About Enhancer
| Enhancer ID: |
|
E_01_094 |
| Enhancer symbol: |
|
-- |
| Species: |
|
Human |
| Position : |
|
chr8:117978845-117979466
   |
| Biosample name: |
|
βTC-3,αTC-6 |
| Experiment class : |
|
Low throughput |
| Enhancer type: |
|
Enhancer |
| Disease: |
|
Type 2 Diabetes Mellitus |
| DO: |
|
DOID:9352 |
| Mesh: |
|
D003924 |
| Distance from TSS: |
|
Intron |
| Pubmed ID: |
|
21798992 |
| Enhancer experiment: |
|
Luciferase Reporter Assay,PCR,Transfection |
| Enhancer experiment description: |
|
we have identified a conserved islet beta cell-specific enhancer in SLC30A8 intron
2 (Figs. 4 & 5). |
About Target gene
| Target gene : |
|
SLC30A8(ZNT8,ZnT-8) |
| Strong evidence: |
|
-- |
| Less strong evidence: |
|
Luciferase Reporter Assay,PCR,Transfection |
| Target gene experiment description: |
|
To determine whether the +16579 and +16954 region of intron 2 in the human SLC30A8 gene also represents a transcriptional enhancer, this region was isolated using PCR and ligated 5' of the −150/+3 G6PC2-luciferase fusion gene described above. Luciferase expression directed by this fusion gene was then analyzed by transient transfection of βTC-3 and αTC-6 cells. |
About TF
| TF name : |
|
-- |
| TF experiment: |
|
-- |
| TF experiment description: |
|
-- |
About Function
| Enhancer function : |
-- |
| Enhancer function experiment: |
-- |
Enhancer function
experiment description: |
-- |
About SNP
| SNP experiment: |
|
Luciferase Reporter Assay,PCR |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
Expression of target genes for the enhancer
Enhancer associated SNPs
