About Enhancer
| Enhancer ID: | E_01_098 | |
| Enhancer symbol: | -- | |
| Species: | Human | |
| Position : | chr6:31129568-31129735   |
|
| Biosample name: | NT2 | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 22160855 |
| Enhancer experiment: | ChIP,qPCR | |
| Enhancer experiment description: | Chromatin immunoprecipitation analysis of the four regions in the proximal promoter (PP), proximal enhancer (PE1 and PE2),and distal enhancer (DE) unraveled consistent histone marks associated with transcription.Oct4 gene expression is dependent on at least three upstream cis-regulatory regions including proximal pro_x0002_moter (PP) located within the first 250 bp of the tran_x0002_scription initiation site, proximal enhancer (PE) located 1.3-1.6 kb upstream, and distal enhancer (DE) located 2.5 kb upstream. |
About Target gene
| Target gene : | POU5F1(OCT3,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-4) | |
| Strong evidence: | -- | |
| Less strong evidence: | RT-PCR | |
| Target gene experiment description: | To verify induction of differentiation, mRNA level of the stemness marker gene, Oct4, was evaluated in both kinds of cell cultures, using RT-PCR (Fig. 1b) as well as quantitative real-time.As expected,expression of Oct4 gene was dominant in undifferentiated embryonal cells,and rapidly declined following RA-induced differentiation. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
