Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03299
Species: Mus musculus
Position : chr11:98979280-98979880
Year: 2015
Title: MyoR modulates cardiac conduction by repressing Gata4.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  25487574
Tissue: heart
Tissue Ontology ID: UBERON:0000948
Cell Source: COS-7
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; In vivo functional validation
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RT-qPCR/qPCR; Western blot
About Target Gene
Target gene : Gjd3
About TF
TF name : Tbx5
About Regulatory State
Regulatory State : Repressed
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Tbx5 Physiological factors reactome 12
Tbx5 YAP1- and WWTR1 (TAZ)-stimulated gene expression reactome 29
Tbx5 Hs_Heart_Development_WP1591_90186 wikipathways 28
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_03297 chr11:98979280-98979880 heart NA NA
E_03298 chr11:98979280-98979880 heart NA NA
Expression of Target Genes for the Enhancer