About Enhancer
| Enhancer ID: |
|
E_02_139 |
| Enhancer symbol: |
|
-- |
| Species: |
|
Mouse |
| Position : |
|
chr17:35501272-35506872
   |
| Biosample name: |
|
Embryonic Stem Cell |
| Experiment class : |
|
Low throughput |
| Enhancer type: |
|
Super-Enhancer |
| Disease: |
|
-- |
| DO: |
|
-- |
| Mesh: |
|
-- |
| Distance from TSS: |
|
>2KB |
| Pubmed ID: |
|
25801169 |
| Enhancer experiment: |
|
Luciferase Reporter Assay |
| Enhancer experiment description: |
|
The five super-enhancers show physical interactions with their respective associated genes and are located within insulated neighborhoods in the ESC genome , suggesting that these genes represent the bona fide physiological targets of the five SEs. |
About Target gene
| Target gene : |
|
Pou5f1(OCT3,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-4) |
| Strong evidence: |
|
CRISPR/Cas9 |
| Less strong evidence: |
|
-- |
| Target gene experiment description: |
|
Enhancer activity measured in Luciferaseassays in wild type cell and the change in Enhancer activity after OCT4 shutdown is plotted for each constituent Enhancer within the Super-enahncer. |
About TF
| TF name : |
|
-- |
| TF experiment: |
|
-- |
| TF experiment description: |
|
-- |
About Function
| Enhancer function : |
-- |
| Enhancer function experiment: |
-- |
Enhancer function
experiment description: |
-- |
About SNP
| SNP ID: |
|
-- |
| SNP position: |
|
-- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
Expression of target genes for the enhancer
Enhancer associated SNPs
