Enhancer ID: | E_01_366 | |
Enhancer symbol: | -- | |
Species: | Human | |
Position : | chr21:42668000-42671000 |
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Biosample name: | Breast Cancer Cell | |
Experiment class : | Low+High throughput |
Enhancer type: | Enhancer | |
Disease: | -- | |
DO: | -- | |
Mesh: | -- | |
Distance from TSS: | >2KB | |
Pubmed ID: | 26166704 |
Enhancer experiment: | ChIP-seq,ChIP,GRO-seq | |
Enhancer experiment description: | Previous work from our lab and others established that a subgroup of ER-α/H3K27Ac co-bound enhancers (n=1,248,), exhibiting E2-upregulated eRNAs, high intensity of ER-α binding and close proximity to estrogen target genes, constitute the major E2-activated functional enhancers in MCF-7 cells, referred to as E2-induced "active enhancers" or “eRNA+ enhancers”. |
Target gene : | TFF1(BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2) | |
Strong evidence: | 3C | |
Less strong evidence: | ChIP-qPCR | |
Target gene experiment description: | Genome browser image showing the results of GRO-Seq and Pol II ChIP-Seq at TFF1 locus in the presence of condensin knockdown ( siNCAPG or siNCAPD3 ) vs siCTL transfected cell. |
TF name : | -- | |
TF experiment: | -- | |
TF experiment description: | -- |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
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SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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