About Enhancer
| Enhancer ID: | E_02_085 | |
| Enhancer symbol: | -- | |
| Species: | Mouse | |
| Position : | chr1:133347808-133348049   |
|
| Biosample name: | Kidney | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 24734888 |
| Enhancer experiment: | RT-PCR,Southern blot | |
| Enhancer experiment description: | The mdE, defined by 240 bp DNA sequence, was identified by transient transfection of 50 deletion constructs of the mouse Ren-1c gene into As4.1 cells. This tissue-specific enhancer is located 2.6 kb upstream (_x0002_2866 to _x0002_2625 bp) of the transcriptional start site of the mouse renin gene and its homologous sequence is present about 12 kb upstream of the human renin start site of transcription. |
About Target gene
| Target gene : | Ren1(D19352,Ren,Ren-1,Ren-Ac,Ren1d,Rn-1,Rnr,Ren1) | |
| Strong evidence: | -- | |
| Less strong evidence: | Transgenic mice,RT-PCR | |
| Target gene experiment description: | Structural analysis of the transgenic mdE region. In vivo Cre-loxP recombination shown in the left was confirmed by Southern blot analysis of tail DNA from parental,wt,and mut TgM lines,in which the DNA was digested with EcoRI (E),separated on agarosegels,transferred to a nylon membrane,and hybridized to the probe (shaded rectangles in the left panel,from nt 2635 to 2214 relative to transcription start site). The sizes of the expected bands are indicated (in kb) in the right panel and those expected from the endogenous locus are in parentheses. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
