About Enhancer
| Enhancer ID: |
|
E_02_044 |
| Enhancer symbol: |
|
-- |
| Species: |
|
Mouse |
| Position : |
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chr4:115100426-115102426
   |
| Biosample name: |
|
416B |
| Experiment class : |
|
Low throughput |
| Enhancer type: |
|
Enhancer |
| Disease: |
|
-- |
| DO: |
|
-- |
| Mesh: |
|
-- |
| Distance from TSS: |
|
>2KB |
| Pubmed ID: |
|
22396734 |
| Enhancer experiment: |
|
Luciferase Reporter Assay,ChIP,EMSA |
| Enhancer experiment description: |
|
To investigate whether the +45 region functions as a transcriptional enhancer, luciferase reporter constructs were generated using a 1.76 kb genomic fragment encompassing the complete +45 element and their activity was assessed in 416B cells hematopoietic progenitor cells (Figure 1B). |
About Target gene
| Target gene : |
|
Tal1(SCL,TCL5,bHLHa17,tal-1) |
| Strong evidence: |
|
-- |
| Less strong evidence: |
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DNaseI-seq,EMSA,ChIP |
| Target gene experiment description: |
|
Here we report identification of a DNaseI hypersensitive site at the 39 end of the Scl/Map17 domain and 45 kb downstream of the Scl transcription start site.To investigate whether CTCF binding is responsible for the footprinting results observed in Figure 3A, we performed electrophoretic mobility shift assay (EMSA) and ChIP-on-chip experiments. |
About TF
| TF name : |
|
Ctcf(MRD21) |
| TF experiment: |
|
ChIP-seq |
| TF experiment description: |
|
Analysis of publicly available CTCF ChIP-seq data from the ENCODE consortium clearly demonstrates CTCF binding to the +45 element across a wide range of mouse tissues consistent with the presence of a ubiquitous CTCF site. |
About Function
| Enhancer function : |
-- |
| Enhancer function experiment: |
-- |
Enhancer function
experiment description: |
-- |
About SNP
| SNP ID: |
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-- |
| SNP position: |
|
-- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
Expression of target genes for the enhancer
Enhancer associated SNPs
