About Enhancer
| Enhancer ID: | E_02_030 | |
| Enhancer symbol: | -- | |
| Species: | Mouse | |
| Position : | chr15:5249678-5250298   |
|
| Biosample name: | βTC-3 | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 21798992 |
| Enhancer experiment: | Luciferase Reporter Assay | |
| Enhancer experiment description: | The analysisof SLC30A8-luciferase expression in bTC-3 cells revealed that the proximal promoter region, located between K6154 and K1, relativeto the translation startsite, was onlyactivein stablebut not transient transfections.To assess whether chromatin structure was essential for human SLC30A8 and mouse Slc30a8 promoter function, luciferase fusion genes containing either the human SLC30A8 sequence from K6154 to K1 or the mouse Slc30a8 sequence from K1803 to K1 were analyzed in the context of the pGL4 vector. |
About Target gene
| Target gene : | Slc30a8(ZNT8,ZnT-8) | |
| Strong evidence: | -- | |
| Less strong evidence: | PCR,Luciferase Reporter Assay | |
| Target gene experiment description: | To determine whether the C16 579 and C16 954 region of intron 2 in the human SLC30A8 gene also represents a transcriptional enhancer, this region was isolated using PCR and ligated 5 0 of the K150/C3 G6PC2-luciferase fusion gene described above. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
