About Enhancer
| Enhancer ID: | E_01_038 | |
| Enhancer symbol: | FKBP51 Enhancer | |
| Species: | Human | |
| Position : | chr6:35574362-35576362   |
|
| Biosample name: | A549 | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 20093418 |
| Enhancer experiment: | RT-qPCR,ChIP | |
| Enhancer experiment description: | According to our quantitative ChIP and enhancer assays, there are at least three major distal gene regions that significantly bind GR and also function as strong GR-regulated enhancers in isolation. |
About Target gene
| Target gene : | FKBP4(FKBP51,FKBP52,FKBP59,HBI,Hsp56,PPIase,p52) | |
| Strong evidence: | -- | |
| Less strong evidence: | ChIP,Luciferase Reporter Assay | |
| Target gene experiment description: | Our quantitative chromatin immunoprecipitation scans and enhancer activity analyses indicate that activation of the FKBP51 locus by glucocorticoids in vivo is triggered by the loading of GR to enhancers at about 34 kb 5 and about 87 kb 3 of the transcription start site. |
About TF
| TF name : | CTCF(MRD21) | |
| TF experiment: | ChIP | |
| TF experiment description: | We used the genome-wide CTCF-binding information from the CTCF-binding site database for choosing the regions to be ChIP scanned with anti-CTCF antibody. |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
