Blood GM12878_WT 193 16 1144 85 3 155 481 FMNL3,TMBIM6,PRPF40B,MCRS1,BCDIN3D
SE_02_131400196 chr12:49660168-49676059 Sample_02_1314 Brain hMGLs_TREM2-KO 196 6 404 26 3 89 309 FMNL3,PRPF40B
SE_02_118500386 chr12:49660472-49684515 Sample_02_1185 Brain GBM14 386 7 592 38 3 104 309 FMNL3,PRPF40B
SE_02_155900398 chr12:49660608-49675688 Sample_02_1559 Gastrointestinal Stromal GIST-8_PDGFRA e18 398 4 385 24 3 86 309 FMNL3,PRPF40B
SE_02_058600536 chr12:49660668-49681695 Sample_02_0586 Chordal patient-derived chordoma MGH_4 536 7 532 34 3 99 309 FMNL3,PRPF40B
SE_02_078100699 chr12:49660693-49707452 Sample_02_0781 Lymphoma Pfeiffer_DMSO 699 22 1134 85 3 152 486 FMNL3,TMBIM6,PRPF40B
SE_02_078300861 chr12:49660712-49674520 Sample_02_0783 Blood MEC2 861 5 352 21 3 76 309 FMNL3,PRPF40B
SE_01_005400251 chr12:49660726-49707980 Sample_01_0054 Haematopoietic and lymphoid tissue OCI-LY3 251 5 1147 86 3 155 534 FMNL3,TMBIM6,PRPF40B
SE_02_038700190 chr12:49660772-49699250 Sample_02_0387 Lymph node CD19+_B_cells_nhl_FL1-2 190 15 931 70 3 123 309 FMNL3,TMBIM6,PRPF40B
SE_02_044700154 chr12:49660788-49707488 Sample_02_0447 Lung lung metastasis from primary osteosarcoma tumor M2 154 12 1129 85 3 152 496 FMNL3,TMBIM6,PRPF40B
SE_02_156000440 chr12:49660791-49703908 Sample_02_1560 Gastrointestinal Stromal GIST-9_PDGFRA e18 440 9 1043 78 3 132 309 FMNL3,TMBIM6,PRPF40B
SE_02_078400161 chr12:49660800-49707495 Sample_02_0784 Blood OSU-CLL 161 13 1129 85 3 152 499 FMNL3,TMBIM6,PRPF40B
SE_02_156300095 chr12:49660820-49674744 Sample_02_1563 Gastrointestinal Stromal GIST-12_SDHC deletion 95 8 353 21 3 76 309 FMNL3,PRPF40B
SE_02_032100531 chr12:49660839-49707788 Sample_02_0321 Peripheral blood MO1043_ICN1_HA_H3K27Ac_b 531 4 1137 85 3 155 534 FMNL3,TMBIM6,PRPF40B
SE_02_008100356 chr12:49661242-49707430 Sample_02_0081 Blood Monocyte-derived_dendritic_cells 356 6 1119 83 3 152 482 FMNL3,TMBIM6,PRPF40B
SE_02_118600687 chr12:49661273-49676320 Sample_02_1186 Brain GBM15 687 5 383 26 3 86 309 FMNL3,PRPF40B
SE_02_055700301 chr12:49661377-49675254 Sample_02_0557 iPSCs WT hiPSC#1 301 3 355 23 3 86 309 FMNL3,PRPF40B
SE_02_115200302 chr12:49661592-49707606 Sample_02_1152 Lymphoma RL_WT_gRNA1 302 12 1114 84 3 151 534 FMNL3,TMBIM6,PRPF40B
SE_00_005601156 chr12:49661605-49675326 Sample_00_0056 Sigmoid colon sigmoid colon 3y 1156 7 354 23 3 85 309 FMNL3,PRPF40B
SE_02_119400786 chr12:49661741-49675667 Sample_02_1194 Brain GBM28 786 5 357 23 3 85 309 FMNL3,PRPF40B
SE_02_083900898 chr12:49661780-49675253 Sample_02_0839 Embryo hNPCs_K755R/+ 898 3 348 23 3 85 307 FMNL3,PRPF40B
SE_02_059300364 chr12:49661842-49674623 Sample_02_0593 Fetal spleenocytes fetal naive T cells 364 4 324 20 3 75 293 FMNL3,PRPF40B
SE_02_132000900 chr12:49661863-49675343 Sample_02_1320 Connective Tissue HT1080_EWS-FLI1 900 5 348 23 3 85 289 FMNL3,PRPF40B
SE_02_156500385 chr12:49661892-49674968 Sample_02_1565 Gastrointestinal Stromal Gastrointestinal stromal tumor 385 9 335 22 3 85 285 FMNL3,PRPF40B
SE_02_055600624 chr12:49661918-49674867 Sample_02_0556 iPSCs BOFS hiPSC cl1 624 3 333 21 3 81 283 FMNL3,PRPF40B
SE_02_036600371 chr12:49661956-49676550 Sample_02_0366 Skeletal muscle NCI0082 371 2 379 28 3 85 268 FMNL3,PRPF40B
SE_02_061400585 chr12:49661986-49680611 Sample_02_0614 Liposarcoma MLPS_T2 585 7 463 33 3 90 264 FMNL3,PRPF40B
SE_02_154200339 chr12:49662006-49674820 Sample_02_1542 Gastrointestinal Stromal GIST-T1 339 4 327 21 3 71 261 FMNL3,PRPF40B
SE_00_002500476 chr12:49662043-49676596 Sample_00_0025 Muscle of leg muscle-of-leg 476 2 378 28 3 76 256 FMNL3,PRPF40B
SE_02_087700457 chr12:49662046-49675674 Sample_02_0877 Muscle SMS-CTR_CASZ1b_Dox 457 7 349 23 3 76 254 FMNL3,PRPF40B
SE_02_134300270 chr12:49662107-49674455 Sample_02_1343 Leukophereses leukophereses_p195 270 4 313 20 3 66 241 FMNL3,PRPF40B
SE_02_044500294 chr12:49662116-49707537 Sample_02_0445 Lung lung metastasis from primary osteosarcoma tumor M10 294 19 1097 84 3 142 447 FMNL3,TMBIM6,PRPF40B
SE_02_117500777 chr12:49662152-49674785 Sample_02_1175 Brain GBM03 777 5 321 20 3 69 230 FMNL3,PRPF40B
SE_02_137901093 chr12:49662165-49674855 Sample_02_1379 Pancreas Pancreatic_tumor_associated_fibroblasts_PS1_untreated 1093 4 324 21 3 72 229 FMNL3,PRPF40B
SE_02_155700472 chr12:49662184-49674866 Sample_02_1557 Gastrointestinal Stromal GIST-6_KIT e11/16 472 4 326 21 3 71 227 FMNL3,PRPF40B
SE_00_002600393 chr12:49662222-49675907 Sample_00_0026 Muscle of trunk muscle-of-trunk 393 2 351 24 3 75 211 FMNL3,PRPF40B
SE_02_116000485 chr12:49662233-49699602 Sample_02_1160 Embryo H1_shLuc 485 7 901 69 3 115 211 FMNL3,TMBIM6,PRPF40B
SE_01_011500320 chr12:49662241-49675754 Sample_01_0115 Skeletal Muscle myotube originated from skeletal muscle myoblast 320 3 343 23 3 75 211 FMNL3,PRPF40B,MCRS1,TMBIM6,TUBA1A,FAIM2,FAM186B,BCDIN3D
SE_02_023300691 chr12:49662300-49677492 Sample_02_0233 Tonsil Th1 691 5 381 29 3 76 211 FMNL3,PRPF40B
SE_01_008700349 chr12:49662306-49707930 Sample_01_0087 Thyroid gland thyroid-gland 349 6 1102 85 3 144 436 FMNL3,TMBIM6,PRPF40B
SE_02_137501013 chr12:49662341-49675507 Sample_02_1375 Pancreas Pancreatic_tumor_associated_fibroblasts_B0010A_untreated 1013 6 333 23 3 75 211 FMNL3,PRPF40B
SE_02_155800464 chr12:49662390-49675422 Sample_02_1558 Gastrointestinal Stromal GIST-7_PDGFRA e18 464 5 331 23 3 75 211 FMNL3,PRPF40B
SE_02_061301010 chr12:49662433-49676104 Sample_02_0613 Liposarcoma MLPS_T1 1010 9 345 25 3 75 211 FMNL3,PRPF40B
SE_01_002100341 chr12:49662466-49675848 Sample_01_0021 Skin bipolar-neuron 341 2 336 23 3 75 211 FMNL3,PRPF40B
SE_02_142700962 chr12:49662489-49676309 Sample_02_1427 Shoulder fibroblast_343 962 3 348 25 3 75 211 FMNL3,PRPF40B
SE_02_003600664 chr12:49662522-49705622 Sample_02_0036 Embryo H7 664 8 1030 80 3 125 211 FMNL3,TMBIM6,PRPF40B
SE_02_139300529 chr12:49662527-49684052 Sample_02_1393 Lymph node anaplastic large cell lymphoma cells_ALK+#54 529 5 528 35 3 91 211 FMNL3,PRPF40B
SE_02_104400424 chr12:49662536-49674585 Sample_02_1044 Peripheral blood CD4+ cells_CTCL409 424 10 301 19 3 65 211 FMNL3,PRPF40B
SE_02_021000197 chr12:49662551-49704461 Sample_02_0210 Lung MRC-5_N_1DPT 197 8 1007 78 3 125 211 FMNL3,TMBIM6,PRPF40B
SE_02_021100107 chr12:49662592-49707612 Sample_02_0211 Lung MRC-5_NFD_1DPT 107 10 1084 82 2 142 436 FMNL3,TMBIM6,PRPF40B
SE_02_076201892 chr12:49662614-49707572 Sample_02_0762 Podocyte podocyte_CTL 1892 10 1083 82 2 141 429 FMNL3,TMBIM6,PRPF40B
SE_02_084900655 chr12:49662646-49674801 Sample_02_0849 iPSCs iPSC_CBP-30 655 3 305 18 2 68 211 FMNL3,PRPF40B
SE_02_084800377 chr12:49662687-49674569 Sample_02_0848 iPSCs iPSC_DMSO 377 3 299 18 2 65 211 FMNL3,PRPF40B
SE_02_035000643 chr12:49662700-49675831 Sample_02_0350 Dorsolateral prefrontal cortex dorsolateral-prefrontal-cortex 643 2 331 22 2 75 211 FMNL3,PRPF40B
SE_02_053400264 chr12:49662715-49704599 Sample_02_0534 Blood vessel Circle of Willis_60y 264 19 1006 77 2 125 211 FMNL3,TMBIM6,PRPF40B
SE_02_062100123 chr12:49662777-49674328 Sample_02_0621 Aortic Aortic Endothelial Cells_UF 123 3 285 18 2 65 211 FMNL3,PRPF40B,MCRS1,NCKAP5L,TMBIM6,FAM186B
SE_02_073600443 chr12:49662806-49674917 Sample_02_0736 Blood Pt24_leukemia cell_THZ1 443 8 301 19 2 73 211 FMNL3,PRPF40B
SE_02_044100879 chr12:49662817-49703288 Sample_02_0441 Bone M112 879 16 967 75 2 115 211 FMNL3,TMBIM6,PRPF40B
SE_02_149500208 chr12:49663173-49674269 Sample_02_1495 Other monocyte-derived dendritic cells_R848_1h 208 3 268 17 2 61 211 FMNL3,PRPF40B
SE_02_078500259 chr12:49663380-49674868 Sample_02_0785 Brain 2097 259 5 285 18 2 60 211 FMNL3,PRPF40B
SE_02_080500043 chr12:49663439-49673616 Sample_02_0805 Brain 2223_GBM 43 2 240 14 2 44 211 FMNL3,PRPF40B
SE_02_156100105 chr12:49663488-49674192 Sample_02_1561 Gastrointestinal Stromal GIST-10_PDGFRA e1 105 5 261 16 2 53 211 FMNL3,PRPF40B
SE_00_004300688 chr12:49670349-49676071 Sample_00_0043 Stomach stomach_96d 688 1 148 13 2 32 0 FMNL3,PRPF40B
SE_00_002900296 chr12:49670367-49677456 Sample_00_0029 Ovary ovary 296 3 179 18 2 33 0 FMNL3,PRPF40B
SE_00_003401148 chr12:49670378-49675881 Sample_00_0034 Right cardiac atrium right-cardiac-atrium 1148 1 142 13 2 32 0 FMNL3,PRPF40B
SE_02_043900478 chr12:49672651-49703838 Sample_02_0439 Bone Hu09 478 17 746 60 0 73 0 FMNL3,TMBIM6,PRPF40B
SE_02_010100918 chr12:49688470-49708500 Sample_02_0101 Peripheral blood Macrophages_GM-CSF_72h_IFN-y 918 3 469 40 0 40 225 FMNL3,TMBIM6
SE_02_132100773 chr12:49693790-49707547 Sample_02_1321 Connective Tissue HT1080_FUS-DDIT3 773 3 330 29 0 31 212 FMNL3,TMBIM6
SE_02_132000552 chr12:49693876-49707553 Sample_02_1320 Connective Tissue HT1080_EWS-FLI1 552 3 324 27 0 31 214 FMNL3,TMBIM6
SE_02_076901041 chr12:49694350-49707406 Sample_02_0769 Ovary HEYA8 1041 8 312 24 0 31 170 FMNL3,TMBIM6,MCRS1,PRPF40B,BCDIN3D
SE_02_113800853 chr12:49696869-49707836 Sample_02_1138 Retinal Pigmented Epithelial RPE1-prometaphase 853 4 270 18 0 33 225 FMNL3,TMBIM6
SE_02_093601069 chr12:49697898-49707572 Sample_02_0936 Retinal Pigmented Epithelial RPE188_TnT 1069 2 239 16 0 29 218 FMNL3,TMBIM6
SE_02_113901120 chr12:49698198-49707630 Sample_02_1139 Retinal Pigmented Epithelial RPE1-anaphase/telophase 1120 2 236 16 0 30 225 FMNL3,TMBIM6
SE_02_055700705 chr12:49698302-49707385 Sample_02_0557 iPSCs WT hiPSC#1 705 3 224 15 0 29 164 FMNL3,TMBIM6
SE_02_108000927 chr12:49698465-49707448 Sample_02_1080 Muscle JR1 shCtrl 927 5 225 16 0 29 176 FMNL3,TMBIM6
SE_02_083200451 chr12:49698481-49707525 Sample_02_0832 Umblical vein HUVECs_TNF30min 451 7 224 16 0 29 202 FMNL3,TMBIM6
SE_02_064501873 chr12:49698538-49707571 Sample_02_0645 Tracheobronchial epithelial HTBE_H1N1_18h 1873 3 222 16 0 29 218 FMNL3,TMBIM6
SE_02_132200735 chr12:49698729-49707619 Sample_02_1322 Connective Tissue HT1080_WT 735 2 215 16 0 30 225 FMNL3,TMBIM6
SE_02_064600833 chr12:49699115-49707527 Sample_02_0646 Tracheobronchial epithelial HTBE_H1N1_24h 833 2 200 15 0 29 203 FMNL3,TMBIM6
Genomic distribution of SEs associated with FMNL3
Genome Browser

The strength of the tissue affected by the gene

Expression of FMNL3

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)