Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03382
Species: Mus musculus
Position : chr5:137489416-137503216
Year: 2017
Title: Renal Anemia Model Mouse Established by Transgenic Rescue with an Erythropoietin Gene Lacking Kidney-Specific Regulatory Elements.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: anemia
PMID:  27920250
MONDO: MONDO:0002280
Tissue: kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: Renal EPO-producing (REP) cells
Cell Type: fibroblast-like renal EPO-producing cell
Experiment Type: Enhancer activity assay; Functional perturbation assay; In vivo transgenic rescue assay; Gene expression assay
Low Throughput Method: BAC transgenic reporter assay; CURE deletion in BAC transgene; transgenic complementation rescue; GFP immunohistochemistry; qRT-PCR; plasma EPO ELISA
About Target Gene
Target gene : Epo
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer