About Enhancer
| Enhancer ID: | E_03322 |
| Species: | Mus musculus |
| Position : | chr11:32165011-32165922   |
| Year: | 2012 |
| Title: | Intragenic enhancers act as alternative promoters. |
| Genome Build: | mm9 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 22264824 |
| Tissue: | liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | primary Ter119+ erythroid cells |
| Cell Type: | erythroid cell |
| Experiment Type: | Enhancer chromatin-state assay; Enhancer-derived transcription assay; Alternative-promoter assay |
| High Throughput Method: | H3K4me1 ChIP-seq; H3K4me3 ChIP-seq; H3K27ac ChIP-seq; H3K27me3 ChIP-seq; RNAP2 ChIP-seq; DNase-seq; RNA-seq; published erythroid TF ChIP-seq integration |
| Low Throughput Method: | RT-qPCR; Northern blot |
About Target Gene
| Target gene : | Hba-a1 |
About TF
| TF name : | Gata1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Gata1 | C-MYB transcription factor network | pid | 87 |
| Gata1 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| Gata1 | IL3 | netpath | 84 |
| Gata1 | Notch-mediated HES/HEY network | pid | 48 |
| Gata1 | p73 transcription factor network | pid | 80 |
| Gata1 | Signaling events mediated by HDAC Class I | pid | 89 |
| Gata1 | Signaling events mediated by HDAC Class II | pid | 58 |
Enhancer Associated Network
Overlapping Enhancers (mm9)
16 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02494 | chr11:32145540-32169344 | NA | primitive erythroid lineage cell | NA |
| E_02495 | chr11:32145540-32169344 | NA | primitive erythroid lineage cell | NA |
| E_00112 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00113 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00114 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00115 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00116 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00117 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00118 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_00119 | chr11:32165011-32165922 | liver | erythroblast | NA |
| E_03490 | chr11:32165011-32165922 | spleen | erythroblast | NA |
| E_03491 | chr11:32165011-32165922 | spleen | erythroblast | NA |
| E_03492 | chr11:32165011-32165922 | spleen | erythroblast | NA |
| E_03493 | chr11:32165011-32165922 | spleen | erythroblast | NA |
| E_03494 | chr11:32165011-32165922 | spleen | erythroblast | NA |
| E_03495 | chr11:32165011-32165922 | spleen | erythroblast | NA |
Expression of Target Genes for the Enhancer